Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   GE024_RS08170 Genome accession   NZ_CP046521
Coordinates   1631790..1633685 (-) Length   631 a.a.
NCBI ID   WP_093998978.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1626790..1638685
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS08140 (GE024_08180) tnpA 1626888..1627352 (-) 465 Protein_1550 IS200/IS605 family transposase -
  GE024_RS08145 (GE024_08185) - 1627540..1627899 (-) 360 WP_093998981.1 S1 RNA-binding domain-containing protein -
  GE024_RS08150 (GE024_08190) - 1627899..1629299 (-) 1401 WP_093998980.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GE024_RS08155 (GE024_08195) - 1629336..1629977 (-) 642 WP_003044709.1 response regulator transcription factor -
  GE024_RS08160 (GE024_08200) - 1629970..1630974 (-) 1005 WP_003044712.1 sensor histidine kinase -
  GE024_RS08165 (GE024_08205) liaF 1630971..1631663 (-) 693 WP_093998979.1 cell wall-active antibiotics response protein LiaF -
  GE024_RS08170 (GE024_08210) pknB 1631790..1633685 (-) 1896 WP_093998978.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GE024_RS08175 (GE024_08215) - 1633682..1634422 (-) 741 WP_003044720.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  GE024_RS08180 (GE024_08220) rsmB 1634460..1635782 (-) 1323 WP_093998977.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  GE024_RS08185 (GE024_08225) fmt 1635772..1636707 (-) 936 WP_093998976.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68841.17 Da        Isoelectric Point: 6.9928

>NTDB_id=404868 GE024_RS08170 WP_093998978.1 1631790..1633685(-) (pknB) [Streptococcus canis strain HL_100]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGADLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKNGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENHNVP
QALENVVIRATAKKLSDRYGSTFEMSRDLMTALSYNRSRERKVIFDDVESTKPLPKVTPTPMTTPKVAPTPVTSTTESRL
EQTNQMDTLQKPQKKKRNGRFLGTLLKILFSLFIVGVALFTYLVLTKPTSVKVPDVTGASLKVAKQELQDLGLKVGKVRQ
IESDTVAEGNVVRTDPQAGTAKRKGSSVTVYLSIGNKGFEMENYKGVDYQDAMNSLMETYGIPKSKIKIERIVTNEYPEN
TVISQSPSVGDKFNPNGKSKITLSVAVSDTVIMPMVTEYSYADAVNTLTALGIDASRIKAYAPSSSSATGFIQVNSPSSK
AIVSGQMPYYGTTLSLSEKGEISLYLYPEETHSSSSSSSSESSSSSSSTSDGTGTSSNTELNPSESTGQTP

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=404868 GE024_RS08170 WP_093998978.1 1631790..1633685(-) (pknB) [Streptococcus canis strain HL_100]
ATGATTCAGATTGGCAAGTTATTTGCTGGTCGTTATCGTATTCTAAAGTCTATTGGCCGCGGTGGTATGGCGGATGTTTA
TTTGGCAAATGATTTGATCTTGGATAATGAAGACGTTGCAATCAAAGTTTTGCGTACCAATTATCAAACAGATCAGGTGG
CAGTTGCGCGTTTCCAACGGGAAGCGCGGGCCATGGCTGAATTGAATCATCCGAATATTGTTGCCATCCGGGATATAGGT
GAAGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGTGCTGACCTAAAGAAGTACATTCAAGATCATGCACC
GCTATCCAATAACGAAGTGGTTAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCTCACCAAAAAGGAATTGTGC
ATAGGGATTTAAAACCTCAAAACATTCTCTTAACTAAAAATGGTGTGGTTAAGGTGACTGACTTTGGGATTGCTGTTGCC
TTTGCAGAAACGAGTTTGACTCAGACCAACTCGATGTTAGGTAGTGTGCATTATTTGTCTCCGGAGCAGGCTCGTGGTTC
AAAGGCAACTATCCAAAGTGACATTTATGCGATGGGGATTATGCTCTTTGAAATGCTGACAGGGCATATTCCTTATGACG
GTGACAGTGCTGTTACGATTGCCTTGCAACATTTTCAAAAGCCTCTTCCGTCTATTATTGACGAAAATCACAATGTGCCG
CAAGCTTTAGAGAATGTTGTTATCCGAGCAACAGCCAAGAAATTGAGTGATCGTTATGGGTCCACTTTTGAGATGAGCCG
TGACTTGATGACGGCGCTTAGCTACAACCGTAGCCGTGAACGTAAAGTCATTTTTGATGATGTGGAAAGCACTAAGCCGC
TTCCCAAAGTAACCCCAACGCCAATGACAACACCAAAAGTTGCGCCGACTCCAGTTACTTCAACAACTGAAAGTAGATTA
GAGCAAACCAATCAAATGGACACGCTCCAAAAGCCACAAAAAAAGAAAAGAAATGGTCGTTTTTTAGGAACCTTATTGAA
GATTCTTTTTTCTCTCTTTATTGTGGGGGTGGCTCTTTTTACTTATTTGGTATTAACTAAGCCAACTTCTGTGAAAGTTC
CTGATGTAACAGGTGCTAGCTTGAAAGTAGCTAAGCAAGAACTACAAGATCTTGGTCTAAAAGTAGGAAAGGTGCGGCAA
ATTGAAAGCGATACTGTCGCTGAAGGAAATGTTGTCCGAACAGACCCACAAGCAGGAACAGCTAAGCGTAAAGGATCAAG
TGTAACTGTTTATTTGTCAATCGGAAATAAAGGTTTTGAAATGGAAAACTACAAAGGGGTTGATTATCAAGATGCTATGA
ACAGCTTGATGGAAACCTATGGCATTCCAAAATCTAAGATTAAAATTGAGCGTATTGTGACCAATGAGTATCCTGAAAAT
ACTGTTATTAGCCAGTCACCAAGTGTAGGAGATAAGTTTAACCCCAATGGTAAATCTAAAATTACCCTTAGCGTAGCCGT
TAGTGACACAGTCATTATGCCAATGGTTACAGAATATAGTTATGCTGATGCGGTTAATACTTTGACAGCACTGGGTATTG
ATGCCTCTAGGATAAAAGCTTATGCGCCAAGTTCAAGTTCAGCAACTGGTTTTATTCAGGTTAATTCCCCTAGTTCAAAA
GCTATTGTTAGTGGACAGATGCCTTATTATGGTACGACATTGAGTCTTTCTGAAAAAGGAGAGATAAGCCTTTATCTTTA
TCCAGAAGAAACACACTCTTCAAGTAGTTCCTCAAGTTCAGAATCAAGTTCAAGTAGTTCCTCAACAAGTGATGGCACTG
GGACAAGTAGCAATACCGAATTAAACCCGTCAGAATCGACTGGACAAACACCTTGA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-233)

PASTA domain (PASTA)

(371-433)

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(511-587)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.529

92.868

0.609
  stkP/pknB Streptococcus salivarius strain HSISS4

62.203

93.502

0.582
  stkP Streptococcus pneumoniae TIGR4

58.221

81.933

0.477
  stkP Streptococcus pneumoniae D39

57.803

82.25

0.475
  stkP Streptococcus pneumoniae R6

57.803

82.25

0.475
  stkP Streptococcus pneumoniae Rx1

57.834

81.933

0.474

Multiple sequence alignment