Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   GBR75_RS02575 Genome accession   NZ_CP045468
Coordinates   551816..552385 (+) Length   189 a.a.
NCBI ID   WP_155560183.1    Uniprot ID   A0A6A9GZQ3
Organism   Staphylococcus aureus strain SAW1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 546816..557385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBR75_RS02550 (GBR75_02600) cysE 548029..548676 (+) 648 WP_117207899.1 serine O-acetyltransferase -
  GBR75_RS02555 (GBR75_02605) cysS 548660..550060 (+) 1401 WP_000631977.1 cysteine--tRNA ligase -
  GBR75_RS02560 (GBR75_02610) - 550053..550457 (+) 405 WP_000370186.1 Mini-ribonuclease 3 -
  GBR75_RS02565 (GBR75_02615) rlmB 550465..551211 (+) 747 WP_000390339.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  GBR75_RS02570 (GBR75_02620) - 551211..551735 (+) 525 WP_000664738.1 NYN domain-containing protein -
  GBR75_RS02575 (GBR75_02625) sigH 551816..552385 (+) 570 WP_155560183.1 sigma-70 family RNA polymerase sigma factor Regulator
  GBR75_RS02580 (GBR75_02630) rpmG 552500..552643 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  GBR75_RS02585 (GBR75_02635) secE 552699..552881 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  GBR75_RS02590 (GBR75_02640) nusG 552894..553442 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  GBR75_RS02595 (GBR75_02645) rplK 553623..554045 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  GBR75_RS02600 (GBR75_02650) rplA 554253..554945 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  GBR75_RS02610 (GBR75_02660) rplJ 555217..555717 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  GBR75_RS02615 (GBR75_02665) rplL 555760..556128 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  GBR75_RS02620 (GBR75_02670) - 556303..556911 (+) 609 WP_000020296.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23078.94 Da        Isoelectric Point: 9.6924

>NTDB_id=394373 GBR75_RS02575 WP_155560183.1 551816..552385(+) (sigH) [Staphylococcus aureus strain SAW1]
MKYNLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRIDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=394373 GBR75_RS02575 WP_155560183.1 551816..552385(+) (sigH) [Staphylococcus aureus strain SAW1]
TTGAAATATAATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAACAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATAGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAGCGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6A9GZQ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.413

100

0.984
  sigH Staphylococcus aureus N315

97.354

100

0.974

Multiple sequence alignment