Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GKQ55_RS11290 Genome accession   NZ_CP046112
Coordinates   2343463..2344761 (+) Length   432 a.a.
NCBI ID   WP_002415025.1    Uniprot ID   -
Organism   Enterococcus faecalis strain 111540027-2     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2338463..2349761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GKQ55_RS11285 (GKQ55_11670) rlmH 2342583..2343062 (-) 480 WP_002355021.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  GKQ55_RS11290 (GKQ55_11675) htrA 2343463..2344761 (+) 1299 WP_002415025.1 S1C family serine protease Regulator
  GKQ55_RS11295 (GKQ55_11680) ytpR 2344808..2345428 (-) 621 WP_002355018.1 YtpR family tRNA-binding protein -
  GKQ55_RS11300 (GKQ55_11685) - 2345639..2346094 (-) 456 WP_002385249.1 universal stress protein -
  GKQ55_RS11305 (GKQ55_11690) - 2346242..2346556 (-) 315 WP_002355015.1 thioredoxin family protein -
  GKQ55_RS11310 (GKQ55_11695) pepA 2346568..2347644 (-) 1077 WP_002355013.1 glutamyl aminopeptidase -
  GKQ55_RS11315 (GKQ55_11700) - 2347951..2348292 (+) 342 WP_002404031.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 44845.98 Da        Isoelectric Point: 4.9968

>NTDB_id=401080 GKQ55_RS11290 WP_002415025.1 2343463..2344761(+) (htrA) [Enterococcus faecalis strain 111540027-2]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSIINMQSASNNSSADDPFGGLFGGNEGTQDSSGNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=401080 GKQ55_RS11290 WP_002415025.1 2343463..2344761(+) (htrA) [Enterococcus faecalis strain 111540027-2]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCTCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTTTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTATCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCGGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCGATTG
GTTCCCCTCTAGGTTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCCGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGAATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGCGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACCATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(319-416)

Peptidase family M50 (Peptidase_M50)

(9-416)

Trypsin-like peptidase domain (Trypsin_2)

(132-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

52.927

94.907

0.502
  htrA Streptococcus mutans UA159

58.356

84.491

0.493
  htrA Streptococcus mitis NCTC 12261

54.865

85.648

0.47
  htrA Streptococcus pneumoniae TIGR4

55.524

81.713

0.454
  htrA Streptococcus pneumoniae Rx1

55.524

81.713

0.454
  htrA Streptococcus pneumoniae D39

55.524

81.713

0.454
  htrA Streptococcus pneumoniae R6

55.524

81.713

0.454

Multiple sequence alignment