Detailed information NTG0396432

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: GH742_RS04865
• Genome accession: NZ_CP045732
• Coordinates: 1025695..1028445 (-)
• Length: 916 a.a.
• NCBI ID: WP_203456341.1
• Uniprot ID: -
• Organism: Legionella sp. MW5194
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1020695..1033445

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GH742_RS04830 (GH742_04810)	-	1021317..1021724 (+)	408	WP_203456335.1	hypothetical protein	-
GH742_RS04835 (GH742_04815)	-	1021726..1022169 (-)	444	WP_203456336.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
GH742_RS04840 (GH742_04820)	-	1022162..1022479 (-)	318	WP_203456337.1	BolA family transcriptional regulator	-
GH742_RS04845 (GH742_04825)	pilA2	1022800..1023210 (+)	411	WP_058525546.1	pilin	Machinery gene
GH742_RS04850 (GH742_04830)	pilA2	1023475..1023885 (+)	411	WP_203456338.1	pilin	Machinery gene
GH742_RS04855 (GH742_04835)	pilA2	1023997..1024407 (+)	411	WP_203456339.1	pilin	Machinery gene
GH742_RS04860 (GH742_04840)	-	1024436..1025671 (-)	1236	WP_203456340.1	6-phosphofructokinase	-
GH742_RS04865 (GH742_04845)	letS	1025695..1028445 (-)	2751	WP_203456341.1	two-component system sensor histidine kinase LetS	Regulator
GH742_RS04870 (GH742_04850)	gltX	1028596..1030014 (+)	1419	WP_203456342.1	glutamate--tRNA ligase	-
GH742_RS04875 (GH742_04855)	-	1030071..1030307 (+)	237	WP_203456343.1	hypothetical protein	-
GH742_RS04880 (GH742_04860)	-	1030347..1031798 (+)	1452	WP_203456344.1	YdiU family protein	-
GH742_RS04885 (GH742_04865)	-	1031804..1032835 (-)	1032	WP_203456345.1	hypothetical protein	-
GH742_RS04890 (GH742_04870)	-	1032999..1033421 (+)	423	WP_203456346.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 916 a.a.
• Molecular weight: 103007.99 Da
• Isoelectric Point: 6.3506

>NTDB_id=396432 GH742_RS04865 WP_203456341.1 1025695..1028445(-) (letS) [Legionella sp. MW5194]
MKELGIKYQLRLTTLIPVLLVALLFAVFFNGEFNKDLNQHMSRLGEAYIRQLLPAAQLAMMRNDRRVLQALVDASTVNPE
IIALAFYSADGQLIAYRGGKHLIKKPFKPLQYTGDYIESKQIEPYEINFLAPITIPKHNLYSASVFQSALERANLEPDDI
LGWLSIDIDTQSSVIKQYQMYIVTIFIILLGLLLSLSIHYFLSKRIYLPLARLRRSMKQILSNEFETHISVTSPGELGII
ERGCAHLQQQYLNTVRDLNHHIEVATEDLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKSSAQDLLTIINDILDYSKMDAGKLSLDCIPLDLRACVDEVLTLAAPNAHKKGIDLIPSTEV
NVPKTVLGDPIRIKQILTNLVTNAVKFTDRGYVLVKTCIEQETEKDYLFCLSVIDTGMGISSDDQTKLFNAFNQADTTIT
RRFGGSGLGLVICKKLAEEMKGRITLTSELHKGSTFAVRIRLEKLTAYESEKHQAHRFENIKAICYDDNPLHLEAMCNGL
VYCGIQCVPVASLSDLDKALATRDDCALAFVNVDEDSEEKIAGILRKYSKASILISKSIIHEPQRLGARGFLFRPISIQK
LHDTIETLINPSQPAPAAVNHELENLRGQLRLSHPDILIAEDNPVNRMLLHSFLNELANVETVNDGEEAVLASCEKHYQI
ILLDWQMPKLGGLDAAKRIRQQSSLNIATPIVVISADESTMSEEKLKKAGIDLYLQKPIEEKELLSALLSILRRSKPTAI
DWALCVQKVSGNQALAKEFLGRFVEELRENRKEFIQLYHDKNVKGLATAAHKLHGACCFCGVPNLQTQVTRLETHALKAK
HVNELETVFAQLIQSIDEVLDEFENIYQISSSNFGE

