Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   FOB91_RS06470 Genome accession   NZ_CP046328
Coordinates   1330780..1332138 (-) Length   452 a.a.
NCBI ID   WP_012131059.1    Uniprot ID   P95761
Organism   Streptococcus gordonii strain FDAARGOS_683     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1325780..1337138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB91_RS06455 (FOB91_06455) - 1326255..1327448 (-) 1194 WP_012131054.1 ATP-grasp domain-containing protein -
  FOB91_RS06460 (FOB91_06460) purD 1327508..1328767 (-) 1260 WP_012131055.1 phosphoribosylamine--glycine ligase -
  FOB91_RS06465 (FOB91_06465) lytF 1329012..1330661 (+) 1650 WP_012131057.1 GBS Bsp-like repeat-containing protein Regulator
  FOB91_RS06470 (FOB91_06470) comB 1330780..1332138 (-) 1359 WP_012131059.1 competence pheromone export protein ComB Regulator
  FOB91_RS06475 (FOB91_06475) comA 1332148..1334301 (-) 2154 WP_012131060.1 peptide cleavage/export ABC transporter ComA Regulator
  FOB91_RS06480 (FOB91_06480) rpsD 1334755..1335366 (-) 612 WP_008810013.1 30S ribosomal protein S4 -
  FOB91_RS06485 (FOB91_06485) - 1335632..1336354 (-) 723 WP_008810014.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 49879.14 Da        Isoelectric Point: 6.0163

>NTDB_id=402700 FOB91_RS06470 WP_012131059.1 1330780..1332138(-) (comB) [Streptococcus gordonii strain FDAARGOS_683]
MNEQFLESAEFYQKRYHNFASCLIVPSLILLVFLVGFSMLAKKEITISSRASVEASRVLAQIQSTSNQPIIANHLAENKE
VKKGELLIQYAVEGEGAQEQKFSSQLDLLKDQKGKLETLRSSLESGRNQFTEPDSYGYEQSFKDYQNQVESMTSSVNQQN
ATIASQNAAASQSQAELGGVISDVDSKLNDHRNLKNAIQSGVGIDASHPLHSLYQSYRDQLSLAEDKATAQSQIVAQLDG
QISQLEATAATYRVQYAGAGAQQAYASNLSSQLASLKAQYLVKVGQELTTLTQQILEAESNLKLQETVSKRGQILAEMDG
LLHLNPEVQGSTLVAEGTALAQIYPKITNERKIKIVTYVSSKDVSTIKNGDKVRFITADDANKQMILTSQISSIDANATQ
TKQGNFFKVECEMAVSKDQAKKLRYGLEGKFVMVTGEKTYFSYYMEKFFNLG

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=402700 FOB91_RS06470 WP_012131059.1 1330780..1332138(-) (comB) [Streptococcus gordonii strain FDAARGOS_683]
ATGAATGAACAATTTTTAGAAAGTGCAGAGTTTTATCAGAAACGTTATCATAATTTTGCTAGTTGTTTAATTGTGCCAAG
TCTTATTTTACTAGTATTTCTAGTTGGTTTTTCCATGCTGGCTAAAAAAGAAATTACGATTTCTAGCCGTGCTTCTGTAG
AAGCTAGCCGAGTGCTAGCTCAGATTCAGTCGACTAGTAACCAGCCTATCATTGCGAATCATTTGGCAGAAAACAAGGAG
GTCAAAAAAGGGGAGTTGCTAATCCAGTATGCAGTAGAAGGAGAGGGAGCTCAGGAACAGAAGTTTTCCAGCCAGCTTGA
CTTACTCAAAGATCAAAAGGGCAAACTAGAAACTTTGCGTTCCAGTTTAGAAAGCGGGCGTAATCAATTTACTGAGCCAG
ATAGTTATGGCTACGAACAAAGCTTTAAAGACTACCAAAATCAAGTAGAGAGTATGACTAGTTCTGTGAATCAGCAAAAT
GCTACGATTGCTTCACAAAATGCAGCGGCCAGTCAGTCTCAGGCGGAACTGGGCGGTGTTATCAGTGATGTGGATAGCAA
ACTAAATGACCATCGAAACTTGAAAAATGCCATTCAAAGTGGGGTGGGTATAGATGCATCGCACCCTCTTCACTCCTTGT
ACCAGTCCTATCGTGATCAGTTGAGCCTGGCGGAGGATAAGGCAACAGCTCAAAGTCAGATTGTAGCTCAGTTAGATGGG
CAAATCTCTCAATTAGAAGCAACAGCTGCGACTTATCGTGTCCAATATGCTGGTGCAGGCGCTCAACAAGCCTATGCTAG
CAATTTATCCAGTCAGTTGGCTTCACTGAAAGCCCAGTATCTGGTCAAGGTAGGACAAGAATTGACCACTCTGACTCAGC
AAATCTTGGAAGCCGAGAGCAATCTTAAACTTCAAGAAACAGTCTCTAAGCGAGGTCAGATTTTGGCTGAAATGGATGGC
TTGCTTCACTTAAATCCAGAAGTACAAGGATCTACTCTGGTGGCAGAAGGAACTGCTTTGGCTCAGATTTACCCCAAAAT
CACTAATGAAAGAAAAATCAAAATTGTCACATATGTTTCTTCCAAGGATGTATCTACTATTAAAAATGGAGACAAGGTGC
GCTTTATCACAGCTGATGATGCTAACAAACAAATGATTTTGACATCCCAAATTTCCAGTATTGATGCTAATGCTACCCAA
ACCAAACAGGGAAATTTCTTTAAAGTAGAATGCGAAATGGCTGTTAGTAAAGATCAAGCTAAGAAGCTCCGCTATGGCTT
GGAAGGTAAATTTGTCATGGTAACTGGGGAAAAGACTTATTTCAGCTATTATATGGAAAAATTTTTCAATCTTGGTTGA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(314-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P95761

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

100

100

1
  comB Streptococcus mitis NCTC 12261

55.778

99.558

0.555
  comB Streptococcus pneumoniae D39

55.556

99.558

0.553
  comB Streptococcus pneumoniae R6

55.556

99.558

0.553
  comB Streptococcus pneumoniae Rx1

55.556

99.558

0.553
  comB Streptococcus mitis SK321

55.111

99.558

0.549
  comB Streptococcus pneumoniae TIGR4

55.111

99.558

0.549

Multiple sequence alignment