Detailed information    

insolico Bioinformatically predicted

Overview

Name   pknB   Type   Regulator
Locus tag   GJS32_RS08220 Genome accession   NZ_CP046040
Coordinates   1734554..1736449 (-) Length   631 a.a.
NCBI ID   WP_138119682.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain OH-71905     
Function   modulate the activity of ComDE; modulate the activity of VicKR (predicted from homology)   
Competence regulation

Genomic Context

Location: 1729554..1741449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS32_RS08200 (GJS32_08200) - 1730671..1731312 (-) 642 WP_021321066.1 response regulator -
  GJS32_RS08205 (GJS32_08205) - 1731305..1732309 (-) 1005 WP_012516143.1 sensor histidine kinase -
  GJS32_RS08210 (GJS32_08210) liaF 1732306..1732998 (-) 693 WP_012679994.1 cell wall-active antibiotics response protein LiaF -
  GJS32_RS08215 (GJS32_08215) - 1733200..1734459 (+) 1260 WP_014622390.1 ISL3-like element ISSeq1 family transposase -
  GJS32_RS08220 (GJS32_08220) pknB 1734554..1736449 (-) 1896 WP_138119682.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GJS32_RS08225 (GJS32_08225) - 1736446..1737186 (-) 741 WP_012516146.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  GJS32_RS08230 (GJS32_08230) rsmB 1737224..1738546 (-) 1323 WP_154293457.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  GJS32_RS08235 (GJS32_08235) fmt 1738536..1739471 (-) 936 WP_012677492.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 631 a.a.        Molecular weight: 68527.69 Da        Isoelectric Point: 6.6073

>NTDB_id=400478 GJS32_RS08220 WP_138119682.1 1734554..1736449(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVLRTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSGVVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSIIDENPNVP
QALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYNRSRERKVIFDDVESTKPLPKVTPAPITAPKVSAASQASGAADTR
PEQTSQMDTLQKPQKKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEAGLKVGKVH
QIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDYQDVMTSLTETYGVPKSKIKIERIVTNEYPE
NTVISQSPSAGEKFNPAGKSKITLSVAVGDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYTPSSSSPTGFVQVSSPSS
KAIVSGQTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSASNPSAGDTTDSSSHTELGQNDAVITP

Nucleotide


Download         Length: 1896 bp        

>NTDB_id=400478 GJS32_RS08220 WP_138119682.1 1734554..1736449(-) (pknB) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
ATGATTCAGATTGGCAAGCTATTTGCTGGTCGTTATCGCATTCTAAAATCTATAGGCCGCGGTGGTATGGCGGATGTTTA
TTTAGCAAACGATTTGATTCTGGATAATGAGGACGTTGCCATTAAGGTCTTGCGGACCAATTATCAAACAGATCAGGTTG
CTGTTGCGCGTTTTCAAAGAGAAGCGCGAGCCATGGCTGAATTAAATCACCCCAATATTGTTGCCATTCGGGATATAGGC
GAGGAAGACGGACAGCAATTTTTAGTAATGGAATATGTTGATGGCTCTGATTTGAAAAAATACATTCAGGATCATGCGCC
ATTATCTAACAATGAGGTGGTGAGAATCATGGAAGAGGTTCTTTCTGCCATGACTCTGGCCCACCAAAAAGGAATTGTTC
ACAGGGATTTAAAGCCTCAAAACATTCTTTTGACCAAATCAGGTGTTGTTAAGGTTACAGATTTTGGGATTGCCGTTGCC
TTTGCAGAGACCAGTCTAACCCAGACAAATTCTATGCTAGGAAGTGTGCATTACCTCTCACCTGAGCAAGCGCGTGGTTC
TAAAGCGACAATTCAAAGTGATATTTACGCGATGGGAATCATGCTCTTTGAAATGCTAACAGGGCATATTCCTTATGATG
GCGATAGCGCTGTGACGATTGCTCTGCAGCATTTTCAAAAGCCGCTGCCCTCTATCATTGATGAAAATCCTAATGTGCCT
CAAGCCTTGGAAAACGTTGTTATTCGGGCCACTGCCAAAAAGCTAAGTGACCGTTATCGCTCGACCTTTGAGATGAGCAG
GGATTTGATGACAGCCCTTAGCTATAACCGCAGTCGTGAGCGTAAGGTTATTTTTGATGATGTCGAAAGCACAAAGCCAT
TACCAAAGGTCACACCAGCCCCTATCACAGCACCTAAGGTGTCGGCTGCCAGTCAGGCATCTGGAGCAGCTGATACTAGA
CCTGAGCAGACTAGCCAGATGGACACCCTGCAAAAGCCTCAAAAAAAGAAAAAAAATGGGCGCTTTTTAGGAACGCTCTT
AAAAATCTTATTTTCCTTTTTCGTTGTCGGTGTGGCTCTTTTTGCTTATCTGGTCTTGACCAAGCCAACTACGGTTAAGG
TTCCTGATGTGACAGGCTCTAGTCTCAATGCTGCCAAGCAGGTCTTGGAGGAGGCAGGACTAAAGGTCGGTAAGGTCCAT
CAGATTGAAAGCGACACAGTCAGTGAGGATCAGGTGGTTAAGACAAATCCTCAAGCTGGCTCAGCTAAGCGAAAAGGCTC
CAGCGTTGACCTTTACCTTTCGATCGGAAATAAAGGCTTTGAGATGGAAAATTATAAGGGACAGGATTATCAGGATGTGA
TGACCAGTCTGACTGAGACCTACGGTGTACCAAAGTCAAAAATCAAGATTGAGCGTATCGTGACAAATGAATACCCTGAA
AACACCGTTATTAGCCAGTCACCAAGCGCGGGAGAAAAATTTAACCCAGCTGGTAAATCCAAGATTACGCTTAGTGTAGC
AGTGGGTGATACGGTCATCATGCCAATGGTAACTGAGTACAGCTATGCAGATGCGGTGAATACACTAACAGCCCTAGGAA
TTGACGCCGCAAGGATCAAGGCCTACACTCCAAGCTCAAGCTCTCCGACGGGCTTTGTTCAGGTGAGCTCCCCAAGCTCA
AAGGCGATTGTCAGTGGGCAGACACCGTATTATGGTACCCAGATTAGCCTTTCTGAAAAGGGTGATATTAGCCTCTACCT
CTACCCTGAGGAGACACGTGCATCAAGCAGCTCATCGAGCTCTGATACCTCAGCTTCTAATCCATCAGCTGGAGATACAA
CAGACTCAAGCAGTCATACCGAATTAGGTCAAAATGACGCTGTTATAACACCGTAA

Domains

Predicted by InterProScan.

Protein kinase domain (Pkinase)

(12-232)

PASTA domain (PASTA)

(372-434)

PASTA domain (PASTA)

(441-506)

PASTA domain (PASTA)

(512-588)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pknB Streptococcus mutans UA159

65.546

94.295

0.618
  stkP/pknB Streptococcus salivarius strain HSISS4

62.415

93.185

0.582
  stkP Streptococcus pneumoniae TIGR4

59.302

81.775

0.485
  stkP Streptococcus pneumoniae D39

58.915

81.775

0.482
  stkP Streptococcus pneumoniae R6

58.915

81.775

0.482
  stkP Streptococcus pneumoniae Rx1

58.721

81.775

0.48

Multiple sequence alignment