Detailed information NTG0403284

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: GL186_RS09830
• Genome accession: NZ_CP046358
• Coordinates: 1914943..1915404 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 566
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1909943..1920404

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL186_RS09800 (GL186_09970)	-	1910256..1911080 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
GL186_RS09805 (GL186_09975)	rnpA	1911055..1911426 (-)	372	WP_000739247.1	ribonuclease P protein component	-
GL186_RS11380	-	1911443..1911574 (-)	132	WP_000768904.1	hypothetical protein	-
GL186_RS09810 (GL186_09980)	-	1911575..1912765 (-)	1191	WP_000167765.1	acetate kinase	-
GL186_RS09815 (GL186_09985)	comYH	1912816..1913769 (-)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
GL186_RS09820 (GL186_09995)	-	1913830..1914417 (-)	588	WP_000679779.1	class I SAM-dependent methyltransferase	-
GL186_RS09825 (GL186_10000)	comGG/cglG	1914573..1914965 (-)	393	WP_001818028.1	competence type IV pilus minor pilin ComGG	Machinery gene
GL186_RS09830 (GL186_10005)	comGF/cglF	1914943..1915404 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
GL186_RS09835 (GL186_10010)	comGE/cglE	1915367..1915669 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
GL186_RS09840 (GL186_10015)	comGD/cglD	1915632..1916036 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
GL186_RS09845 (GL186_10020)	comGC/cglC	1916029..1916355 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
GL186_RS09850 (GL186_10025)	comGB/cglB	1916357..1917373 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
GL186_RS09855 (GL186_10030)	comGA/cglA/cilD	1917321..1918262 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
GL186_RS09860 (GL186_10035)	-	1918337..1918702 (-)	366	WP_000286415.1	DUF1033 family protein	-
GL186_RS09865 (GL186_10040)	-	1918853..1919911 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=403284 GL186_RS09830 WP_000250539.1 1914943..1915404(-) (comGF/cglF) [Streptococcus pneumoniae strain 566]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=403284 GL186_RS09830 WP_000250539.1 1914943..1915404(-) (comGF/cglF) [Streptococcus pneumoniae strain 566]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915