Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   GE023_RS02735 Genome accession   NZ_CP053789
Coordinates   539363..541606 (+) Length   747 a.a.
NCBI ID   WP_159304869.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_98_2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 534363..546606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS02710 (GE023_002710) - 534486..536486 (+) 2001 WP_159304865.1 potassium transporter Kup -
  GE023_RS02715 (GE023_002715) - 536615..536893 (-) 279 WP_003044201.1 GIY-YIG nuclease family protein -
  GE023_RS02720 (GE023_002720) - 536883..537659 (-) 777 WP_302051297.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  GE023_RS02725 (GE023_002725) - 537777..538517 (+) 741 WP_003044195.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  GE023_RS02730 (GE023_002730) comEA 538720..539382 (+) 663 WP_159304868.1 ComEA family DNA-binding protein Machinery gene
  GE023_RS02735 (GE023_002735) comEC/celB 539363..541606 (+) 2244 WP_159304869.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GE023_RS02740 (GE023_002740) holA 541686..542726 (+) 1041 WP_003044192.1 DNA polymerase III subunit delta -
  GE023_RS02745 (GE023_002745) sodA 542823..543428 (+) 606 WP_003044189.1 superoxide dismutase SodA -
  GE023_RS02750 (GE023_002750) - 543594..544655 (+) 1062 WP_171004473.1 serine hydrolase -
  GE023_RS02755 (GE023_002755) - 544769..545989 (-) 1221 WP_159306017.1 DUF3114 domain-containing protein -

Sequence

Protein


Download         Length: 747 a.a.        Molecular weight: 85109.06 Da        Isoelectric Point: 9.7278

>NTDB_id=394396 GE023_RS02735 WP_159304869.1 539363..541606(+) (comEC/celB) [Streptococcus canis strain HL_98_2]
MTFSWTKLLPLPKIQLAFLVLVLFYHIYSPSWLTSLLSLGLICLLVKRLSKREFLSVFALLSLCALFLLYQKQQLTQELD
IQPVQITSVELIPDSIRINGDQLAVIGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVLHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQMEQLEVSSPKSVFDYLSSLRRQAIVHCQQHFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTYFRRLLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDAHFLMTVGGVLTFSYAFMLTIVTVEELSGAKRQLVQALIISLGMLPLLLFYFSSFNPMSIILTGLLSYLFDVLILPLL
CLVFCLSPLVTVSVCNHLFLLLEKGIQFLGNTVNTSLVFGSPTSWQLLLIVLSFAILYDYRQVRQRVFACGLVIALTLLS
VKYPLTNEVTIVDIGQGDSILIRDWRGKTLLIDVGGRPIFSKKEKWRSGYQTANAQKTLIPYLKSRGIHKIDQLLLTHTD
ADHMGDMEVVAKAIRVKEVLTSQGSLTNPSAVQRLNRLKCQVKVVKAGDQLSIMGSTLQVLYPWKLGDGKNNDSLVLYGK
LLNRTFLFTGDLEKEGEVEIIKRYPQLRVDYLKAGHHGSNTSSSAVFLDHLQPKLAFISAGKNNRYHHPSKETLTRLEDR
QITYYRTDTQGAIRLTGWTSWHLETVR

