Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SOR_RS07525 Genome accession   NC_015291
Coordinates   1493922..1495823 (-) Length   633 a.a.
NCBI ID   WP_000614524.1    Uniprot ID   F2QEX3
Organism   Streptococcus oralis Uo5     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1488922..1500823
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS07500 (SOR_1535) - 1489053..1490018 (+) 966 WP_000225986.1 LacI family DNA-binding transcriptional regulator -
  SOR_RS07505 (SOR_1536) - 1490054..1491328 (-) 1275 WP_000704362.1 hydroxymethylglutaryl-CoA reductase, degradative -
  SOR_RS07510 (SOR_1537) - 1491328..1492500 (-) 1173 WP_000151968.1 hydroxymethylglutaryl-CoA synthase -
  SOR_RS07515 (SOR_1538) - 1492619..1493074 (-) 456 WP_000176907.1 threonine/serine exporter family protein -
  SOR_RS07520 (SOR_1539) - 1493076..1493834 (-) 759 WP_000344541.1 threonine/serine exporter family protein -
  SOR_RS07525 (SOR_1540) stkP 1493922..1495823 (-) 1902 WP_000614524.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SOR_RS07530 (SOR_1541) - 1495820..1496560 (-) 741 WP_000401527.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SOR_RS07535 (SOR_1542) rsmB 1496576..1497889 (-) 1314 WP_013670271.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SOR_RS07540 (SOR_1543) fmt 1497882..1498817 (-) 936 WP_000163662.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 68866.14 Da        Isoelectric Point: 8.9709

>NTDB_id=40209 SOR_RS07525 WP_000614524.1 1493922..1495823(-) (stkP) [Streptococcus oralis Uo5]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATFQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLSDRYQSVSEMYVDLSTSLSYNRRNEPKLVFDDASKADTKTLPKVPQSTLTSIPKAPAQEERPQPK
KPTQPVAEPAPSPKPAKKRKFKARYMILLASLLLVVASLVWILSRTPATIPIPDVAGQTVAEAKEALKKSKFEAGEEKSE
ASDTVAEGRVIRTDPEAGSGRKEGTKVNLIVSSGKQSFQLSNYVGRKYTDVVAELKEKKVPENLIKMEEEESSESEPGTV
LRQTPASGSTYDLSKATTITLTVAKKVTSVSMPNYIGSSLEFTKNNLTQIVGVKEANIEVVEVSTAPEGTAEGTVVSQTP
RAGELVDLASTRIKLSIYKPKTPPSTSSSNPAQRGNQGSPTSPNQGNQQGNQQGNTPSSSSSNSEGTHESSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=40209 SOR_RS07525 WP_000614524.1 1493922..1495823(-) (stkP) [Streptococcus oralis Uo5]
ATGATCCAAATCGGCAAGATTTTTGCCGGGCGGTATCGGATTGTCAAGCAGATTGGTCGAGGAGGCATGGCAGATGTTTA
CTTGGCCAAGGATTTGATCCTAGATGGGGAAGAAGTGGCAGTGAAGGTCCTGAGGACCAACTACCAGACAGACCCGATTG
CTGTGGCACGTTTCCAACGTGAAGCGAGAGCCATGGCGGATCTGGACCATCCTCATATCGTTCGGATAACAGATATTGGT
GAGGAAGACGGTCAACAGTACCTGGCTATGGAATACGTAGCAGGTCTTGACCTCAAGCGTTATATCAAAGAACACTATCC
TCTTTCAAACGAAGAAGCGGTTCGGATTATGGGACAAATCCTCTTGGCGATGCGCTTAGCCCATACTCGAGGAATCGTTC
ACCGGGATTTGAAACCTCAAAATATCCTCTTGACACCTGACGGCACAGCTAAGGTCACGGACTTTGGGATTGCAGTAGCC
TTTGCGGAGACCAGTCTGACCCAGACGAACTCAATGCTGGGTTCTGTTCATTATTTGTCACCTGAGCAAGCACGTGGTTC
TAAAGCGACCTTCCAGAGTGATATCTATGCAATGGGGATTATCTTCTATGAGATGCTAACGGGACATATCCCTTATGATG
GGGATAGTGCGGTTACGATTGCCCTCCAGCATTTCCAGAAGCCACTACCGTCCGTCATAGCTGAAAATCCATCTGTCCCT
CAGGCTTTAGAAAATGTTGTCATCAAGGCAACTGCTAAGAAGTTGTCAGACCGTTATCAGTCTGTTTCAGAAATGTATGT
GGACTTGTCAACTAGCTTGTCTTATAATCGTCGGAATGAACCGAAACTGGTCTTTGACGATGCGAGTAAGGCAGACACTA
AGACTTTACCTAAAGTTCCACAAAGTACACTGACATCGATTCCTAAAGCTCCGGCGCAAGAAGAACGCCCTCAGCCAAAG
AAACCAACTCAACCAGTCGCAGAGCCAGCTCCATCGCCAAAGCCAGCCAAGAAACGGAAGTTTAAGGCTCGCTATATGAT
TCTTTTGGCTAGCCTTCTATTGGTTGTAGCCTCTTTGGTCTGGATTTTGTCAAGAACACCAGCAACGATTCCTATTCCTG
ACGTAGCCGGACAAACCGTTGCAGAGGCTAAGGAAGCTCTTAAAAAATCCAAGTTTGAAGCCGGTGAAGAAAAGTCAGAG
GCCAGCGATACAGTAGCAGAAGGACGAGTTATTCGAACGGATCCAGAAGCTGGTAGCGGCCGAAAAGAAGGAACCAAGGT
CAATTTGATTGTTTCTTCTGGTAAGCAATCCTTCCAATTGAGCAATTACGTCGGACGCAAGTATACAGATGTCGTAGCCG
AACTCAAGGAGAAGAAGGTTCCTGAAAATCTAATCAAGATGGAAGAGGAAGAATCCAGCGAAAGCGAACCTGGAACCGTC
CTCAGACAGACCCCTGCTTCGGGTTCGACTTATGATCTCTCAAAAGCCACTACGATTACCTTAACAGTGGCTAAGAAGGT
GACTAGTGTCAGCATGCCGAACTACATTGGTTCAAGCCTCGAATTTACAAAGAATAACTTGACTCAGATTGTCGGTGTGA
AGGAAGCAAATATTGAGGTTGTTGAAGTATCGACTGCTCCTGAAGGAACGGCAGAAGGAACTGTTGTAAGTCAAACGCCA
AGAGCAGGAGAACTGGTTGATCTTGCAAGTACGCGTATCAAACTTTCCATCTACAAACCAAAAACACCACCGTCAACTTC
ATCCTCTAATCCTGCCCAACGTGGGAACCAGGGTTCTCCTACAAGTCCAAACCAGGGGAACCAACAAGGAAATCAACAAG
GGAACACTCCTTCTAGCAGTTCATCCAATAGTGAAGGAACTCACGAAAGTTCTCGAGATTAA

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-227)

PASTA domain (PASTA)

(372-432)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(510-579)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QEX3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

78.498

92.575

0.727
  stkP Streptococcus pneumoniae D39

78.157

92.575

0.724
  stkP Streptococcus pneumoniae R6

78.157

92.575

0.724
  stkP Streptococcus pneumoniae Rx1

77.986

92.575

0.722
  pknB Streptococcus mutans UA159

56.499

91.153

0.515
  stkP/pknB Streptococcus salivarius strain HSISS4

52.445

93.681

0.491

Multiple sequence alignment