Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   GO602_RS24375 Genome accession   NZ_CP046602
Coordinates   5216471..5217808 (+) Length   445 a.a.
NCBI ID   WP_024914651.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain CMC-115     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 5211471..5222808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO602_RS24350 (GO602_24325) pgeF 5211614..5212342 (-) 729 WP_024914656.1 peptidoglycan editing factor PgeF -
  GO602_RS24355 (GO602_24330) rluD 5212339..5213301 (-) 963 WP_024914655.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  GO602_RS24360 (GO602_24335) - 5213447..5214472 (+) 1026 WP_024914654.1 outer membrane protein assembly factor BamD -
  GO602_RS24365 (GO602_24340) - 5214629..5214874 (+) 246 WP_024914653.1 PP0621 family protein -
  GO602_RS24370 (GO602_24345) pilS 5214864..5216456 (+) 1593 WP_024914652.1 two-component system sensor histidine kinase PilS Regulator
  GO602_RS24375 (GO602_24350) pilR 5216471..5217808 (+) 1338 WP_024914651.1 two-component system response regulator PilR Regulator
  GO602_RS24380 (GO602_24355) thiO 5217853..5218947 (-) 1095 WP_024914650.1 glycine oxidase ThiO -
  GO602_RS24385 (GO602_24360) - 5219082..5219591 (+) 510 WP_024914649.1 Tfp pilus assembly protein FimT/FimU -
  GO602_RS24390 (GO602_24365) - 5219697..5220203 (+) 507 WP_003102598.1 Tfp pilus assembly protein FimT/FimU -
  GO602_RS24395 (GO602_24370) pilV 5220194..5220751 (+) 558 WP_058141282.1 type 4a pilus minor pilin PilV Machinery gene
  GO602_RS24400 (GO602_24375) pilW 5220748..5221572 (+) 825 WP_058141283.1 type 4a pilus minor pilin PilW -
  GO602_RS24405 (GO602_24380) pilX 5221569..5222156 (+) 588 WP_003112826.1 type 4a pilus minor pilin PilX -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49768.07 Da        Isoelectric Point: 5.6424

>NTDB_id=405975 GO602_RS24375 WP_024914651.1 5216471..5217808(+) (pilR) [Pseudomonas aeruginosa strain CMC-115]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTDDAQEKLKSYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=405975 GO602_RS24375 WP_024914651.1 5216471..5217808(+) (pilR) [Pseudomonas aeruginosa strain CMC-115]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAGCTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGCTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCATACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTACGGGAGCTGGTGGCGACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCCCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAACTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGCGGCGAGTCCGGCAGCGGCAAGGAGCTGGTAGCGCGCCTGATCCACGAACAGGGGCCACGCATAGAGCGGCCTTT
CGTCCCGGTGAACTGCGGCGCGATTCCCTCCGAGCTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTCTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAGCTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTACGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGTGTGCCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGACGACGCACAGGAAAAACTGAAGAGCTACCG
TTTCCCCGGCAACGTCCGCGAGCTGGAGAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTTGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCGGCGAGCCTGAGCGAGATCGACAACCTCGAGGAT
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACCTTCCGCTCTATGCGCTACCGCCTGAAAAAGCTCGGCATCGACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(7-115)

Sigma-54 interaction domain (Sigma54_activat)

(135-301)

Bacterial regulatory protein, Fis family (HTH_8)

(402-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

99.551

100

0.996
  pilR Acinetobacter baumannii strain A118

51.198

100

0.528
  luxO Vibrio cholerae strain A1552

38.17

100

0.384

Multiple sequence alignment