Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GJS33_RS08665 Genome accession   NZ_CP046041
Coordinates   1827301..1828065 (-) Length   254 a.a.
NCBI ID   WP_012677379.1    Uniprot ID   A0AAW3GKI0
Organism   Streptococcus equi subsp. zooepidemicus strain AZ-45470     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1822301..1833065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS33_RS08645 (GJS33_08645) - 1822639..1823865 (-) 1227 WP_014623468.1 cysteine desulfurase -
  GJS33_RS08650 (GJS33_08650) sufD 1823892..1825154 (-) 1263 WP_154299151.1 Fe-S cluster assembly protein SufD -
  GJS33_RS08655 (GJS33_08655) sufC 1825246..1826016 (-) 771 WP_012516290.1 Fe-S cluster assembly ATPase SufC -
  GJS33_RS08660 (GJS33_08660) - 1826137..1827294 (-) 1158 WP_041785937.1 glycosyltransferase family 4 protein -
  GJS33_RS08665 (GJS33_08665) mecA 1827301..1828065 (-) 765 WP_012677379.1 adaptor protein MecA Regulator
  GJS33_RS08670 (GJS33_08670) - 1828185..1829024 (-) 840 WP_014623473.1 undecaprenyl-diphosphate phosphatase -
  GJS33_RS08675 (GJS33_08675) - 1829340..1830908 (+) 1569 WP_154299152.1 ABC transporter substrate-binding protein/permease -
  GJS33_RS08680 (GJS33_08680) - 1830901..1831641 (+) 741 WP_014623475.1 amino acid ABC transporter ATP-binding protein -
  GJS33_RS08685 (GJS33_08685) - 1831988..1832104 (+) 117 WP_012677375.1 putative metal homeostasis protein -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29250.07 Da        Isoelectric Point: 4.2228

>NTDB_id=400549 GJS33_RS08665 WP_012677379.1 1827301..1828065(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHASPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=400549 GJS33_RS08665 WP_012677379.1 1827301..1828065(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGGGGGATGGAGCT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTCATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACTCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAATCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCTCAAATGACTCCAGAGGATTTTTTCAGAAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTCAATGCCCATGAAAAGCTTGAAAAAATCGAGGAGATCATGGAGGACGTGG
TTGATGCTACCTTGGCTGAGCAAGCAGATAGTAAGGAAGCTGCTGAGCTTGATGAGCCGACAGAGCCACTTGATTATGTT
CACTATGTTCTTGATTTTGCTTCTGTTCGAGACGCTGTTTGCTTTGCTAAGGTGATTGATTTTCCGATCGAGGCTTCTGA
ATTGTATAAGGGTCCTCGTCATTATCACATGACGATTTTACTTGATGTGCAAAACAAGCCTGCCTACTTTGCCAATGTGA
TGTATGCCAGATTGATTGAGCATGCTAGTCCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTACAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.745

98.819

0.63
  mecA Streptococcus thermophilus LMD-9

57.255

100

0.575
  mecA Streptococcus thermophilus LMG 18311

56.471

100

0.567
  mecA Streptococcus pneumoniae TIGR4

48.031

100

0.48
  mecA Streptococcus pneumoniae Rx1

47.638

100

0.476
  mecA Streptococcus pneumoniae D39

47.638

100

0.476
  mecA Streptococcus pneumoniae R6

47.638

100

0.476

Multiple sequence alignment