Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   GJS32_RS08075 Genome accession   NZ_CP046040
Coordinates   1704236..1706392 (+) Length   718 a.a.
NCBI ID   WP_014623340.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain OH-71905     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1699236..1711392
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJS32_RS08035 (GJS32_08035) - 1699645..1700226 (-) 582 WP_038674062.1 GNAT family N-acetyltransferase -
  GJS32_RS08040 (GJS32_08040) - 1700480..1700893 (-) 414 WP_014623333.1 hypothetical protein -
  GJS32_RS08045 (GJS32_08045) - 1701555..1701740 (-) 186 WP_080004985.1 bacteriocin BlpN -
  GJS32_RS08050 (GJS32_08050) - 1701764..1702018 (-) 255 WP_014623335.1 Blp family class II bacteriocin -
  GJS32_RS08055 (GJS32_08055) - 1702755..1703054 (-) 300 WP_014623336.1 bacteriocin immunity protein -
  GJS32_RS08060 (GJS32_08060) - 1703061..1703309 (-) 249 WP_014623337.1 garvicin Q family class II bacteriocin -
  GJS32_RS08065 (GJS32_08065) - 1703463..1703759 (-) 297 WP_014623338.1 bacteriocin immunity protein -
  GJS32_RS08070 (GJS32_08070) - 1703759..1703977 (-) 219 WP_038674059.1 leucocin A/sakacin P family class II bacteriocin -
  GJS32_RS08075 (GJS32_08075) comA/nlmT 1704236..1706392 (+) 2157 WP_014623340.1 peptide cleavage/export ABC transporter Regulator
  GJS32_RS08080 (GJS32_08080) - 1706403..1707761 (+) 1359 WP_038674057.1 bacteriocin secretion accessory protein -
  GJS32_RS08085 (GJS32_08085) - 1707861..1707995 (+) 135 WP_014623342.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  GJS32_RS10840 (GJS32_08090) - 1708114..1709448 (-) 1335 WP_038674055.1 sensor histidine kinase -
  GJS32_RS08095 (GJS32_08095) comE/blpR 1709448..1710197 (-) 750 WP_014623345.1 LytR/AlgR family response regulator transcription factor Regulator
  GJS32_RS08100 (GJS32_08100) - 1710831..1711025 (-) 195 WP_038674052.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  GJS32_RS08105 (GJS32_08105) - 1711042..1711299 (-) 258 WP_038674051.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80614.85 Da        Isoelectric Point: 8.0728

>NTDB_id=400475 GJS32_RS08075 WP_014623340.1 1704236..1706392(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
IIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLIIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYVFNGSILENLTLGAKQGISQEDILKACEIANIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=400475 GJS32_RS08075 WP_014623340.1 1704236..1706392(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain OH-71905]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCTTCGATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATGGGATTTGAAACCAGACCCATTCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGTCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAGCCCTTATTTTTTATATCGTGTTAGCTTCTGTCTTGGTAACAGTCATTAATATTGCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATTCCAGTATATACC
ATTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTAGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCACAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATCGGGCAGTTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACTAAGCTCCAAGCAGCTAAGG
TTGCCAACAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTATAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAT
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATGTGTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAGGGCAT
CAGCCAGGAAGACATTCTTAAAGCCTGTGAGATTGCTAACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTTGTTCTTAATCAAG
GGCAAATCATTGAGACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-439)

Peptidase C39 family (Peptidase_C39)

(8-143)

ABC transporter (ABC_tran)

(501-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

70.99

99.861

0.709
  comA Streptococcus mitis SK321

67.602

99.304

0.671
  comA Streptococcus mitis NCTC 12261

67.321

99.304

0.669
  comA Streptococcus pneumoniae D39

66.9

99.304

0.664
  comA Streptococcus pneumoniae Rx1

66.9

99.304

0.664
  comA Streptococcus pneumoniae R6

66.9

99.304

0.664
  comA Streptococcus pneumoniae TIGR4

66.62

99.304

0.662
  comA Streptococcus gordonii str. Challis substr. CH1

65.358

99.304

0.649

Multiple sequence alignment