Detailed information NTG0404925

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GOM48_RS06215
• Genome accession: NZ_CP046523
• Coordinates: 1223782..1226022 (-)
• Length: 746 a.a.
• NCBI ID: WP_235096462.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOD
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1218782..1231022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM48_RS06180 (GOM48_06175)	-	1219684..1220064 (-)	381	WP_235096459.1	VOC family protein	-
GOM48_RS06185 (GOM48_06180)	rplT	1220123..1220482 (-)	360	WP_000124830.1	50S ribosomal protein L20	-
GOM48_RS06190 (GOM48_06185)	rpmI	1220534..1220734 (-)	201	WP_001125942.1	50S ribosomal protein L35	-
GOM48_RS06195 (GOM48_06190)	infC	1220767..1221297 (-)	531	WP_000848184.1	translation initiation factor IF-3	-
GOM48_RS06200 (GOM48_06195)	-	1221600..1222784 (-)	1185	WP_235096460.1	hypothetical protein	-
GOM48_RS06205 (GOM48_06200)	-	1222781..1223374 (-)	594	WP_235096461.1	ATP-binding cassette domain-containing protein	-
GOM48_RS06210	-	1223407..1223595 (-)	189	WP_235098753.1	hypothetical protein	-
GOM48_RS06215 (GOM48_06205)	comEC/celB	1223782..1226022 (-)	2241	WP_235096462.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GOM48_RS06220 (GOM48_06210)	comEA/celA/cilE	1226006..1226656 (-)	651	WP_235096463.1	helix-hairpin-helix domain-containing protein	Machinery gene
GOM48_RS06225 (GOM48_06215)	-	1226723..1227292 (-)	570	WP_235096464.1	GNAT family N-acetyltransferase	-
GOM48_RS06230 (GOM48_06220)	ald	1227469..1228581 (+)	1113	WP_235096465.1	alanine dehydrogenase	-
GOM48_RS06235 (GOM48_06225)	-	1228644..1229630 (-)	987	WP_235096466.1	PhoH family protein	-
GOM48_RS06240 (GOM48_06230)	-	1229711..1229926 (-)	216	WP_001232084.1	YozE family protein	-
GOM48_RS06245 (GOM48_06235)	-	1229923..1230528 (-)	606	WP_235096467.1	GrpB family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84345.39 Da
• Isoelectric Point: 9.0389

