Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   SGGBAA2069_RS10115 Genome accession   NC_015215
Coordinates   2027140..2029287 (+) Length   715 a.a.
NCBI ID   WP_013643495.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2022140..2034287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS10075 (SGGBAA2069_c19740) - 2022590..2023882 (-) 1293 WP_013643489.1 glycosyltransferase family 2 protein -
  SGGBAA2069_RS10080 (SGGBAA2069_c19750) - 2023884..2024183 (-) 300 WP_013643490.1 DUF3884 family protein -
  SGGBAA2069_RS10085 (SGGBAA2069_c19760) - 2024209..2024391 (-) 183 WP_013643491.1 hypothetical protein -
  SGGBAA2069_RS10090 (SGGBAA2069_c19770) - 2024473..2024682 (-) 210 WP_013643492.1 helix-turn-helix domain-containing protein -
  SGGBAA2069_RS10095 (SGGBAA2069_c19780) - 2024672..2025685 (-) 1014 WP_013643493.1 thiol reductase thioredoxin -
  SGGBAA2069_RS10100 (SGGBAA2069_c19790) - 2026062..2026259 (-) 198 WP_009855009.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  SGGBAA2069_RS10105 (SGGBAA2069_c19800) - 2026278..2026529 (-) 252 WP_009855010.1 bacteriocin class II family protein -
  SGGBAA2069_RS10110 (SGGBAA2069_c19820) - 2026776..2027033 (+) 258 WP_009855011.1 hypothetical protein -
  SGGBAA2069_RS10115 (SGGBAA2069_c19830) comA/nlmT 2027140..2029287 (+) 2148 WP_013643495.1 peptide cleavage/export ABC transporter Regulator
  SGGBAA2069_RS10120 (SGGBAA2069_c19840) - 2029299..2030693 (+) 1395 WP_013643496.1 bacteriocin secretion accessory protein -
  SGGBAA2069_RS10125 (SGGBAA2069_c19850) - 2030884..2031558 (+) 675 WP_012962518.1 CPBP family intramembrane glutamic endopeptidase -
  SGGBAA2069_RS12130 - 2031576..2031746 (+) 171 WP_012962519.1 hypothetical protein -
  SGGBAA2069_RS10130 (SGGBAA2069_c19860) - 2031764..2032435 (+) 672 WP_012962520.1 CPBP family intramembrane glutamic endopeptidase -
  SGGBAA2069_RS10135 (SGGBAA2069_c19870) rsmA 2032469..2033341 (-) 873 WP_012962521.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  SGGBAA2069_RS10140 (SGGBAA2069_c19880) - 2033411..2033935 (-) 525 WP_012962522.1 DUF1697 domain-containing protein -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 79904.63 Da        Isoelectric Point: 6.9233

>NTDB_id=40071 SGGBAA2069_RS10115 WP_013643495.1 2027140..2029287(+) (comA/nlmT) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MRRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKAIGFETRAIQANMELFDMADIPY
PFIVHVNKEGKLPHYYVIYKAKKDYLIIGDPDSSVGVTKMSKAHFAKEWTGVAIFLAPAPHYQPHKDKKNGLTSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNHLQSTLGIVSVGLIVTYIMQQIMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNANLFFITLIALPIYAIII
LAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEEVRYQNIDREFVDYLDKSFTLSKYEAVQTSLKQGAQLIL
NVVILWYGSHLVMAGNISVGQLITYNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDGKQLLNDSHFLQG
DIVFDDVSYKYGFGRDTLSHVNLHIKKGEKISLVGISGSGKTTLAKMIVNFYTPNHGQITLGGYDLKTIDKKAIRQYINY
LPQQSYVFSGTILENLTLGAPDNITQEEILKACEIAEIRADIESMPLAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDVLTEKRVIKNLLSLTDKTIIFVAHRLSIAEQSDRVIVLDKGQVIEEGYHKQLIQNQGFYAQLFHE

