Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GE024_RS01820 Genome accession   NZ_CP046521
Coordinates   339272..340033 (+) Length   253 a.a.
NCBI ID   WP_093999421.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 334272..345033
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS01795 (GE024_01790) - 334324..335214 (+) 891 WP_156667671.1 SPFH domain-containing protein -
  GE024_RS01800 (GE024_01795) - 335353..335469 (-) 117 WP_003046630.1 putative metal homeostasis protein -
  GE024_RS01805 (GE024_01800) - 335611..336351 (-) 741 WP_093999490.1 amino acid ABC transporter ATP-binding protein -
  GE024_RS01810 (GE024_01805) - 336344..337912 (-) 1569 WP_093999489.1 ABC transporter substrate-binding protein/permease -
  GE024_RS01815 (GE024_01810) - 338290..339129 (+) 840 WP_003046638.1 undecaprenyl-diphosphate phosphatase -
  GE024_RS01820 (GE024_01815) mecA 339272..340033 (+) 762 WP_093999421.1 adaptor protein MecA Regulator
  GE024_RS01825 (GE024_01820) - 340040..341209 (+) 1170 WP_093999420.1 glycosyltransferase family 4 protein -
  GE024_RS01830 (GE024_01825) sufC 341333..342103 (+) 771 WP_003046647.1 Fe-S cluster assembly ATPase SufC -
  GE024_RS01835 (GE024_01830) sufD 342202..343464 (+) 1263 WP_093999419.1 Fe-S cluster assembly protein SufD -
  GE024_RS01840 (GE024_01835) - 343495..344721 (+) 1227 WP_093999418.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29130.90 Da        Isoelectric Point: 4.1236

>NTDB_id=404839 GE024_RS01820 WP_093999421.1 339272..340033(+) (mecA) [Streptococcus canis strain HL_100]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEL
NKELNFEDLADLGDISQMTPEDFFKSLEQSMREKGDVNAHEKLEKIEEIMEDVVEATLTGQAEATDETHEVDLEPLDYVH
YVLDFDTLPEAITFAKTIDFPIEASELYKGASRYHMTILLDVQQQPSYFANVMYARLIEYATPGSKTRAYLQEHGLQLIL
GGAVEQLRKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=404839 GE024_RS01820 WP_093999421.1 339272..340033(+) (mecA) [Streptococcus canis strain HL_100]
ATGGAAATGAAACAAATTAGCGAGACAACGCTGAAAATAACAATTAGTATGGATGATTTAGAAGAAAGAGGAATGGAGTT
AAAAGATTTTCTCATTCCCCAAGAAAAAACGGAAGAGTTCTTTTATTCTGTTATGGATGAACTAGATCTTCCAGATAATT
TTAAAGATAGTGGCATGCTTAGTTTTCGAGTAACACCAAGAAAAGACCGGCTAGATGTTTTTGTAACCAAATCTGAGCTT
AATAAGGAGCTTAACTTTGAAGATTTGGCAGATTTGGGTGATATTTCTCAAATGACACCTGAAGATTTTTTCAAAAGTTT
GGAGCAATCCATGCGTGAAAAAGGGGATGTCAATGCGCATGAGAAATTGGAAAAAATTGAAGAAATCATGGAAGACGTGG
TCGAAGCAACCTTAACTGGTCAGGCTGAGGCAACAGATGAAACGCATGAGGTCGATCTAGAACCATTGGATTATGTGCAC
TATGTTTTGGACTTTGATACCCTTCCAGAGGCGATAACCTTCGCCAAAACCATTGATTTCCCTATTGAAGCTTCAGAATT
ATACAAGGGTGCCAGCCGTTACCACATGACCATTTTATTGGACGTTCAACAGCAGCCGTCATATTTTGCGAATGTTATGT
ATGCAAGGTTAATTGAGTATGCAACCCCTGGGTCAAAAACAAGAGCCTACTTGCAAGAGCATGGCTTACAATTGATTCTA
GGTGGCGCTGTTGAGCAATTACGAAAAATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.6

98.814

0.628
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.823

98.419

0.549
  mecA Streptococcus pneumoniae TIGR4

48.221

100

0.482
  mecA Streptococcus pneumoniae Rx1

47.826

100

0.478
  mecA Streptococcus pneumoniae D39

47.826

100

0.478
  mecA Streptococcus pneumoniae R6

47.826

100

0.478

Multiple sequence alignment