Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   GJS33_RS04650 Genome accession   NZ_CP046041
Coordinates   988942..990252 (+) Length   436 a.a.
NCBI ID   WP_012515549.1    Uniprot ID   A0AAW3GN95
Organism   Streptococcus equi subsp. zooepidemicus strain AZ-45470     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 983942..995252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS33_RS04635 (GJS33_04635) phoU 984431..985084 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  GJS33_RS04640 (GJS33_04640) - 985319..987856 (+) 2538 WP_154298938.1 M1 family metallopeptidase -
  GJS33_RS04645 (GJS33_04645) ciaR 988275..988949 (+) 675 WP_021320708.1 response regulator transcription factor Regulator
  GJS33_RS04650 (GJS33_04650) ciaH 988942..990252 (+) 1311 WP_012515549.1 sensor histidine kinase Regulator
  GJS33_RS04655 (GJS33_04655) - 990637..991071 (+) 435 WP_043026495.1 hypothetical protein -
  GJS33_RS09825 - 991153..991329 (+) 177 WP_014622814.1 hypothetical protein -
  GJS33_RS04660 (GJS33_04660) - 991345..991752 (+) 408 WP_014622815.1 hypothetical protein -
  GJS33_RS04665 (GJS33_04665) - 991762..992052 (+) 291 WP_126436648.1 hypothetical protein -
  GJS33_RS04670 (GJS33_04670) - 991976..992359 (+) 384 WP_126436650.1 hypothetical protein -
  GJS33_RS04675 (GJS33_04675) - 992361..992612 (+) 252 WP_043029681.1 hypothetical protein -
  GJS33_RS04680 (GJS33_04680) - 992787..993167 (+) 381 WP_043029682.1 hypothetical protein -
  GJS33_RS04685 (GJS33_04685) - 993164..994372 (+) 1209 WP_154298940.1 hypothetical protein -
  GJS33_RS04690 (GJS33_04690) - 994369..994761 (+) 393 WP_111692428.1 hypothetical protein -
  GJS33_RS04695 (GJS33_04695) - 994780..995058 (+) 279 WP_228269168.1 hypothetical protein -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49574.22 Da        Isoelectric Point: 9.6507

>NTDB_id=400523 GJS33_RS04650 WP_012515549.1 988942..990252(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=400523 GJS33_RS04650 WP_012515549.1 988942..990252(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGAATAAACTAAAAAAAGGATTATTGTCCGATAATTATACGCATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCTAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGATAAAAGCCAGCTCAATAACATTG
TCACCACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTTCACATCAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTCCAGCAGCTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTGGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACAACTAATCTGTTAAATTTAGCTAGACGCGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGATACTGTTTTTGAAAACTATCAATTGGTTGCAGAAGAATCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACAGATAAGGCCTTACTAAAGCAGCTGATGACCATTTTGTTTGATAACGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACTGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGACGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAAGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGCGCCATCTTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.376

100

0.514
  ciaH Streptococcus pneumoniae D39

51.376

100

0.514
  ciaH Streptococcus pneumoniae R6

51.376

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.376

100

0.514

Multiple sequence alignment