Nucleotide

• Length: 2751 bp

>NTDB_id=396432 GH742_RS04865 WP_203456341.1 1025695..1028445(-) (letS) [Legionella sp. MW5194]
ATGAAAGAACTCGGCATTAAATACCAACTGCGCCTCACGACCCTGATTCCAGTCCTGCTGGTCGCGTTGTTATTTGCGGT
GTTCTTCAACGGCGAATTCAATAAAGATTTAAACCAGCACATGTCCCGGCTTGGCGAAGCCTACATACGCCAATTGCTTC
CTGCCGCGCAGTTGGCCATGATGCGCAACGACCGCCGTGTCCTGCAGGCGCTGGTGGATGCCTCAACAGTCAATCCTGAA
ATCATTGCACTCGCGTTCTACAGCGCCGACGGCCAGCTCATTGCCTATCGCGGCGGCAAGCATCTGATTAAAAAACCCTT
TAAACCCCTGCAATACACTGGCGATTACATCGAAAGCAAACAGATTGAACCTTACGAAATTAATTTTTTAGCCCCGATTA
CCATCCCCAAACACAATCTATATTCTGCAAGCGTGTTTCAGTCGGCGCTGGAACGAGCCAATCTGGAGCCGGATGACATT
TTAGGCTGGCTGTCAATAGACATCGACACGCAATCGTCCGTGATTAAACAGTATCAAATGTACATCGTCACCATTTTTAT
CATCCTGTTGGGTTTGCTATTAAGCTTAAGCATTCATTATTTCCTTTCCAAACGCATTTACCTGCCCTTAGCCCGCCTGC
GCCGCAGCATGAAGCAGATTTTAAGTAATGAATTCGAAACCCATATTTCAGTCACCAGCCCTGGCGAACTGGGCATTATC
GAGCGCGGCTGCGCGCATTTACAGCAGCAATACCTCAACACAGTCAGAGACTTAAACCATCACATTGAAGTAGCCACCGA
AGATTTACAACAAAGCCTTGAATTGCTTGAAGAGAAAAACATCGAATTGTCCCTTGAAAAGAAAAAAACCGAAGAGAAAA
GTCGCCAGAAATCGGAATTCATTGCCAACATGAGCCATGAAATACGCACCCCCATGAACGGCGTTATCGGCTTCACCAAC
GTCCTTCTGGAAAGCAAGCTTGATCCTCTGCAGCTGGATTATGTCAAAACCATCAAGTCATCCGCCCAGGATTTGCTGAC
AATCATCAATGACATCCTCGATTACTCCAAAATGGATGCCGGGAAATTAAGCCTCGACTGCATCCCCCTTGATCTTCGTG
CCTGCGTCGATGAGGTATTGACCTTGGCCGCACCCAATGCCCATAAAAAAGGCATTGATTTGATTCCGTCCACGGAAGTG
AATGTACCGAAAACCGTGCTCGGCGATCCCATACGCATCAAGCAGATCCTGACGAACCTCGTTACCAATGCCGTTAAATT
CACCGACCGCGGTTATGTTCTGGTGAAAACCTGCATTGAACAGGAAACCGAAAAAGACTACCTGTTCTGTCTCTCCGTCA
TTGATACTGGCATGGGCATTTCCAGCGATGATCAGACCAAACTGTTCAATGCGTTTAATCAGGCGGATACCACGATCACC
CGCCGCTTTGGCGGTTCGGGCCTGGGACTTGTCATTTGCAAAAAACTCGCCGAAGAAATGAAAGGCCGTATTACCTTAAC
CAGTGAACTGCACAAAGGATCAACCTTCGCTGTGCGCATACGCCTTGAGAAATTAACCGCCTATGAAAGCGAGAAACACC
AGGCGCATCGGTTTGAGAACATCAAGGCCATCTGTTATGACGACAATCCCCTGCATCTGGAAGCCATGTGCAACGGCCTT
GTCTATTGCGGCATTCAATGCGTGCCGGTCGCGAGCCTTTCCGACCTGGACAAGGCGTTGGCTACACGGGATGATTGCGC
CCTTGCTTTTGTCAATGTCGATGAAGACTCTGAAGAGAAAATCGCGGGTATTCTGCGCAAGTACTCCAAAGCCTCCATTT
TAATTTCCAAATCCATTATTCATGAACCGCAACGACTCGGCGCCCGCGGCTTCCTGTTCAGACCCATCAGCATCCAGAAA
CTCCATGACACCATCGAAACCCTGATTAATCCGTCTCAACCTGCCCCTGCCGCAGTTAACCATGAGTTGGAGAATCTGCG
GGGGCAATTGCGGCTCTCCCATCCTGATATCCTGATTGCGGAAGACAATCCGGTTAACCGCATGCTGCTTCATTCCTTTC
TAAACGAACTCGCCAACGTTGAAACCGTGAACGATGGCGAAGAGGCGGTTTTGGCCTCTTGCGAAAAACATTACCAGATT
ATCCTGCTTGACTGGCAAATGCCAAAGCTTGGTGGATTAGACGCCGCCAAACGCATACGTCAGCAATCGTCGCTCAACAT
TGCCACCCCCATTGTGGTGATCAGTGCCGATGAGTCCACGATGAGCGAAGAGAAACTCAAAAAAGCCGGCATTGATCTGT
ACCTGCAAAAACCGATTGAGGAAAAGGAATTACTGTCAGCCCTGCTTTCCATTTTAAGACGCAGCAAACCAACGGCCATT
GATTGGGCGCTTTGTGTGCAGAAGGTATCCGGCAATCAGGCGCTGGCGAAAGAGTTTTTAGGTCGCTTTGTGGAAGAGCT
GCGCGAAAACCGCAAAGAATTTATTCAGTTATACCATGATAAAAACGTCAAGGGCTTAGCCACAGCGGCACACAAACTGC
ACGGCGCCTGCTGCTTTTGCGGGGTTCCCAATTTGCAGACCCAGGTAACCCGCCTGGAGACACATGCCTTAAAGGCCAAG
CATGTGAATGAACTGGAAACCGTTTTTGCCCAACTGATTCAAAGCATCGATGAAGTCCTCGATGAATTTGAAAACATTTA
CCAAATCAGTTCCTCGAATTTTGGCGAGTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-523)

• Single cache domain 4 (sCache_4) (35-179)

• Response regulator receiver domain (Response_reg) (677-788)

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

• Hpt domain (Hpt) (818-894)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	69.163	99.127	0.686