Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GLW17_RS05735 Genome accession   NZ_CP046246
Coordinates   1231790..1233058 (+) Length   422 a.a.
NCBI ID   WP_061840691.1    Uniprot ID   A0A2H6CVH6
Organism   Tetragenococcus halophilus strain YJ1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1226790..1238058
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GLW17_RS05710 (GLW17_05710) - 1227123..1228484 (-) 1362 WP_123985509.1 transposase -
  GLW17_RS05715 (GLW17_05715) - 1228753..1229232 (-) 480 WP_103083696.1 C-GCAxxG-C-C family protein -
  GLW17_RS05720 (GLW17_05720) msrA 1229327..1230157 (-) 831 WP_155224467.1 peptide-methionine (S)-S-oxide reductase MsrA -
  GLW17_RS05725 (GLW17_05725) - 1230398..1230925 (-) 528 WP_155224468.1 AAA family ATPase -
  GLW17_RS05730 (GLW17_05730) rlmH 1230969..1231448 (-) 480 WP_155224469.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GLW17_RS05735 (GLW17_05735) htrA 1231790..1233058 (+) 1269 WP_061840691.1 S1C family serine protease Regulator
  GLW17_RS05740 (GLW17_05740) ytpR 1233102..1233713 (-) 612 WP_014123649.1 YtpR family tRNA-binding protein -
  GLW17_RS05745 (GLW17_05745) - 1233766..1234224 (-) 459 WP_014123648.1 universal stress protein -
  GLW17_RS05750 (GLW17_05750) - 1234247..1234561 (-) 315 WP_014123647.1 thioredoxin family protein -
  GLW17_RS05755 (GLW17_05755) pepA 1234649..1235725 (-) 1077 WP_014123646.1 glutamyl aminopeptidase -
  GLW17_RS05760 (GLW17_05760) - 1235869..1236021 (+) 153 Protein_1156 aminoglycoside 6-adenylyltransferase -
  GLW17_RS05765 (GLW17_05765) - 1236113..1236454 (+) 342 WP_061840694.1 hypothetical protein -
  GLW17_RS05770 (GLW17_05770) pepV 1236566..1237978 (-) 1413 WP_155224470.1 dipeptidase PepV -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 43973.74 Da        Isoelectric Point: 3.7200

>NTDB_id=401881 GLW17_RS05735 WP_061840691.1 1231790..1233058(+) (htrA) [Tetragenococcus halophilus strain YJ1]
MAKKNVTPDSKKGGWIKKFGIGLLGGLIGGLLVIGGFYYFSNGNPFQTNEATSSSGVTDNNDDVQVSDVKVDADSDTTDA
VENVQNAVVSVINLQNSSPQESGGIFGTEQPEGNSEDDEEPAGEGSGVIYKEDGGDAYIVTNNHVVAGQSGLEVVMADGS
REQAELVGTDAYTDLAVLKISSDNVDTVATFGDSDELQVGEPAIAIGSPLGSDYANSVTQGIISSVNRLVSSQNESGEDV
STNAIQTDAAINPGNSGGPLVNAGGQVVGINSSKIASSGQAGVSVEGMGFAIPSNDVTDIINELEENGEIARPALGISML
DLNTIPTEQRQRVLQIPEDVENGVVVENPGDGTPASDAGLEQYDVITKVDDKEIKDSTELRAALYEKSVGDTLKLTFYRQ
DDAQSVNVKLSEDQSIIESNNE

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=401881 GLW17_RS05735 WP_061840691.1 1231790..1233058(+) (htrA) [Tetragenococcus halophilus strain YJ1]
ATGGCAAAAAAGAATGTAACACCTGATTCTAAAAAAGGCGGGTGGATTAAAAAATTCGGAATTGGCCTATTAGGTGGATT
AATAGGCGGGTTACTTGTCATTGGCGGCTTTTATTATTTTTCTAATGGTAACCCATTTCAAACAAATGAAGCAACTTCTT
CATCTGGCGTAACAGATAATAACGACGACGTACAGGTCAGTGATGTTAAAGTTGATGCCGATAGTGATACCACAGACGCT
GTAGAAAATGTACAAAATGCTGTCGTTTCAGTGATCAATTTACAAAACTCTTCTCCTCAAGAAAGCGGAGGTATTTTTGG
CACCGAGCAACCAGAAGGCAACTCTGAAGACGACGAGGAGCCAGCTGGTGAAGGTAGTGGTGTGATTTACAAAGAAGATG
GCGGCGATGCCTACATTGTAACAAATAATCACGTAGTTGCCGGACAAAGTGGCTTAGAAGTAGTTATGGCAGACGGTAGT
AGAGAACAAGCAGAATTAGTAGGTACTGATGCTTATACTGACTTAGCCGTATTAAAAATTTCTTCTGATAATGTAGACAC
AGTAGCTACATTCGGTGATTCTGATGAATTACAAGTAGGTGAACCAGCGATCGCTATTGGTTCTCCTCTAGGTTCTGATT
ATGCTAATTCAGTAACCCAAGGAATTATTTCTTCAGTCAATCGTTTAGTATCCAGCCAAAATGAATCTGGCGAAGATGTG
AGCACAAATGCTATTCAAACGGACGCTGCAATCAACCCAGGAAATTCTGGCGGGCCATTGGTCAATGCTGGTGGACAAGT
TGTTGGAATTAACTCCAGTAAAATTGCTAGTTCCGGACAAGCTGGCGTAAGTGTTGAAGGCATGGGCTTTGCTATTCCAA
GTAATGATGTAACAGATATTATTAATGAATTGGAAGAAAATGGTGAAATTGCTCGTCCAGCGTTAGGCATCTCCATGCTT
GATTTAAATACCATTCCTACAGAACAAAGACAACGTGTTTTACAAATCCCTGAGGATGTAGAAAACGGCGTTGTTGTAGA
AAACCCTGGCGATGGCACACCAGCAAGTGATGCAGGATTAGAACAATATGATGTTATTACAAAAGTTGACGATAAAGAAA
TAAAAGATTCTACTGAGCTACGTGCCGCTTTATATGAAAAATCAGTAGGAGATACTTTGAAATTGACTTTTTATCGACAA
GATGACGCACAATCTGTAAATGTTAAACTATCAGAAGATCAATCAATCATTGAAAGCAACAACGAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(313-410)

Trypsin-like peptidase domain (Trypsin_2)

(125-270)

Peptidase family M50 (Peptidase_M50)

(317-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2H6CVH6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

58.38

84.834

0.495
  htrA Streptococcus mitis NCTC 12261

50.256

92.417

0.464
  htrA Streptococcus gordonii str. Challis substr. CH1

49.745

92.891

0.462
  htrA Streptococcus pneumoniae TIGR4

49.744

92.417

0.46
  htrA Streptococcus pneumoniae D39

49.744

92.417

0.46
  htrA Streptococcus pneumoniae Rx1

49.744

92.417

0.46
  htrA Streptococcus pneumoniae R6

49.744

92.417

0.46

Multiple sequence alignment