Detailed information NTG0403066

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: GL183_RS10895
• Genome accession: NZ_CP046355
• Coordinates: 2127628..2128977 (-)
• Length: 449 a.a.
• NCBI ID: WP_024477962.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 475
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2122628..2133977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL183_RS10885 (GL183_11020)	-	2122969..2126694 (-)	3726	WP_024477961.1	phosphoribosylformylglycinamidine synthase	-
GL183_RS10890 (GL183_11025)	purC	2126751..2127458 (-)	708	WP_000043301.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
GL183_RS10895 (GL183_11030)	comB	2127628..2128977 (-)	1350	WP_024477962.1	competence pheromone export protein ComB	Regulator
GL183_RS10900 (GL183_11035)	comA	2128990..2131143 (-)	2154	WP_000668280.1	peptide cleavage/export ABC transporter ComA	Regulator
GL183_RS10905 (GL183_11040)	-	2131523..2132014 (-)	492	WP_000671990.1	hypothetical protein	-
GL183_RS10910 (GL183_11045)	-	2131995..2132591 (-)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
GL183_RS10915 (GL183_11050)	-	2132588..2133070 (-)	483	WP_001232094.1	stage II sporulation protein M	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 49481.34 Da
• Isoelectric Point: 5.5618

>NTDB_id=403066 GL183_RS10895 WP_024477962.1 2127628..2128977(-) (comB) [Streptococcus pneumoniae strain 475]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQGGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide

• Length: 1350 bp

>NTDB_id=403066 GL183_RS10895 WP_024477962.1 2127628..2128977(-) (comB) [Streptococcus pneumoniae strain 475]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGGAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAAGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATTTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAGTTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTATGGGGTGGAAGGCCG
TTTACAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus pneumoniae TIGR4	99.555	100	0.996
comB	Streptococcus pneumoniae Rx1	98.886	100	0.989
comB	Streptococcus pneumoniae D39	98.886	100	0.989
comB	Streptococcus pneumoniae R6	98.886	100	0.989
comB	Streptococcus mitis SK321	94.655	100	0.947
comB	Streptococcus mitis NCTC 12261	94.209	100	0.942
comB	Streptococcus gordonii str. Challis substr. CH1	55.333	100	0.555