>NTDB_id=404925 GOM48_RS06215 WP_235096462.1 1223782..1226022(-) (comEC/celB) [Streptococcus oralis strain SOD]
MSQWTKNFPIPLIYLSFLLLWLYYAIFGASYLALLGFVFLLVCLFLQFPWKSAGKVLAICGVFGFWFLFQTWQQTQASQD
LVGYVEKVRILPDTIKVNGDSLSFRGKADGRTFQVYYKLQSEEEKEQFQALTALHDLELEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQTLTIKSIQSLKKVSSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDAFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGLKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDVVFLPLLSI
LFILSFVYPVTQFNIVFEWLENIIRLVSQLASRPLVFGQPNAWLLILLLVSLALVYDMRKNIKRLAGFSLFIVGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIEKWQEKATTSNAQRTVIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTNAFHVGEILVSKGSLTQKEFVAELEASQTKVRSVTAGENLPIFGSQLEVLSPRQIGDGSHSDSLLLYGKL
LDKHFLFSGNLKEKGEKDLLKQYPDLEVDVLKVGQHGSKTSSNPAFLEKLNPEISLISVGKNNRAKLPHQETLTRLETIK
SKIYRTDQNGAIRFKGWNSWQIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=404925 GOM48_RS06215 WP_235096462.1 1223782..1226022(-) (comEC/celB) [Streptococcus oralis strain SOD]
ATGTCACAGTGGACTAAAAACTTCCCTATTCCTCTAATCTATCTGAGCTTTCTGTTGCTCTGGCTTTACTATGCCATTTT
TGGAGCGTCCTATCTCGCACTGCTAGGTTTTGTTTTTTTACTTGTCTGTCTCTTTTTACAATTTCCTTGGAAATCTGCTG
GAAAAGTTCTAGCGATTTGTGGAGTTTTTGGATTTTGGTTTCTGTTTCAAACTTGGCAACAGACACAAGCGAGTCAAGAC
TTGGTTGGCTATGTTGAAAAGGTGAGGATTTTACCAGATACCATCAAAGTCAATGGAGATAGTCTGTCCTTTCGTGGCAA
GGCTGACGGCCGTACATTCCAAGTTTACTATAAACTTCAGTCCGAAGAAGAGAAAGAGCAATTTCAAGCCTTAACAGCCC
TTCATGACTTGGAACTAGAAGGGAAGCTTTCAGAGCCAGAAGGTCAGAGGAATTTTGGTGGATTTGACTACCAAGCCTAT
CTGAAAACTCAAGGGATTTACCAGACACTGACTATCAAGAGCATCCAGTCACTTAAAAAGGTTAGCAGTTGGGATATAGG
TGAAAATTTATCAAGTTTACGTCGAAAGGCTGTAGTTTGGATCAAGACGCACTTTCCAGACCCTATGCGCAACTATATGA
CAGGTCTTCTGTTAGGACATCTGGATACGGACTTTGAGGAGATGAATGAACTTTATTCTAGTCTAGGAATTATCCATCTC
TTTGCCTTGTCGGGTATGCAGGTGGGCTTCTTTATGGATGCCTTTAAGAAACTTCTCTTACGATTGGGCTTGACCCAAGA
AAAGTTGAAGTGGCTGACCTATCCTTTTTCCCTTATCTATGCAGGTCTGACAGGATTTTCAGCTTCGGTCATTCGCAGTC
TCTTGCAAAAGTTACTGGCCCAACATGGTCTTAAGGGTTTGGATAATTTTGCCTTGACGGTCCTTGTCCTCTTTATCATC
ATGCCTAACTTTTTCTTGACAGCTGGAGGGGTCTTGTCCTGCGCCTACGCTTTTATCTTGACCATGACTAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCAAGAGAAAGTCTGGTCATTTCCTTGGGAATATTGCCTATTCTATCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTGTTTGATGTGGTCTTCTTGCCGCTTTTGTCCATC
TTATTCATTCTGTCTTTTGTTTACCCAGTCACTCAGTTTAACATTGTCTTTGAGTGGTTGGAGAACATCATTCGCTTGGT
ATCGCAGCTGGCAAGCAGGCCTCTGGTCTTTGGTCAACCCAATGCATGGCTTTTGATTCTTCTCTTAGTTTCATTAGCCT
TGGTATATGACATGAGAAAAAACATCAAAAGACTAGCAGGATTCAGTCTCTTTATTGTGGGTCTCTTTTTCTTGACCAAG
TATCCACTGGAAAATGAAATTACCATGCTGGATGTAGGGCAAGGGGAAAGTATTTTCCTACGGGATGTAACAGGTAAAAC
CATTCTCATAGATGTGGGAGGCAAGGCAGAATCTGATAAGAAAATCGAAAAATGGCAAGAAAAGGCGACGACCAGCAATG
CCCAGCGAACCGTGATTCCTTATCTTAAAAGTCGTGGGGTAGCCAAGATTGATCAGTTGATTTTGACCAACACAGACAAG
GAACATGTTGGTGATTTGCTAGAGGTGACCAATGCTTTCCATGTCGGGGAAATTTTAGTATCAAAAGGAAGTCTGACACA
GAAGGAATTTGTAGCAGAACTAGAAGCAAGCCAAACCAAGGTGCGCAGTGTGACAGCAGGGGAGAACTTGCCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGCAGATTGGAGATGGAAGTCATAGTGATTCCCTCCTTCTTTATGGGAAACTC
TTGGATAAGCACTTTCTCTTCAGTGGAAACTTGAAAGAGAAGGGAGAGAAGGATCTTTTAAAGCAATATCCTGACTTAGA
GGTGGATGTCTTGAAAGTCGGTCAACATGGTTCTAAAACCTCATCAAATCCAGCTTTTCTAGAAAAACTCAACCCAGAGA
TTTCTCTCATATCAGTTGGAAAGAACAATCGTGCGAAACTCCCCCATCAGGAAACCTTGACTCGACTAGAGACCATCAAG
AGTAAGATTTACCGCACTGACCAGAACGGAGCTATTCGCTTTAAAGGATGGAATAGTTGGCAAATCGAAAGTGTTCGTTA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-700)

• Domain of unknown function (DUF4131) (DUF4131) (31-177)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	89.812	100	0.898
comEC/celB	Streptococcus mitis NCTC 12261	88.054	99.866	0.879
comEC/celB	Streptococcus pneumoniae TIGR4	86.863	100	0.869
comEC/celB	Streptococcus pneumoniae Rx1	86.193	100	0.862
comEC/celB	Streptococcus pneumoniae D39	86.193	100	0.862
comEC/celB	Streptococcus pneumoniae R6	86.193	100	0.862
comEC	Lactococcus lactis subsp. cremoris KW2	45.479	99.33	0.452