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=40071 SGGBAA2069_RS10115 WP_013643495.1 2027140..2029287(+) (comA/nlmT) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGAGAAGATATAAATATGTTAGTCAGATTGATTTGCGAGACTGTGGTGTGGCAGCTTTGGCATCAGTTGCCAAGCATTA
TGGATCAGATTTCTCGCTGGCTCATTTGAGAGAATTAGCCAAAACAACTAAGGAAGGGACAACAGCATTAGGGATAGTTG
AGGCAGCTAAAGCAATCGGCTTTGAAACACGCGCCATTCAGGCTAATATGGAACTGTTTGATATGGCTGATATTCCCTAT
CCTTTTATTGTTCATGTTAACAAAGAAGGCAAACTCCCGCATTACTATGTTATCTACAAAGCCAAAAAAGATTATCTTAT
TATCGGTGACCCTGATTCGAGCGTTGGGGTCACTAAAATGTCCAAAGCGCATTTTGCCAAAGAGTGGACTGGGGTTGCTA
TCTTTTTAGCGCCTGCTCCGCATTATCAACCACATAAAGATAAGAAAAATGGCTTAACAAGCTTTTTACCAATTATTTTC
AAACAAAAGGCACTGCTAACTTATATCATTCTGGCAAGTTTGCTCGTGACCTTGATTAATATTGTTGGGTCTTACTATTT
GCAAGGAATCTTAGACGATTATATTCCTAATCATTTGCAATCCACTCTTGGCATTGTCTCGGTTGGGTTGATTGTAACCT
ACATAATGCAACAAATCATGAGCTTTTCACAAAATTATTTACTTGTTGTGCTGAGCCAACGGTTAACAATTGACGTGATT
TTGTCTTATATTCGTCATATTTTTGAATTGCCCATGTCCTTTTTTGCCACAAGGCGGACAGGTGAAGTTATCTCACGTTT
CACCGATGCTAACTCGATTATTGATGCACTGGCATCAACGATTCTCTCTTTATTTTTAGATGTGAGTATTTTGTTTATTG
TCGGAAGTGTCTTAATTCTGCAAAATGCCAATCTTTTTTTCATCACCTTAATAGCATTGCCTATCTATGCTATTATTATT
TTGGCTTTTATGAAGCCTTTTGAGCGAATGAATCACGATGTCATGCAAGCCAATTCTATGGTTAGCTCTGCGATTATCGA
AGATATCAATGGTATTGAAACGATTAAATCTTTGACTAGCGAGGAAGTCCGTTATCAAAATATTGACCGTGAATTTGTGG
ATTATTTGGATAAAAGTTTTACGCTTAGTAAGTATGAAGCTGTGCAAACGTCGTTAAAACAGGGAGCACAGCTGATTTTA
AACGTCGTCATTCTCTGGTATGGTTCACATTTAGTCATGGCTGGGAACATTTCAGTAGGTCAATTGATTACTTACAATAC
GCTTCTGTCGTACTTTACAACACCAATGGAAAATATTATTAATCTGCAAACCAAACTACAATCTGCCAAAGTAGCTAACA
ATCGTCTCAACGAAGTTTACTTAGTGTCATCTGAATTTGATGGCAAACAACTCTTAAATGACAGCCATTTTCTACAAGGA
GATATTGTTTTTGATGATGTTTCTTATAAATATGGTTTTGGTCGTGACACACTGAGTCATGTGAATTTACACATTAAGAA
GGGTGAAAAAATTAGCCTAGTTGGTATCAGCGGTTCTGGTAAGACAACCTTAGCTAAAATGATTGTCAATTTTTACACAC
CTAACCATGGACAGATTACCCTTGGTGGCTACGATTTAAAAACCATTGATAAAAAAGCCATTCGCCAATACATTAATTAC
CTACCACAACAGTCTTACGTCTTTTCAGGGACGATTTTAGAAAATTTAACCTTGGGAGCACCTGACAATATCACGCAAGA
AGAAATTCTGAAAGCTTGTGAAATCGCTGAAATCCGTGCTGATATTGAATCGATGCCACTAGCATACCATACCGAACTTT
CAGATGGTGCTGGGTTATCTGGTGGGCAAAAGCAACGTTTAGCTTTAGCACGCGCTTTACTGACACAAGCTCCCGTCTTG
ATTTTAGATGAAGCCACAAGTGGTCTTGATGTTCTAACGGAAAAACGTGTGATTAAAAATTTACTATCTCTCACAGACAA
AACTATTATTTTTGTTGCCCACCGTTTGAGCATTGCTGAACAATCTGACCGTGTCATTGTTCTAGATAAAGGACAAGTTA
TCGAAGAAGGGTATCATAAACAACTCATCCAAAATCAAGGTTTCTATGCACAGTTATTTCATGAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-140)

ABC transporter (ABC_tran)

(498-647)

ABC transporter transmembrane region (ABC_membrane)

(166-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.126

99.72

0.699
  comA Streptococcus mitis NCTC 12261

66.901

99.301

0.664
  comA Streptococcus pneumoniae D39

66.384

99.021

0.657
  comA Streptococcus pneumoniae Rx1

66.384

99.021

0.657
  comA Streptococcus pneumoniae R6

66.384

99.021

0.657
  comA Streptococcus mitis SK321

66.197

99.301

0.657
  comA Streptococcus gordonii str. Challis substr. CH1

65.778

99.72

0.656
  comA Streptococcus pneumoniae TIGR4

66.102

99.021

0.655

Multiple sequence alignment