Detailed information NTG0394554

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: GE022_RS09365
• Genome accession: NZ_CP053790
• Coordinates: 1927112..1927852 (-)
• Length: 246 a.a.
• NCBI ID: WP_164405440.1
• Uniprot ID: -
• Organism: Streptococcus canis strain HL_77_2
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1922112..1932852

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE022_RS09330 (GE022_009320)	-	1922120..1922791 (-)	672	WP_172758335.1	DUF2786 domain-containing protein	-
GE022_RS09335 (GE022_009325)	-	1922781..1923059 (-)	279	WP_164405438.1	hypothetical protein	-
GE022_RS09340 (GE022_009330)	-	1923293..1923610 (-)	318	WP_223824838.1	DUF3021 domain-containing protein	-
GE022_RS10770	-	1923701..1923922 (-)	222	WP_223824837.1	LytTR family DNA-binding domain-containing protein	-
GE022_RS09350 (GE022_009340)	jag	1924498..1925406 (-)	909	WP_164405439.1	RNA-binding cell elongation regulator Jag/EloR	-
GE022_RS09355 (GE022_009345)	-	1925418..1926245 (-)	828	WP_275896970.1	YidC/Oxa1 family membrane protein insertase	-
GE022_RS09360 (GE022_009350)	rnpA	1926211..1926570 (-)	360	WP_093999455.1	ribonuclease P protein component	-
GE022_RS09365 (GE022_009355)	comE/blpR	1927112..1927852 (-)	741	WP_164405440.1	response regulator transcription factor	Regulator
GE022_RS09370 (GE022_009360)	-	1927856..1929139 (-)	1284	WP_164405441.1	sensor histidine kinase	-
GE022_RS09375 (GE022_009365)	-	1929140..1930483 (-)	1344	WP_164405442.1	GHKL domain-containing protein	-
GE022_RS09380 (GE022_009370)	gltX	1931105..1932553 (-)	1449	WP_159306074.1	glutamate--tRNA ligase	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28921.33 Da
• Isoelectric Point: 4.9564

>NTDB_id=394554 GE022_RS09365 WP_164405440.1 1927112..1927852(-) (comE/blpR) [Streptococcus canis strain HL_77_2]
MMNIFILEDDFIQQTRIESVVVAILEATKIPCNQLEVFSNPQKLFESIQERGDHQLYFLDIEIGDEARRGLELAVDIRQK
DPNAVIVFVTTHSEFVPISFKYKVSALDFIDKAADKEQFKEQIEDCIRYTYEMMSSRESEDIFLFETPQTRLKLPYKDIL
YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDRVVRIDKAKQLLYFENGDSCMVSRLKMKCLFE
KWESLH

Nucleotide

• Length: 741 bp

>NTDB_id=394554 GE022_RS09365 WP_164405440.1 1927112..1927852(-) (comE/blpR) [Streptococcus canis strain HL_77_2]
ATGATGAATATTTTTATTCTTGAAGATGATTTTATCCAGCAGACACGCATTGAGTCCGTGGTGGTGGCTATCTTGGAAGC
AACTAAAATCCCTTGTAATCAGCTAGAAGTATTTTCAAATCCCCAAAAATTATTTGAGAGCATTCAAGAAAGAGGAGACC
ATCAACTGTATTTTTTAGATATTGAGATTGGTGATGAGGCTCGTCGTGGGCTTGAGTTAGCAGTAGATATCCGCCAAAAA
GATCCCAATGCAGTGATTGTTTTTGTGACCACTCATTCTGAATTTGTACCTATTTCCTTCAAATATAAGGTTTCTGCTCT
GGATTTTATTGATAAGGCGGCAGATAAGGAGCAGTTCAAGGAACAAATTGAAGACTGTATTCGCTACACCTATGAGATGA
TGTCAAGTCGGGAATCTGAAGATATATTTTTGTTTGAAACGCCCCAGACCAGATTAAAGCTACCCTACAAAGATATTTTA
TACTTTGCCACAGCAACTACGCCCCACAAGGTGTGTTTGTGGACCCAGACGGAGAGACTGGAATTCTATGGTAATTTATC
TGAAATACAGGCCGTTGCTCCTAAGCTTTTCTTATGTCATAGGTCCTACTTGGTCAATCTTGATAGGGTTGTCCGCATTG
ACAAGGCCAAGCAGCTGCTTTATTTTGAAAATGGGGATTCCTGCATGGTTTCACGTTTGAAAATGAAATGCCTTTTTGAA
AAATGGGAGTCCCTTCATTAA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (152-242)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	48.117	97.154	0.467
comE/comE1	Streptococcus equinus JB1	42.437	96.748	0.411
comE/comE2	Streptococcus equinus JB1	40.408	99.593	0.402
comE/comE2	Streptococcus gordonii strain NCTC7865	38.525	99.187	0.382
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.525	99.187	0.382