Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GOM48_RS03610 Genome accession   NZ_CP046523
Coordinates   721150..721890 (+) Length   246 a.a.
NCBI ID   WP_235098430.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 716150..726890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS03600 (GOM48_03580) - 716978..719503 (+) 2526 WP_235098426.1 MBL fold metallo-hydrolase -
  GOM48_RS03605 (GOM48_03585) - 719549..721027 (-) 1479 WP_235098427.1 oligosaccharide flippase family protein -
  GOM48_RS03610 (GOM48_03590) mecA 721150..721890 (+) 741 WP_235098430.1 adaptor protein MecA Regulator
  GOM48_RS03615 (GOM48_03595) - 722038..723324 (+) 1287 WP_235098432.1 homoserine dehydrogenase -
  GOM48_RS03620 (GOM48_03600) thrB 723326..724195 (+) 870 WP_235098434.1 homoserine kinase -
  GOM48_RS03625 (GOM48_03605) msrB 724295..725233 (+) 939 WP_235098436.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28576.44 Da        Isoelectric Point: 4.1335

>NTDB_id=404914 GOM48_RS03610 WP_235098430.1 721150..721890(+) (mecA) [Streptococcus oralis strain SOD]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAKMSPDEFLKTLEKSIAEKTKDDIEAIQSLEQVEAKEEEQEQTEKESENKKEPYIYYILRFV
NLADLVAFAKTVTFEMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLG
LQKIHS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=404914 GOM48_RS03610 WP_235098430.1 721150..721890(+) (mecA) [Streptococcus oralis strain SOD]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGAGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAACTGGAAATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTTCGTGTGACGCCAAAACCAGATAAGGTTGATGTCTTTGTGACCAAGTCCAAGATT
GACCAGAATCTGGATTTTGAAGATTTGGCGGATTTACCAGACATGGAAGAATTGGCCAAAATGTCTCCGGATGAATTTCT
CAAAACGCTAGAAAAGAGTATCGCAGAGAAAACCAAGGATGATATTGAGGCTATTCAATCCCTAGAACAGGTAGAAGCTA
AGGAAGAAGAGCAAGAGCAGACAGAAAAGGAGTCGGAGAATAAGAAAGAACCTTATATCTACTATATCCTGCGTTTCGTG
AATCTTGCAGACCTAGTGGCTTTTGCTAAAACAGTGACTTTTGAGATGGAAACATCTGAACTCTATAAGATGAATGGACA
CTATTATTTAACAATCTTAGTCGATGTAGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAAT
TTGCAGACGACAGTGACATCAGTCGTTCAGTCTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTCGGT
CTGCAAAAGATTCATTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

90.574

99.187

0.898
  mecA Streptococcus pneumoniae D39

90.574

99.187

0.898
  mecA Streptococcus pneumoniae R6

90.574

99.187

0.898
  mecA Streptococcus pneumoniae TIGR4

90.164

99.187

0.894
  mecA Streptococcus mutans UA159

49.59

99.187

0.492
  mecA Streptococcus thermophilus LMD-9

47.39

100

0.48
  mecA Streptococcus thermophilus LMG 18311

46.988

100

0.476

Multiple sequence alignment