Detailed information NTG0403285

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: HUS69_RS21355
• Genome accession: NZ_CP056073
• Coordinates: 4454001..4455026 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain EC50
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4449001..4460026

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUS69_RS21330 (HUS69_21350)	metJ	4449438..4449755 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
HUS69_RS21335 (HUS69_21355)	yiiX	4449939..4450547 (+)	609	WP_000797341.1	YiiX family permuted papain-like enzyme	-
HUS69_RS21340 (HUS69_21360)	-	4450554..4451177 (+)	624	WP_000720774.1	TIGR02117 family protein	-
HUS69_RS21345 (HUS69_21365)	rpmE	4451232..4451444 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
HUS69_RS21350 (HUS69_21370)	priA	4451647..4453845 (+)	2199	WP_001300388.1	primosomal protein N'	Machinery gene
HUS69_RS21355 (HUS69_21375)	cytR	4454001..4455026 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
HUS69_RS21360 (HUS69_21380)	ftsN	4455118..4456077 (+)	960	WP_000068828.1	cell division protein FtsN	-
HUS69_RS21365 (HUS69_21385)	hslV	4456170..4456700 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
HUS69_RS21370 (HUS69_21390)	hslU	4456710..4458041 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
HUS69_RS21375 (HUS69_21395)	menA	4458108..4459034 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
HUS69_RS21380 (HUS69_21400)	rraA	4459127..4459612 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
HUS69_RS21385 (HUS69_21405)	zapB	4459697..4459942 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=403285 HUS69_RS21355 WP_000644904.1 4454001..4455026(+) (cytR) [Escherichia coli strain EC50]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=403285 HUS69_RS21355 WP_000644904.1 4454001..4455026(+) (cytR) [Escherichia coli strain EC50]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628