Detailed information NTG0404916

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: GOM48_RS04145
• Genome accession: NZ_CP046523
• Coordinates: 821802..822650 (+)
• Length: 282 a.a.
• NCBI ID: WP_235098528.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SOD
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 816802..827650

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GOM48_RS04125 (GOM48_04105)	-	816898..817329 (+)	432	WP_125415990.1	arginine repressor	-
GOM48_RS04130 (GOM48_04110)	recN	817336..819003 (+)	1668	WP_235098524.1	DNA repair protein RecN	-
GOM48_RS04135 (GOM48_04115)	-	819005..819733 (+)	729	WP_235098526.1	metallophosphoesterase family protein	-
GOM48_RS04140 (GOM48_04120)	lepA	819812..821635 (+)	1824	WP_125399597.1	translation elongation factor 4	-
GOM48_RS04145 (GOM48_04125)	dprA/cilB/dalA	821802..822650 (+)	849	WP_235098528.1	DNA-processing protein DprA	Machinery gene
GOM48_RS04150 (GOM48_04130)	topA	822768..824855 (+)	2088	WP_235098529.1	type I DNA topoisomerase	-
GOM48_RS04155 (GOM48_04135)	-	824962..825321 (+)	360	WP_061420861.1	YbaN family protein	-
GOM48_RS04160 (GOM48_04140)	-	825415..826047 (+)	633	WP_235098531.1	copper homeostasis protein CutC	-
GOM48_RS04165 (GOM48_04145)	-	826091..826747 (+)	657	WP_235098533.1	MmcQ/YjbR family DNA-binding protein	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31180.65 Da
• Isoelectric Point: 4.9345

>NTDB_id=404916 GOM48_RS04145 WP_235098528.1 821802..822650(+) (dprA/cilB/dalA) [Streptococcus oralis strain SOD]
MKITNYEIYKLRKAGLTNQQILTVLEYDETVDQELLLGDIAEISGCRNPAVFMERYFQIDDAQLEKEFQKFPSFSILDDC
YPWDLSEIYDAPALLFYKGNLDLLKFPKVAVVGSRSCSSQGAKSVQKVIQGLENELIVVSGLAKGIDTAAHMATLQNGGK
TIAVIGTGLDVFYPKANKRLQEYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEARMRSGSLITCERAMEE
GRDAFAIPGNILDGHSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=404916 GOM48_RS04145 WP_235098528.1 821802..822650(+) (dprA/cilB/dalA) [Streptococcus oralis strain SOD]
ATGAAGATCACAAACTATGAGATTTACAAATTGCGCAAAGCTGGACTGACCAATCAACAGATTTTAACTGTTCTTGAATA
TGACGAGACTGTAGATCAGGAGCTCTTGCTAGGTGATATTGCTGAAATATCTGGGTGCCGTAATCCTGCTGTCTTTATGG
AACGCTATTTCCAGATAGATGATGCACAGTTGGAGAAGGAGTTCCAAAAATTTCCATCCTTTTCTATTCTTGATGACTGT
TATCCTTGGGATCTGAGTGAGATTTATGATGCTCCAGCGCTCTTATTTTATAAAGGAAATCTAGACTTATTGAAATTTCC
AAAGGTTGCTGTTGTAGGGAGTCGTTCATGTTCGAGTCAGGGAGCAAAGTCGGTTCAGAAAGTCATTCAAGGTTTGGAAA
ACGAGTTAATCGTGGTCAGTGGTTTGGCCAAAGGAATTGATACCGCTGCCCATATGGCTACACTCCAAAATGGTGGAAAA
ACGATTGCTGTGATTGGAACAGGATTGGATGTATTTTATCCTAAAGCCAATAAACGCTTGCAGGAGTACATTGGCAATGA
TCATCTGGTTCTCAGCGAATATGGACCTGGCGAGCAACCTCTGAAATTTCATTTTCCAGCTCGAAATCGTATCATAGCAG
GACTTTGTCGTGGGGTTATTGTAGCAGAGGCAAGGATGCGTTCAGGCAGTCTCATCACCTGTGAGCGTGCTATGGAGGAA
GGGCGCGATGCCTTTGCTATTCCAGGAAACATTTTAGATGGCCATTCAGATGGCTGTCACCACCTGATCCAAGAGGGAGC
AAAACTGGTCACAAGTGGGCAAGATGTACTAGCAGAGTTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	93.262	100	0.933
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	92.908	100	0.929
dprA/cilB/dalA	Streptococcus pneumoniae D39	92.908	100	0.929
dprA/cilB/dalA	Streptococcus pneumoniae R6	92.908	100	0.929
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	92.908	100	0.929
dprA/cilB/dalA	Streptococcus mitis SK321	92.199	100	0.922
dprA	Streptococcus mutans UA159	61.429	99.291	0.61
dprA	Lactococcus lactis subsp. cremoris KW2	55	99.291	0.546