Detailed information NTG0400522

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: GJS33_RS04645
• Genome accession: NZ_CP046041
• Coordinates: 988275..988949 (+)
• Length: 224 a.a.
• NCBI ID: WP_021320708.1
• Uniprot ID: A0AAW3GMV5
• Organism: Streptococcus equi subsp. zooepidemicus strain AZ-45470
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 983275..993949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS33_RS04630 (GJS33_04630)	pstB	983602..984360 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
GJS33_RS04635 (GJS33_04635)	phoU	984431..985084 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
GJS33_RS04640 (GJS33_04640)	-	985319..987856 (+)	2538	WP_154298938.1	M1 family metallopeptidase	-
GJS33_RS04645 (GJS33_04645)	ciaR	988275..988949 (+)	675	WP_021320708.1	response regulator transcription factor	Regulator
GJS33_RS04650 (GJS33_04650)	ciaH	988942..990252 (+)	1311	WP_012515549.1	sensor histidine kinase	Regulator
GJS33_RS04655 (GJS33_04655)	-	990637..991071 (+)	435	WP_043026495.1	hypothetical protein	-
GJS33_RS09825	-	991153..991329 (+)	177	WP_014622814.1	hypothetical protein	-
GJS33_RS04660 (GJS33_04660)	-	991345..991752 (+)	408	WP_014622815.1	hypothetical protein	-
GJS33_RS04665 (GJS33_04665)	-	991762..992052 (+)	291	WP_126436648.1	hypothetical protein	-
GJS33_RS04670 (GJS33_04670)	-	991976..992359 (+)	384	WP_126436650.1	hypothetical protein	-
GJS33_RS04675 (GJS33_04675)	-	992361..992612 (+)	252	WP_043029681.1	hypothetical protein	-
GJS33_RS04680 (GJS33_04680)	-	992787..993167 (+)	381	WP_043029682.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25569.58 Da
• Isoelectric Point: 4.5644

>NTDB_id=400522 GJS33_RS04645 WP_021320708.1 988275..988949(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=400522 GJS33_RS04645 WP_021320708.1 988275..988949(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAATCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATTCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae Rx1	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae D39	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae R6	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae TIGR4	80.543	98.661	0.795
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.865	100	0.397