Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   FOC73_RS04460 Genome accession   NZ_CP053998
Coordinates   950665..951408 (-) Length   247 a.a.
NCBI ID   WP_002885796.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_771     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 945665..956408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC73_RS04445 (FOC73_04445) rnpA 946389..946724 (-) 336 WP_002891957.1 ribonuclease P protein component -
  FOC73_RS04450 (FOC73_04450) argH 946809..948194 (-) 1386 WP_002885618.1 argininosuccinate lyase -
  FOC73_RS04455 (FOC73_04455) - 948521..949720 (-) 1200 WP_002885646.1 argininosuccinate synthase -
  FOC73_RS04460 (FOC73_04460) comE/blpR 950665..951408 (-) 744 WP_002885796.1 LytTR family DNA-binding domain-containing protein Regulator
  FOC73_RS04465 (FOC73_04465) - 951410..952726 (-) 1317 WP_002885807.1 GHKL domain-containing protein -
  FOC73_RS04470 (FOC73_04470) - 952750..954030 (-) 1281 WP_002885700.1 hypothetical protein -
  FOC73_RS04475 (FOC73_04475) - 954052..954942 (-) 891 WP_002885882.1 hypothetical protein -
  FOC73_RS04480 (FOC73_04480) - 955002..956309 (-) 1308 WP_002885760.1 GHKL domain-containing protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28536.83 Da        Isoelectric Point: 6.7589

>NTDB_id=396894 FOC73_RS04460 WP_002885796.1 950665..951408(-) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_771]
MNIYILEDDLMQQTRISDIIRELVSEGTFSVRKLEVFSKPHKLLSSINEKGNHQVFLLDIDIDGERKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIDKTVSNAEFKQQLKQTLTFVNQKVGDVDDDEIFVFETAQSRIQVPMRDIYY
FATAVTPHKVMLITKTERLEFYANLGDITSVNKKLFSCHRSFLVNLDNISRIDKTQLMIYFENGDSCPVSRLKMKALLKK
WSEVKEH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=396894 FOC73_RS04460 WP_002885796.1 950665..951408(-) (comE/blpR) [Streptococcus salivarius strain FDAARGOS_771]
ATGAATATATACATTTTAGAAGATGACTTAATGCAGCAAACACGTATTAGTGACATCATCAGAGAATTGGTTTCAGAGGG
CACGTTTTCCGTACGAAAACTTGAAGTTTTTTCTAAACCTCACAAACTATTGTCCAGTATCAATGAAAAGGGCAACCATC
AGGTTTTCCTTTTAGATATCGATATTGATGGTGAGCGAAAGAAGGGGCTAGAAGTTGCCTCAGAAATTCGTCAACAAGAT
GCTAATGCAGTTATTATTTTTGTAACAACTCACTCAGAGTTTGCACCGATTAGTTTTAAATACAAGGTTTCTGCACTAGA
TTTCATTGATAAGACAGTTTCTAATGCAGAGTTCAAACAACAACTAAAACAAACATTGACTTTTGTGAACCAAAAAGTTG
GAGATGTGGATGATGATGAGATTTTTGTGTTTGAAACCGCTCAGTCTCGGATCCAAGTCCCTATGAGAGATATTTATTAT
TTTGCGACTGCTGTGACACCTCATAAGGTGATGCTGATTACTAAAACAGAGCGTTTGGAGTTTTATGCCAATCTTGGAGA
TATTACTTCGGTAAATAAAAAACTCTTTTCTTGTCATCGCTCATTTTTAGTTAATTTGGATAACATATCTCGTATTGATA
AGACTCAGTTGATGATTTACTTTGAAAATGGTGATTCTTGTCCAGTTTCACGTTTGAAAATGAAGGCTCTGCTTAAAAAA
TGGTCAGAGGTAAAAGAACATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.5

97.166

0.462
  comE/comE2 Streptococcus equinus JB1

42.857

99.19

0.425
  comE/comE1 Streptococcus equinus JB1

40.496

97.976

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.402

100

0.385
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.402

100

0.385

Multiple sequence alignment