Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   HVV27_RS00625 Genome accession   NZ_CP055246
Coordinates   101692..102120 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY767     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 96692..107120
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HVV27_RS00605 (HVV27_00600) - 99023..99388 (+) 366 WP_002986560.1 DUF1033 family protein -
  HVV27_RS00610 (HVV27_00605) comGA 99481..100419 (+) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  HVV27_RS00615 (HVV27_00610) comGB 100355..101389 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  HVV27_RS00620 (HVV27_00615) comGC 101391..101717 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  HVV27_RS00625 (HVV27_00620) comGD 101692..102120 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  HVV27_RS00630 (HVV27_00625) comGE 102077..102361 (+) 285 WP_011528162.1 competence type IV pilus minor pilin ComGE Machinery gene
  HVV27_RS00635 (HVV27_00630) comGF 102354..102788 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  HVV27_RS00640 (HVV27_00635) comGG 102772..103098 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  HVV27_RS00645 (HVV27_00640) comGH 103196..104149 (+) 954 WP_021299429.1 class I SAM-dependent methyltransferase Machinery gene
  HVV27_RS00650 (HVV27_00645) - 104208..105404 (+) 1197 WP_011528164.1 acetate kinase -
  HVV27_RS00655 (HVV27_00650) - 105591..105899 (+) 309 WP_011528165.1 hypothetical protein -
  HVV27_RS00660 (HVV27_00655) proC 105982..106752 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=402798 HVV27_RS00625 WP_002986548.1 101692..102120(+) (comGD) [Streptococcus pyogenes strain TSPY767]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=402798 HVV27_RS00625 WP_002986548.1 101692..102120(+) (comGD) [Streptococcus pyogenes strain TSPY767]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366