Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GLO19_RS10925 Genome accession   NZ_CP046247
Coordinates   2281966..2283264 (+) Length   432 a.a.
NCBI ID   WP_341722089.1    Uniprot ID   -
Organism   Enterococcus faecalis strain RF_1_1_25_1     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2276966..2288264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GLO19_RS10920 (GLO19_11250) rlmH 2281086..2281565 (-) 480 WP_002355021.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GLO19_RS10925 (GLO19_11255) htrA 2281966..2283264 (+) 1299 WP_341722089.1 trypsin-like peptidase domain-containing protein Regulator
  GLO19_RS10930 (GLO19_11260) ytpR 2283311..2283931 (-) 621 WP_002361057.1 YtpR family tRNA-binding protein -
  GLO19_RS10935 (GLO19_11265) - 2284142..2284597 (-) 456 WP_002385249.1 universal stress protein -
  GLO19_RS10940 (GLO19_11270) - 2284745..2285059 (-) 315 WP_002355015.1 thioredoxin family protein -
  GLO19_RS10945 (GLO19_11275) pepA 2285071..2286147 (-) 1077 WP_002355013.1 glutamyl aminopeptidase -
  GLO19_RS10950 (GLO19_11280) - 2286454..2286795 (+) 342 WP_002355012.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 44799.89 Da        Isoelectric Point: 4.9968

>NTDB_id=401926 GLO19_RS10925 WP_341722089.1 2281966..2283264(+) (htrA) [Enterococcus faecalis strain RF_1_1_25_1]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEVKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=401926 GLO19_RS10925 WP_341722089.1 2281966..2283264(+) (htrA) [Enterococcus faecalis strain RF_1_1_25_1]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTGTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCGATTG
GTTCCCCTCTAGGCTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAGTGAAAGCAACTATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(132-277)

PDZ domain (PDZ_2)

(319-416)

Peptidase family M50 (Peptidase_M50)

(9-417)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

53.171

94.907

0.505
  htrA Streptococcus mutans UA159

57.838

85.648

0.495
  htrA Streptococcus mitis NCTC 12261

55.135

85.648

0.472
  htrA Streptococcus pneumoniae TIGR4

55.807

81.713

0.456
  htrA Streptococcus pneumoniae Rx1

55.807

81.713

0.456
  htrA Streptococcus pneumoniae D39

55.807

81.713

0.456
  htrA Streptococcus pneumoniae R6

55.807

81.713

0.456

Multiple sequence alignment