Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GOM46_RS02575 Genome accession   NZ_CP046525
Coordinates   507387..508124 (+) Length   245 a.a.
NCBI ID   WP_006150176.1    Uniprot ID   F5VZI6
Organism   Streptococcus infantis strain SO     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 502387..513124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS02555 (GOM46_02540) - 502941..503978 (+) 1038 WP_235083917.1 prephenate dehydratase -
  GOM46_RS02560 (GOM46_02545) - 504132..505619 (+) 1488 WP_235083918.1 oligosaccharide flippase family protein -
  GOM46_RS02565 (GOM46_02550) - 505629..506432 (+) 804 WP_235083919.1 LicD family protein -
  GOM46_RS02570 (GOM46_02555) - 506433..507239 (+) 807 WP_195183746.1 LicD family protein -
  GOM46_RS02575 (GOM46_02560) mecA 507387..508124 (+) 738 WP_006150176.1 adaptor protein MecA Regulator
  GOM46_RS02580 (GOM46_02565) - 508271..508834 (+) 564 WP_235083920.1 TIGR01440 family protein -
  GOM46_RS02585 (GOM46_02570) - 508999..509559 (+) 561 WP_235083921.1 redoxin family protein -
  GOM46_RS02590 (GOM46_02575) msrB 509569..510684 (+) 1116 WP_235083922.1 peptide-methionine (R)-S-oxide reductase MsrB -
  GOM46_RS02595 (GOM46_02580) pabB 510758..512479 (+) 1722 WP_235083923.1 aminodeoxychorismate synthase component I -
  GOM46_RS02600 (GOM46_02585) - 512480..513097 (+) 618 WP_235083924.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28499.27 Da        Isoelectric Point: 3.9680

>NTDB_id=405060 GOM46_RS02575 WP_006150176.1 507387..508124(+) (mecA) [Streptococcus infantis strain SO]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMDELAKMSPDEFLKTLEKTMAEKTKEDIEAIQSLEQVEKEEEAAIEEISELEEGKREPYIYYILRF
DDLTSLVSFAKTVDYQMETSELYKMNDQYYLTVLVDVEDHPSLYPAWLLARMREFADDSDISRSVLQEYGQVIINHDAVQ
GLQKV

Nucleotide


Download         Length: 738 bp        

>NTDB_id=405060 GOM46_RS02575 WP_006150176.1 507387..508124(+) (mecA) [Streptococcus infantis strain SO]
ATGAAAATGAAACAAATCAGTGATACAACTTTAAAAATCACGATGTCTCTAGAAGATTTGATGGATCGTGGAATGGAAAT
CGCTGACTTTCTCGTTCCACAAGAAAAAACAGAAGAGTTTTTCTATGCAATCTTGGATGAGCTAGAAATGCCAGACAGCT
TTTTGGATACAGGTATGCTTAGCTTCCGAGTAACACCGAAACCTGATAAGGTTGATGTCTTTGTGACGAAATCTAAGATT
GATCAGAACTTGGATTTTGAAGATTTGGCAGATCTTCCAGATATGGATGAGTTGGCGAAAATGTCTCCAGATGAGTTTCT
GAAAACATTGGAAAAAACCATGGCAGAAAAAACAAAAGAAGATATTGAAGCTATTCAATCTTTAGAACAGGTTGAAAAAG
AAGAGGAAGCAGCGATTGAGGAAATTTCTGAACTTGAAGAAGGAAAAAGAGAACCTTATATCTACTACATCTTACGATTT
GACGACTTAACTAGTTTGGTTTCTTTTGCAAAGACAGTCGATTACCAAATGGAGACTTCAGAACTTTACAAGATGAATGA
CCAATATTATCTAACAGTTTTGGTAGATGTAGAGGATCATCCAAGTCTTTATCCAGCTTGGTTATTGGCACGCATGCGCG
AATTTGCGGATGATAGTGATATTAGTCGCTCAGTACTTCAAGAATATGGACAAGTCATCATCAATCATGATGCTGTTCAA
GGACTTCAAAAAGTATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F5VZI6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

82.449

100

0.824
  mecA Streptococcus pneumoniae D39

82.449

100

0.824
  mecA Streptococcus pneumoniae R6

82.449

100

0.824
  mecA Streptococcus pneumoniae TIGR4

82.449

100

0.824
  mecA Streptococcus mutans UA159

52.033

100

0.522
  mecA Streptococcus thermophilus LMD-9

46.988

100

0.478
  mecA Streptococcus thermophilus LMG 18311

46.586

100

0.473

Multiple sequence alignment