Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GOM47_RS03580 Genome accession   NZ_CP046524
Coordinates   690880..691620 (+) Length   246 a.a.
NCBI ID   WP_235081113.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOT     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 685880..696620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM47_RS03570 (GOM47_03560) - 686707..689232 (+) 2526 WP_235081111.1 MBL fold metallo-hydrolase -
  GOM47_RS03575 (GOM47_03565) - 689280..690758 (-) 1479 WP_235081112.1 oligosaccharide flippase family protein -
  GOM47_RS03580 (GOM47_03570) mecA 690880..691620 (+) 741 WP_235081113.1 adaptor protein MecA Regulator
  GOM47_RS03585 (GOM47_03575) - 691741..693027 (+) 1287 WP_235081114.1 homoserine dehydrogenase -
  GOM47_RS03590 (GOM47_03580) thrB 693029..693898 (+) 870 WP_235081115.1 homoserine kinase -
  GOM47_RS03595 (GOM47_03585) msrB 694150..695088 (+) 939 WP_235081116.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28551.34 Da        Isoelectric Point: 4.0759

>NTDB_id=404986 GOM47_RS03580 WP_235081113.1 690880..691620(+) (mecA) [Streptococcus oralis strain SOT]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFDDLADLPDMEELAQMSPDEFLKTLEKSIAEKTKDDIEAIQSLEQVEAKEEELEQANKETESKKEPYIYYILRFA
NLADLVAFAKTVNYQMETSELYKMNDHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKINN

Nucleotide


Download         Length: 741 bp        

>NTDB_id=404986 GOM47_RS03580 WP_235081113.1 690880..691620(+) (mecA) [Streptococcus oralis strain SOT]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAAAT
CGCAGACTTTCTCGTTCCTCAGGAAAAAACAGAAGAGTTTTTCTATGCTATTTTAGATGAACTGGAAATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGTGTGACGCCAAAACCTGATAAGGTGGATGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATCTAGATTTTGATGATTTGGCGGACCTACCTGACATGGAAGAATTGGCCCAAATGTCACCAGATGAATTTCT
CAAGACACTAGAAAAGAGTATCGCAGAGAAAACCAAGGATGATATAGAGGCTATTCAATCCCTAGAACAGGTCGAGGCTA
AGGAAGAGGAGCTGGAGCAAGCGAACAAGGAGACTGAGAGCAAGAAGGAACCTTATATCTACTATATCTTGCGTTTCGCA
AATCTTGCTGACCTAGTTGCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGACCA
CTATTATTTGACAATCTTAGTTGATGTGGAAAACCATCCTAGTCCATATCCAGCCTGGCTCTTGGCTCGTATGCGTGAAT
TTGCTGACGACAGTGATATCAGTCGTTCAGTCTTGCAGGAATATGGTCAAATTTTGATCAATCATGATGCCGTGCTTGGT
CTTCAAAAAATCAACAATTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

89.388

99.593

0.89
  mecA Streptococcus pneumoniae D39

89.388

99.593

0.89
  mecA Streptococcus pneumoniae R6

89.388

99.593

0.89
  mecA Streptococcus pneumoniae TIGR4

88.98

99.593

0.886
  mecA Streptococcus mutans UA159

48.98

99.593

0.488
  mecA Streptococcus thermophilus LMD-9

47.791

100

0.484
  mecA Streptococcus thermophilus LMG 18311

47.39

100

0.48

Multiple sequence alignment