Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   FOB91_RS06720 Genome accession   NZ_CP046328
Coordinates   1365130..1366491 (-) Length   453 a.a.
NCBI ID   WP_012131078.1    Uniprot ID   P95767
Organism   Streptococcus gordonii strain FDAARGOS_683     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1360130..1371491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB91_RS06695 (FOB91_06695) pth 1362286..1362855 (-) 570 WP_012131076.1 aminoacyl-tRNA hydrolase -
  FOB91_RS06700 (FOB91_06700) ychF 1362929..1364044 (-) 1116 WP_012131077.1 redox-regulated ATPase YchF -
  FOB91_RS06715 (FOB91_06715) comE/comE2 1364366..1365133 (-) 768 WP_008808031.1 competence system response regulator transcription factor ComE Regulator
  FOB91_RS06720 (FOB91_06720) comD/comD1 1365130..1366491 (-) 1362 WP_012131078.1 competence system sensor histidine kinase ComD Regulator
  FOB91_RS06725 (FOB91_06725) comC/comC1 1366507..1366659 (-) 153 WP_012131079.1 bacteriocin Regulator
  FOB91_RS06735 (FOB91_06735) rlmH 1366945..1367424 (-) 480 WP_012131080.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  FOB91_RS06740 (FOB91_06740) htrA 1367618..1368811 (+) 1194 WP_012131081.1 S1C family serine protease Regulator
  FOB91_RS06745 (FOB91_06745) spo0J 1368877..1369641 (+) 765 WP_012131082.1 ParB/RepB/Spo0J family partition protein Regulator
  FOB91_RS06750 (FOB91_06750) dnaA 1369844..1371196 (+) 1353 WP_011999558.1 chromosomal replication initiator protein DnaA -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 53636.59 Da        Isoelectric Point: 6.4089

>NTDB_id=402704 FOB91_RS06720 WP_012131078.1 1365130..1366491(-) (comD/comD1) [Streptococcus gordonii strain FDAARGOS_683]
MIFTIILSLFPVIIQVFSYDFFYNKINRKKKINIKLIILFWGLIMVISFLYSLFLLLPDYWKIFRDIFHYLFLLIQPLIF
YKYFLIKRKEYENYLNLFLSFVIYLSVETSETFLSVIISSITGDSFVKQHYDIFYIIINLLSLFIILKVVDFFDFYFEYY
KEPIYKNDLYNVNKSYIVIHILLNISHWFSENAHLNSFASMIATIGFIMFLSTLFYLKSAREQYEKAKEIQQKKEEQRQL
QLYTDEIVGLYNEIRGFRHDYAGMLTSLQTGINSGDMKEVERIFHNVLSQANISLRSDDYTFFELNNVQDTALRSVLIQT
IFKARECGVEIVFEMKDVIETLPMKLLDLVRVASVLLNNAVEGAAESPSKTMNVSLVKLDKEIVFVIQNSRQSRYINLEE
IYEVGFSTKGENRGLGLNNVKEIIDKYDEVILETDIETNYFIQVVRFKRKEKI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=402704 FOB91_RS06720 WP_012131078.1 1365130..1366491(-) (comD/comD1) [Streptococcus gordonii strain FDAARGOS_683]
ATGATATTTACAATAATACTGTCTTTATTTCCAGTTATAATACAAGTTTTTTCCTATGATTTTTTTTACAATAAAATTAA
TAGAAAAAAGAAAATTAATATTAAACTCATTATTCTATTTTGGGGTTTAATAATGGTAATATCATTTCTTTATTCTCTAT
TCTTATTATTACCAGATTATTGGAAAATTTTTCGAGATATTTTTCATTATTTATTTTTACTTATTCAGCCTCTTATTTTC
TACAAATATTTTCTTATTAAAAGAAAAGAGTATGAAAATTACTTGAATTTGTTTTTATCGTTTGTTATCTATTTATCTGT
GGAGACTTCTGAAACTTTTTTATCTGTCATTATTTCTTCAATAACAGGAGATTCTTTTGTAAAACAACATTATGATATTT
TTTACATTATAATTAATCTTTTATCTTTGTTTATTATTTTAAAGGTTGTTGATTTTTTTGACTTTTATTTTGAGTACTAT
AAAGAACCAATTTATAAAAATGATCTATATAATGTTAATAAGTCATATATAGTAATCCATATCCTATTAAATATTTCTCA
TTGGTTCAGCGAAAATGCACATCTTAATAGCTTTGCTAGTATGATTGCAACTATAGGATTTATTATGTTTTTGTCGACTT
TATTTTATCTGAAGTCTGCTCGTGAACAATATGAAAAAGCTAAAGAAATTCAGCAAAAAAAGGAAGAACAAAGACAACTA
CAACTTTATACAGATGAAATTGTAGGTCTTTATAACGAAATTCGAGGTTTTCGTCACGATTATGCTGGTATGTTAACAAG
TTTGCAAACCGGAATTAACTCAGGTGATATGAAAGAAGTAGAGCGAATCTTTCATAATGTTTTAAGTCAAGCTAATATTT
CCCTTCGATCAGATGACTATACTTTTTTTGAGTTAAATAATGTTCAAGACACTGCCTTGAGAAGTGTGTTAATTCAAACT
ATATTTAAGGCTCGAGAGTGTGGAGTAGAGATCGTATTTGAAATGAAGGATGTTATTGAGACATTACCTATGAAACTTTT
AGATTTAGTTCGAGTAGCTAGTGTATTGCTCAATAATGCAGTTGAAGGGGCAGCTGAAAGTCCCTCAAAAACAATGAACG
TGTCTTTAGTAAAGCTAGATAAAGAAATTGTTTTTGTAATTCAGAATTCTCGTCAAAGCCGTTACATTAATTTAGAAGAA
ATTTATGAAGTAGGCTTCTCAACAAAAGGAGAAAATCGAGGATTAGGTTTAAATAATGTCAAAGAAATTATTGACAAATA
TGATGAAGTTATTCTGGAAACAGATATAGAAACAAATTATTTTATACAAGTTGTAAGATTTAAAAGAAAGGAAAAAATAT
GA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(344-445)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P95767

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

100

100

1
  comD/comD2 Streptococcus gordonii strain NCTC7865

89.845

100

0.898
  comD/comD2 Streptococcus pneumoniae TIGR4

47.17

93.598

0.442
  comD/comD1 Streptococcus pneumoniae D39

47.17

93.598

0.442
  comD/comD1 Streptococcus pneumoniae R6

47.17

93.598

0.442
  comD/comD1 Streptococcus pneumoniae Rx1

47.17

93.598

0.442
  comD Streptococcus mitis SK321

46.682

93.157

0.435
  comD Streptococcus mitis NCTC 12261

45.647

93.819

0.428

Multiple sequence alignment