Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   GOM46_RS06445 Genome accession   NZ_CP046525
Coordinates   1291884..1292546 (+) Length   220 a.a.
NCBI ID   WP_006149819.1    Uniprot ID   F5VY78
Organism   Streptococcus infantis strain SO     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1286884..1297546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS06400 (GOM46_06385) - 1287488..1287739 (-) 252 WP_006149852.1 hypothetical protein -
  GOM46_RS06405 (GOM46_06390) - 1287907..1288152 (-) 246 WP_235083352.1 DUF4190 domain-containing protein -
  GOM46_RS06410 (GOM46_06395) - 1288334..1288561 (-) 228 WP_006149827.1 hypothetical protein -
  GOM46_RS06415 (GOM46_06400) - 1288652..1289032 (-) 381 WP_006149793.1 rhodanese-like domain-containing protein -
  GOM46_RS06420 (GOM46_06405) - 1289038..1289262 (-) 225 WP_000646475.1 YqgQ family protein -
  GOM46_RS06425 (GOM46_06410) - 1289321..1289782 (-) 462 WP_235083353.1 ECF transporter S component -
  GOM46_RS06430 (GOM46_06415) - 1289760..1290533 (-) 774 WP_006149815.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  GOM46_RS06435 (GOM46_06420) truA 1290523..1291272 (-) 750 WP_006149953.1 tRNA pseudouridine(38-40) synthase TruA -
  GOM46_RS06440 (GOM46_06425) - 1291358..1291813 (-) 456 WP_235083354.1 GNAT family N-acetyltransferase -
  GOM46_RS06445 (GOM46_06430) cclA/cilC 1291884..1292546 (+) 663 WP_006149819.1 prepilin peptidase Machinery gene
  GOM46_RS06450 (GOM46_06435) trpA 1292515..1293297 (-) 783 WP_006149858.1 tryptophan synthase subunit alpha -
  GOM46_RS06455 (GOM46_06440) trpB 1293290..1294513 (-) 1224 WP_006149843.1 tryptophan synthase subunit beta -
  GOM46_RS06460 (GOM46_06445) - 1294491..1295090 (-) 600 WP_006149903.1 phosphoribosylanthranilate isomerase -
  GOM46_RS06465 (GOM46_06450) trpC 1295077..1295844 (-) 768 WP_006149820.1 indole-3-glycerol phosphate synthase TrpC -
  GOM46_RS06470 (GOM46_06455) trpD 1295841..1296845 (-) 1005 WP_006149842.1 anthranilate phosphoribosyltransferase -
  GOM46_RS06475 (GOM46_06460) - 1296856..1297422 (-) 567 WP_006149948.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25086.56 Da        Isoelectric Point: 8.3866

>NTDB_id=405082 GOM46_RS06445 WP_006149819.1 1291884..1292546(+) (cclA/cilC) [Streptococcus infantis strain SO]
MIHLYFFLVGTILASFLGLVIDRFPEQSIVFPASHCDSCQTPLRPLDLIPIVSQVIGRFRCRYCKVRYPFWYAFFELGSG
LLFLAFSWKILTLSQVILITAGLTLGIYDFRHQEYPLIVWLIFHLILMVCSSWNLIMVFFLVLGIIAHVIDIRIGAGDFL
FLTSCALIFSLTEMLILIQFASTIGILAFLLLRKKERLPFVPFLLLAACVIIFGKLLLLG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=405082 GOM46_RS06445 WP_006149819.1 1291884..1292546(+) (cclA/cilC) [Streptococcus infantis strain SO]
ATGATTCATCTTTACTTTTTTCTTGTTGGAACGATTCTTGCTTCCTTTCTAGGCTTGGTCATTGATCGCTTTCCTGAACA
ATCCATCGTATTTCCTGCAAGTCACTGTGATTCTTGTCAGACTCCTTTGAGACCTCTGGATTTGATTCCAATTGTTTCTC
AAGTAATTGGGCGCTTTCGCTGTCGCTATTGTAAGGTACGATATCCTTTCTGGTATGCTTTCTTTGAGTTAGGCTCGGGA
CTGCTCTTTCTAGCTTTTTCTTGGAAAATTCTAACCTTGAGTCAAGTCATCCTAATCACTGCCGGTTTAACTTTGGGAAT
CTATGACTTTCGACATCAAGAATACCCCTTAATCGTCTGGCTAATATTTCACTTAATTCTCATGGTTTGCTCTAGTTGGA
ATCTAATCATGGTTTTCTTCCTAGTTCTTGGAATCATTGCCCATGTTATCGATATCCGTATAGGAGCAGGTGATTTTCTC
TTTCTAACTTCTTGTGCCCTTATTTTTAGCCTAACTGAAATGCTGATTCTCATTCAATTTGCTTCTACAATCGGCATTCT
AGCCTTTCTCCTGCTAAGGAAAAAGGAAAGACTTCCTTTTGTGCCTTTCCTATTACTTGCTGCTTGCGTGATTATTTTTG
GTAAGCTACTGCTTCTTGGATAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F5VY78

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis NCTC 12261

81.735

99.545

0.814
  cclA/cilC Streptococcus pneumoniae Rx1

81.279

99.545

0.809
  cclA/cilC Streptococcus pneumoniae D39

81.279

99.545

0.809
  cclA/cilC Streptococcus pneumoniae R6

81.279

99.545

0.809
  cclA/cilC Streptococcus mitis SK321

80.365

99.545

0.8
  cclA/cilC Streptococcus pneumoniae TIGR4

78.995

99.545

0.786

Multiple sequence alignment