Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   GL186_RS09835 Genome accession   NZ_CP046358
Coordinates   1915367..1915669 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 566     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1910367..1920669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL186_RS09805 (GL186_09975) rnpA 1911055..1911426 (-) 372 WP_000739247.1 ribonuclease P protein component -
  GL186_RS11380 - 1911443..1911574 (-) 132 WP_000768904.1 hypothetical protein -
  GL186_RS09810 (GL186_09980) - 1911575..1912765 (-) 1191 WP_000167765.1 acetate kinase -
  GL186_RS09815 (GL186_09985) comYH 1912816..1913769 (-) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  GL186_RS09820 (GL186_09995) - 1913830..1914417 (-) 588 WP_000679779.1 class I SAM-dependent methyltransferase -
  GL186_RS09825 (GL186_10000) comGG/cglG 1914573..1914965 (-) 393 WP_001818028.1 competence type IV pilus minor pilin ComGG Machinery gene
  GL186_RS09830 (GL186_10005) comGF/cglF 1914943..1915404 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  GL186_RS09835 (GL186_10010) comGE/cglE 1915367..1915669 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  GL186_RS09840 (GL186_10015) comGD/cglD 1915632..1916036 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  GL186_RS09845 (GL186_10020) comGC/cglC 1916029..1916355 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  GL186_RS09850 (GL186_10025) comGB/cglB 1916357..1917373 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  GL186_RS09855 (GL186_10030) comGA/cglA/cilD 1917321..1918262 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  GL186_RS09860 (GL186_10035) - 1918337..1918702 (-) 366 WP_000286415.1 DUF1033 family protein -
  GL186_RS09865 (GL186_10040) - 1918853..1919911 (-) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=403285 GL186_RS09835 WP_000413382.1 1915367..1915669(-) (comGE/cglE) [Streptococcus pneumoniae strain 566]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=403285 GL186_RS09835 WP_000413382.1 1915367..1915669(-) (comGE/cglE) [Streptococcus pneumoniae strain 566]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment