Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SGGBAA2069_RS01755 Genome accession   NC_015215
Coordinates   324208..324963 (+) Length   251 a.a.
NCBI ID   WP_009853397.1    Uniprot ID   A0A060RH68
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 319208..329963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS01740 (SGGBAA2069_c03010) - 319617..321188 (-) 1572 WP_009853395.1 ABC transporter permease subunit -
  SGGBAA2069_RS01745 (SGGBAA2069_c03020) - 321321..323216 (+) 1896 WP_009853396.1 DUF2207 domain-containing protein -
  SGGBAA2069_RS01750 (SGGBAA2069_c03030) - 323268..324107 (+) 840 WP_013642683.1 undecaprenyl-diphosphate phosphatase -
  SGGBAA2069_RS01755 (SGGBAA2069_c03040) mecA 324208..324963 (+) 756 WP_009853397.1 adaptor protein MecA Regulator
  SGGBAA2069_RS01760 (SGGBAA2069_c03050) - 324965..326128 (+) 1164 WP_012961420.1 glycosyltransferase family 4 protein -
  SGGBAA2069_RS01765 (SGGBAA2069_c03060) sufC 326242..327012 (+) 771 WP_013642684.1 Fe-S cluster assembly ATPase SufC -
  SGGBAA2069_RS01770 (SGGBAA2069_c03070) sufD 327086..328348 (+) 1263 WP_012961421.1 Fe-S cluster assembly protein SufD -
  SGGBAA2069_RS01775 (SGGBAA2069_c03080) - 328350..329582 (+) 1233 WP_009853400.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 251 a.a.        Molecular weight: 28762.55 Da        Isoelectric Point: 4.0664

>NTDB_id=40031 SGGBAA2069_RS01755 WP_009853397.1 324208..324963(+) (mecA) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRIDVFVTKSEI
NKEINFEDLAAFDDVSNMSPEEFFKTLEQTMLSKGDTEAHEKLGKIEEMMEGAVEEVLTEQAQAEPTEEDINPSDYVHYV
LDFPTLEAVVAFAKAIDFPVEASELYKDGGLYHMTILLDLQNHPSYYANLMYARLLEYASAGTKTRAYLQEHGVEMLADD
AVAKLKMIELV

Nucleotide


Download         Length: 756 bp        

>NTDB_id=40031 SGGBAA2069_RS01755 WP_009853397.1 324208..324963(+) (mecA) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGGAAATGAAACAGATTAGCGAGACAACGCTAAAAATAACGATTAGTATGGAAGATTTAGAAGAACGTGGCATGGAGTT
GAAAGACTTTTTGATTCCACAAGAAAAGACAGAAGAGTTCTTCTACTCAGTAATGGACGAATTAGATTTACCAGATAATT
TCAAAGATAGTGGAATGCTTAGCTTTCGTGTGACACCAAGAAAAGACCGTATTGATGTCTTTGTTACAAAATCTGAAATC
AATAAAGAAATTAATTTCGAAGATTTAGCTGCATTCGACGACGTGTCAAACATGTCACCTGAGGAATTTTTCAAAACATT
GGAACAAACAATGCTTTCTAAAGGTGATACTGAGGCGCATGAAAAATTAGGAAAAATCGAAGAAATGATGGAAGGTGCTG
TTGAGGAAGTTCTCACAGAACAAGCTCAAGCAGAGCCAACAGAAGAGGATATTAATCCATCTGATTATGTTCATTATGTC
CTTGATTTTCCAACACTTGAAGCTGTCGTAGCTTTTGCTAAAGCAATTGATTTTCCAGTTGAAGCATCAGAACTCTACAA
AGATGGCGGTCTTTACCACATGACCATTTTACTTGATTTGCAAAATCATCCGTCTTACTATGCGAATTTGATGTATGCTC
GTTTGTTGGAATATGCTAGCGCAGGTACAAAAACGCGTGCTTATTTGCAAGAGCACGGTGTTGAAATGTTAGCAGATGAC
GCTGTTGCAAAATTAAAAATGATTGAGTTGGTATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060RH68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

67.742

98.805

0.669
  mecA Streptococcus thermophilus LMD-9

60.729

98.406

0.598
  mecA Streptococcus thermophilus LMG 18311

60.324

98.406

0.594
  mecA Streptococcus pneumoniae Rx1

48.617

100

0.49
  mecA Streptococcus pneumoniae D39

48.617

100

0.49
  mecA Streptococcus pneumoniae R6

48.617

100

0.49
  mecA Streptococcus pneumoniae TIGR4

48.617

100

0.49

Multiple sequence alignment