Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SOR_RS03750 Genome accession   NC_015291
Coordinates   743082..743822 (+) Length   246 a.a.
NCBI ID   WP_000782701.1    Uniprot ID   F2QCR0
Organism   Streptococcus oralis Uo5     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 738082..748822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS03735 (SOR_0763) - 740200..740910 (+) 711 WP_000942449.1 LicD family protein -
  SOR_RS03740 (SOR_0764) - 741091..741435 (+) 345 Protein_696 N-acetylmuramoyl-L-alanine amidase family protein -
  SOR_RS03745 (SOR_0765) - 741481..742959 (-) 1479 WP_000789712.1 oligosaccharide flippase family protein -
  SOR_RS03750 (SOR_0766) mecA 743082..743822 (+) 741 WP_000782701.1 adaptor protein MecA Regulator
  SOR_RS03755 (SOR_0767) - 743970..745256 (+) 1287 WP_000216341.1 homoserine dehydrogenase -
  SOR_RS03760 (SOR_0768) thrB 745258..746127 (+) 870 WP_000692415.1 homoserine kinase -
  SOR_RS03765 (SOR_0769) msrB 746228..747166 (+) 939 WP_041170845.1 peptide-methionine (R)-S-oxide reductase MsrB -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28550.31 Da        Isoelectric Point: 4.1095

>NTDB_id=40192 SOR_RS03750 WP_000782701.1 743082..743822(+) (mecA) [Streptococcus oralis Uo5]
MKMKQISDTTLKITMTLDDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDNFLDSGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFEDLADLPDMEELAQMSPDEFLKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQADKETENKKEPYIYYILSFA
KLADLVSFAKTVNYQMETSELYKMNGHYYLTILVDVENHPSPYPAWLLARMREFADDSDISRSVLQEYGQILINHDAVLN
LQKIHS

Nucleotide


Download         Length: 741 bp        

>NTDB_id=40192 SOR_RS03750 WP_000782701.1 743082..743822(+) (mecA) [Streptococcus oralis Uo5]
ATGAAGATGAAACAAATTAGTGATACAACACTGAAAATCACGATGACTTTAGATGATTTGATGGATCGGGGAATGGAGAT
TGCAGACTTTCTCGTTCCTCAGGAAAAAACCGAAGAGTTTTTCTATGCTATTTTAGATGAGTTAGAGATGCCAGACAATT
TCTTGGATAGTGGCATGCTGAGTTTCCGCGTGACGCCAAAACCTGATAAGGTCGACGTCTTTGTGACCAAGTCCAAGATT
GACCAAAATTTGGATTTTGAAGATTTGGCGGATCTACCAGACATGGAAGAATTAGCCCAAATGTCGCCGGATGAATTTCT
CAAAACCTTGGAAAAGAGCATTGCAGATAAAACCAAGGACGATATTGAGGCCATCCAATCTCTAGAGCAGGTCGAAGCAA
AGGAAGAAGAGCAAGAGCAGGCAGACAAGGAGACTGAGAATAAGAAAGAACCTTACATCTACTACATCCTTTCTTTTGCG
AAGTTAGCTGACTTGGTTTCTTTTGCAAAGACGGTTAACTACCAGATGGAAACATCTGAACTCTATAAGATGAATGGACA
CTACTATTTGACAATCTTAGTCGATGTGGAAAATCATCCAAGTCCATATCCGGCTTGGCTCTTGGCTCGTATGCGTGAAT
TTGCAGATGATAGTGACATCAGTCGTTCAGTTTTGCAAGAGTATGGGCAAATCTTGATCAATCACGATGCAGTTCTTAAT
TTGCAAAAGATTCATTCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2QCR0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

91.393

99.187

0.906
  mecA Streptococcus pneumoniae D39

91.393

99.187

0.906
  mecA Streptococcus pneumoniae R6

91.393

99.187

0.906
  mecA Streptococcus pneumoniae TIGR4

90.984

99.187

0.902
  mecA Streptococcus thermophilus LMD-9

48.193

100

0.488
  mecA Streptococcus thermophilus LMG 18311

47.791

100

0.484
  mecA Streptococcus mutans UA159

48.361

99.187

0.48

Multiple sequence alignment