Detailed information NTG0394375

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: GE023_RS00850
• Genome accession: NZ_CP053789
• Coordinates: 135924..136364 (+)
• Length: 146 a.a.
• NCBI ID: WP_003046192.1
• Uniprot ID: -
• Organism: Streptococcus canis strain HL_98_2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 130924..141364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE023_RS00820 (GE023_000820)	-	132598..132963 (+)	366	WP_125073632.1	DUF1033 family protein	-
GE023_RS00825 (GE023_000825)	comGA	133050..133991 (+)	942	WP_003046182.1	competence type IV pilus ATPase ComGA	Machinery gene
GE023_RS00830 (GE023_000830)	comGB	133924..134958 (+)	1035	WP_223824829.1	competence type IV pilus assembly protein ComGB	Machinery gene
GE023_RS00835 (GE023_000835)	comGC	134961..135287 (+)	327	WP_159305269.1	competence type IV pilus major pilin ComGC	Machinery gene
GE023_RS00840 (GE023_000840)	comGD	135262..135690 (+)	429	WP_236494085.1	competence type IV pilus minor pilin ComGD	Machinery gene
GE023_RS00845 (GE023_000845)	comGE	135668..135943 (+)	276	WP_003046190.1	competence type IV pilus minor pilin ComGE	Machinery gene
GE023_RS00850 (GE023_000850)	comGF	135924..136364 (+)	441	WP_003046192.1	competence type IV pilus minor pilin ComGF	Machinery gene
GE023_RS00855 (GE023_000855)	comGG	136342..136722 (+)	381	WP_003046193.1	competence type IV pilus minor pilin ComGG	-
GE023_RS00860 (GE023_000860)	comGH	136772..137725 (+)	954	WP_003046195.1	class I SAM-dependent methyltransferase	Machinery gene
GE023_RS00865 (GE023_000865)	-	137784..138980 (+)	1197	WP_093998734.1	acetate kinase	-
GE023_RS00870 (GE023_000870)	-	139300..139506 (+)	207	WP_003046200.1	helix-turn-helix transcriptional regulator	-
GE023_RS00875 (GE023_000875)	-	139507..139647 (+)	141	Protein_126	CPBP family glutamic-type intramembrane protease	-
GE023_RS10810	-	139772..139927 (+)	156	WP_236493542.1	hypothetical protein	-
GE023_RS00885 (GE023_000885)	proC	140233..141009 (-)	777	WP_159305271.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16879.42 Da
• Isoelectric Point: 10.5817

>NTDB_id=394375 GE023_RS00850 WP_003046192.1 135924..136364(+) (comGF) [Streptococcus canis strain HL_98_2]
MNKRTNRVRAFTFLEALIALLVISGSLLVYQGLTKTLLKHSHYLANHDQDHWLLFSQQLREELDGARFQKVTNNKLYIKK
GKKTLALGQSKSHDFRKSASNGQGYQPMLFGLSHTKIQADQSYVSIKLKWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=394375 GE023_RS00850 WP_003046192.1 135924..136364(+) (comGF) [Streptococcus canis strain HL_98_2]
TTGAACAAAAGGACAAATAGGGTTAGAGCGTTTACTTTTTTAGAAGCTTTAATTGCTCTGCTCGTTATATCAGGATCGCT
ATTAGTGTATCAAGGGCTAACTAAAACTCTCCTCAAGCACAGCCACTATCTGGCGAATCATGACCAAGATCATTGGCTTT
TGTTTTCCCAGCAGTTACGTGAAGAATTAGATGGAGCTAGGTTTCAAAAAGTAACAAATAACAAACTCTATATTAAAAAG
GGAAAGAAAACCTTAGCTTTAGGTCAATCTAAAAGCCATGATTTTCGGAAATCAGCTAGTAATGGTCAAGGTTACCAACC
CATGTTATTTGGTCTGTCTCATACTAAAATTCAGGCAGACCAGTCCTATGTTAGCATTAAGTTAAAATGGAAAAGTGGCT
TAGAAAGGACTTTTTATTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	49.286	95.89	0.473
comGF	Streptococcus mutans UA140	48.571	95.89	0.466
comGF	Lactococcus lactis subsp. cremoris KW2	45.652	94.521	0.432
comGF/cglF	Streptococcus pneumoniae TIGR4	45.255	93.836	0.425
comGF/cglF	Streptococcus pneumoniae R6	45.255	93.836	0.425
comGF/cglF	Streptococcus pneumoniae Rx1	45.255	93.836	0.425
comGF/cglF	Streptococcus pneumoniae D39	45.255	93.836	0.425
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411