Detailed information NTG0400901

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: HUK69_RS05725
• Genome accession: NZ_CP054788
• Coordinates: 1309270..1309941 (-)
• Length: 223 a.a.
• NCBI ID: WP_003090494.1
• Uniprot ID: A0A0H2ZC88
• Organism: Pseudomonas aeruginosa strain YTSY4
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1304270..1314941

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HUK69_RS05710 (HUK69_05715)	-	1305388..1307532 (+)	2145	WP_033943932.1	methyl-accepting chemotaxis protein	-
HUK69_RS05715 (HUK69_05720)	-	1307537..1307845 (-)	309	WP_003113384.1	hypothetical protein	-
HUK69_RS05720 (HUK69_05725)	carS	1307936..1309273 (-)	1338	WP_003090493.1	two-component system sensor histidine kinase CarS	-
HUK69_RS05725 (HUK69_05730)	ciaR	1309270..1309941 (-)	672	WP_003090494.1	two-component system response regulator CarR	Regulator
HUK69_RS05730 (HUK69_05735)	-	1309941..1310255 (-)	315	WP_003097704.1	PepSY domain-containing protein	-
HUK69_RS05735 (HUK69_05740)	-	1310255..1310563 (-)	309	WP_003090497.1	PepSY domain-containing protein	-
HUK69_RS05740 (HUK69_05745)	-	1310778..1311860 (+)	1083	WP_003113385.1	hypothetical protein	-
HUK69_RS05745 (HUK69_05750)	-	1311887..1312780 (+)	894	WP_003116712.1	hypothetical protein	-
HUK69_RS05750 (HUK69_05755)	-	1312764..1313030 (+)	267	WP_003115326.1	DUF5329 domain-containing protein	-
HUK69_RS05755 (HUK69_05760)	-	1313031..1314230 (-)	1200	WP_017001977.1	NnrS family protein	-
HUK69_RS05760 (HUK69_05765)	ppyR	1314217..1314474 (-)	258	WP_003090502.1	psl/pyoverdine operon transcriptional regulator PpyR	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 24729.20 Da
• Isoelectric Point: 5.8445

>NTDB_id=400901 HUK69_RS05725 WP_003090494.1 1309270..1309941(-) (ciaR) [Pseudomonas aeruginosa strain YTSY4]
MRLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLEILQEWRGLGLATPVLILTA
RGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRRAHGLANQSQLEAAGLRLDEQRQCVCLNGADVDLTAAEFRLLR
YFMLHPGQVLSKGHLAEHLYDGETERDSNVIEVHVNHLRRKLGREVIETRRGQGYRYAGVAAG

Nucleotide

• Length: 672 bp

>NTDB_id=400901 HUK69_RS05725 WP_003090494.1 1309270..1309941(-) (ciaR) [Pseudomonas aeruginosa strain YTSY4]
ATGCGGTTGCTGCTGGTTGAGGATCACGTTCCCCTGGCCGACGAACTGATGGCCAGCCTGACCCGCCAGGGCTACGCGGT
GGACTGGCTGGCCGACGGCCGCGACGCGGCGGTGCAGGGCGCCAGCGAGCCCTACGATCTGATCATCCTCGACCTCGGCC
TGCCCGGGCGTCCCGGCCTGGAGATACTCCAGGAGTGGCGTGGGCTGGGACTCGCGACTCCGGTGCTGATCCTCACCGCG
CGCGGTTCCTGGGCCGAACGCATCGATGGGCTCAAGGCCGGTGCCGACGACTACCTGACCAAGCCGTTCCATCCGGAAGA
GCTGGCCTTGCGCATCCAGGCCCTGTTGCGCCGCGCCCATGGGCTGGCCAACCAGAGCCAGCTGGAGGCCGCCGGGCTGC
GCCTGGACGAGCAGCGCCAGTGCGTGTGCCTGAACGGCGCCGACGTTGACCTGACCGCCGCCGAATTCCGCCTGCTGCGC
TATTTCATGCTGCACCCCGGCCAGGTCCTGTCCAAGGGGCACCTGGCCGAGCATCTGTACGACGGCGAGACCGAACGCGA
TTCCAACGTCATCGAGGTCCACGTCAACCACCTGCGGCGCAAGCTCGGCCGCGAGGTGATCGAGACCCGCCGTGGCCAGG
GCTACCGCTACGCCGGGGTGGCCGCCGGATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-216)

3D structure

• AlphaFold DB: A0A0H2ZC88

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	37.727	98.655	0.372
ciaR	Streptococcus pneumoniae Rx1	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae D39	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae R6	37.273	98.655	0.368
ciaR	Streptococcus pneumoniae TIGR4	37.273	98.655	0.368
micA	Streptococcus pneumoniae Cp1015	35.683	100	0.363
vicR	Streptococcus mutans UA159	35.526	100	0.363