Detailed information NTG0399440

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: GJE16_RS09660
• Genome accession: NZ_CP045931
• Coordinates: 1885126..1885428 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain AUSMDU00010538
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1880126..1890428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJE16_RS09625 (GJE16_09625)	rnpA	1880806..1881177 (-)	372	WP_000739246.1	ribonuclease P protein component	-
GJE16_RS11270	-	1881194..1881325 (-)	132	WP_000768904.1	hypothetical protein	-
GJE16_RS09630 (GJE16_09630)	-	1881326..1882516 (-)	1191	WP_000167766.1	acetate kinase	-
GJE16_RS09635 (GJE16_09635)	comYH	1882567..1883520 (-)	954	WP_000345117.1	class I SAM-dependent methyltransferase	Machinery gene
GJE16_RS09645 (GJE16_09645)	-	1883581..1884174 (-)	594	Protein_1867	class I SAM-dependent methyltransferase	-
GJE16_RS09650 (GJE16_09650)	comGG/cglG	1884311..1884724 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
GJE16_RS09655 (GJE16_09655)	comGF/cglF	1884702..1885163 (-)	462	WP_000250530.1	competence type IV pilus minor pilin ComGF	Machinery gene
GJE16_RS09660 (GJE16_09660)	comGE/cglE	1885126..1885428 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
GJE16_RS09665 (GJE16_09665)	comGD/cglD	1885391..1885795 (-)	405	WP_000588006.1	competence type IV pilus minor pilin ComGD	Machinery gene
GJE16_RS09670 (GJE16_09670)	comGC/cglC	1885788..1886114 (-)	327	WP_000738638.1	comG operon protein ComGC	Machinery gene
GJE16_RS09675 (GJE16_09675)	comGB/cglB	1886116..1887132 (-)	1017	WP_075270915.1	competence type IV pilus assembly protein ComGB	Machinery gene
GJE16_RS09680 (GJE16_09680)	comGA/cglA/cilD	1887080..1888021 (-)	942	WP_000249556.1	competence type IV pilus ATPase ComGA	Machinery gene
GJE16_RS09685 (GJE16_09685)	-	1888096..1888461 (-)	366	WP_000286415.1	DUF1033 family protein	-
GJE16_RS09690 (GJE16_09690)	-	1888612..1889670 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=399440 GJE16_RS09660 WP_000413382.1 1885126..1885428(-) (comGE/cglE) [Streptococcus pneumoniae strain AUSMDU00010538]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=399440 GJE16_RS09660 WP_000413382.1 1885126..1885428(-) (comGE/cglE) [Streptococcus pneumoniae strain AUSMDU00010538]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4