Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   HUZ70_RS16985 Genome accession   NZ_CP055048
Coordinates   3586537..3587169 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain SWHEFF_58     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3581537..3592169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUZ70_RS16960 (HUZ70_16820) yhfG 3581670..3581837 (+) 168 WP_000736860.1 YhfG family protein -
  HUZ70_RS16965 (HUZ70_16825) fic 3581827..3582429 (+) 603 WP_001280645.1 putative adenosine monophosphate-protein transferase Fic -
  HUZ70_RS16970 (HUZ70_16830) pabA 3582461..3583024 (+) 564 WP_001551743.1 aminodeoxychorismate synthase component 2 -
  HUZ70_RS16975 (HUZ70_16835) argD 3583110..3584333 (+) 1224 WP_001551741.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  HUZ70_RS16980 (HUZ70_16840) yhfK 3584396..3586486 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  HUZ70_RS16985 (HUZ70_16845) crp 3586537..3587169 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  HUZ70_RS16990 (HUZ70_16850) yhfA 3587471..3587875 (+) 405 WP_001148908.1 OsmC family protein -
  HUZ70_RS16995 (HUZ70_16855) prkB 3587930..3588799 (-) 870 WP_001274680.1 phosphoribulokinase -
  HUZ70_RS17000 (HUZ70_16860) yheU 3588853..3589071 (-) 219 WP_000907085.1 YheU family protein -
  HUZ70_RS17005 (HUZ70_16865) yheT 3589065..3590087 (-) 1023 WP_001551740.1 hydrolase -
  HUZ70_RS17010 (HUZ70_16870) yheS 3590087..3592006 (-) 1920 WP_001551739.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=402675 HUZ70_RS16985 WP_000242755.1 3586537..3587169(-) (crp) [Escherichia coli strain SWHEFF_58]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=402675 HUZ70_RS16985 WP_000242755.1 3586537..3587169(-) (crp) [Escherichia coli strain SWHEFF_58]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGATGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment