Detailed information NTG0401489

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: GKC13_RS00015
• Genome accession: NZ_CP046134
• Coordinates: 2584..3819 (-)
• Length: 411 a.a.
• NCBI ID: WP_014608809.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MAG_rmk202_sterm
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1..8819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GKC13_RS00005 (GKC13_00005)	dnaA	147..1511 (-)	1365	WP_002948584.1	chromosomal replication initiator protein DnaA	-
GKC13_RS00010 (GKC13_00010)	spo0J	1751..2518 (-)	768	WP_002952299.1	ParB/RepB/Spo0J family partition protein	Regulator
GKC13_RS00015 (GKC13_00015)	htrA	2584..3819 (-)	1236	WP_014608809.1	trypsin-like peptidase domain-containing protein	Regulator
GKC13_RS00020 (GKC13_00020)	rlmH	4025..4504 (+)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
GKC13_RS00025 (GKC13_00025)	-	4520..5203 (+)	684	WP_011226711.1	YoaK family protein	-
GKC13_RS00045 (GKC13_00045)	-	5748..8354 (-)	2607	WP_041827400.1	YfhO family protein	-

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42915.25 Da
• Isoelectric Point: 4.7061

>NTDB_id=401489 GKC13_RS00015 WP_014608809.1 2584..3819(-) (htrA) [Streptococcus thermophilus strain MAG_rmk202_sterm]
MKKFNWKKIVVPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTVKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=401489 GKC13_RS00015 WP_014608809.1 2584..3819(-) (htrA) [Streptococcus thermophilus strain MAG_rmk202_sterm]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGTGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGTTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTCGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATTGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (6-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.097	100	0.601
htrA	Streptococcus gordonii str. Challis substr. CH1	57.389	98.783	0.567
htrA	Streptococcus mitis NCTC 12261	53.79	99.513	0.535
htrA	Streptococcus pneumoniae TIGR4	53.545	99.513	0.533
htrA	Streptococcus pneumoniae D39	53.545	99.513	0.533
htrA	Streptococcus pneumoniae Rx1	53.545	99.513	0.533
htrA	Streptococcus pneumoniae R6	53.545	99.513	0.533