Nucleotide


Download         Length: 2244 bp        

>NTDB_id=394396 GE023_RS02735 WP_159304869.1 539363..541606(+) (comEC/celB) [Streptococcus canis strain HL_98_2]
ATGACATTTTCTTGGACTAAGCTATTGCCCCTGCCAAAGATTCAATTAGCTTTTTTGGTTTTGGTTCTCTTTTATCACAT
TTATAGTCCTAGCTGGTTAACTTCTCTTCTTAGTCTTGGTTTGATTTGCTTACTTGTAAAGCGTTTGTCTAAAAGAGAAT
TTCTCAGTGTTTTTGCCCTCCTTAGTTTATGTGCTTTGTTCTTACTCTATCAGAAACAACAGCTGACCCAAGAACTGGAC
ATTCAGCCAGTACAAATAACCTCTGTAGAATTGATTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTATTGG
ACGTCATGGGAAACACTCCTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAAAAAGAACACC
GTTGGTTAGTGCTGCACGCAAAAGTGACCTTGGAAAAAGCTGAGGAGGTTCGCAATTTTAAAGGATTTAATTACCAGACT
TTTTTGGCTTATCAGGGAATTTACAGGATAGGGAAGGTAGAGCAAATGGAACAGCTTGAAGTGAGCTCTCCAAAGTCAGT
GTTTGATTACTTGTCTTCCTTAAGACGGCAGGCCATTGTCCATTGTCAACAGCATTTTCCTAAACCCATGTCACACTACC
TGACAGGTCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGCCAGCTGGGCATCATTCAT
CTCTTTGCCTTATCAGGGATGCAGGTTGGTTTTTTTCTCACTTATTTTAGAAGGTTGTTGCTATTACTAGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGCTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGCATAAAAGGTTTAGACAATCTCGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGCCCATTTCTTAATGACTGTTGGTGGGGTATTAACATTTAGCTATGCTTTTATGTTAACAATAGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGCGCTAATTATCTCCCTAGGAATGTTACCGTTACTGCTGTTTTATT
TTTCCAGTTTTAATCCGATGTCAATAATATTAACAGGTCTCTTGTCTTACCTCTTTGACGTTTTGATTTTGCCTCTTCTT
TGTCTGGTTTTCTGTCTATCCCCTCTGGTGACTGTCTCAGTATGCAATCATCTCTTTCTTTTATTAGAAAAAGGGATTCA
ATTTCTTGGAAATACTGTCAATACTTCCCTTGTTTTTGGAAGTCCAACTAGTTGGCAATTACTTCTTATAGTGCTCAGCT
TTGCGATTCTTTATGACTATCGACAGGTGCGACAAAGGGTCTTCGCTTGTGGATTGGTCATAGCATTGACTTTACTGTCT
GTCAAATACCCTTTGACAAATGAAGTCACTATCGTTGATATTGGACAAGGAGATAGTATTTTGATAAGGGATTGGCGAGG
AAAGACACTCTTGATAGACGTTGGAGGACGTCCAATCTTTTCTAAAAAGGAGAAATGGCGCAGCGGTTATCAGACGGCGA
ATGCCCAAAAAACCTTAATCCCTTATTTAAAAAGCAGAGGCATTCATAAAATTGATCAGTTATTACTAACTCATACGGAT
GCTGATCACATGGGAGATATGGAAGTGGTTGCCAAAGCCATTCGAGTGAAGGAAGTGTTAACTAGCCAAGGTAGTTTAAC
GAACCCAAGTGCTGTGCAACGTTTAAACCGTTTAAAATGTCAGGTTAAGGTTGTTAAAGCTGGCGACCAGTTGTCCATTA
TGGGAAGCACCTTGCAGGTCCTCTATCCTTGGAAACTAGGAGATGGAAAAAATAATGATTCTTTGGTCCTCTATGGCAAG
CTATTAAATCGAACTTTTCTTTTCACAGGGGACTTGGAAAAAGAAGGAGAAGTTGAGATTATCAAACGTTATCCCCAGTT
AAGGGTGGATTATTTGAAAGCTGGCCATCATGGGTCAAATACTTCTTCAAGTGCAGTTTTTTTAGACCATCTTCAGCCCA
AGCTTGCTTTTATTTCTGCAGGAAAGAATAATCGGTACCACCATCCTAGTAAAGAGACCTTAACACGTTTGGAAGACAGA
CAAATCACGTATTATCGAACTGATACTCAAGGAGCTATTCGTTTGACTGGTTGGACCAGCTGGCATCTTGAAACGGTCCG
TTAG

Domains

Predicted by InterProScan.

Competence protein (Competence)

(217-462)

Metallo-beta-lactamase superfamily (Lactamase_B)

(495-696)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

47.059

100

0.471
  comEC/celB Streptococcus mitis NCTC 12261

46.917

99.866

0.469
  comEC/celB Streptococcus pneumoniae Rx1

45.455

100

0.455
  comEC/celB Streptococcus pneumoniae D39

45.455

100

0.455
  comEC/celB Streptococcus pneumoniae R6

45.455

100

0.455
  comEC/celB Streptococcus pneumoniae TIGR4

45.515

100

0.455
  comEC Lactococcus lactis subsp. cremoris KW2

42.013

99.732

0.419