Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HIBPF_RS01215 Genome accession   NC_014920
Coordinates   249423..250640 (-) Length   405 a.a.
NCBI ID   WP_013525532.1    Uniprot ID   A0AAV2U474
Organism   Haemophilus influenzae F3031     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 244423..255640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIBPF_RS01180 - 245596..245802 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  HIBPF_RS01185 (HIBPF02331) - 245888..246094 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  HIBPF_RS01190 (HIBPF02332) - 246169..246375 (-) 207 WP_013525530.1 heavy-metal-associated domain-containing protein -
  HIBPF_RS01195 (HIBPF02380) cueR 246452..246838 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  HIBPF_RS01200 (HIBPF02390) metJ 246852..247169 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  HIBPF_RS01205 (HIBPF02400) rho 247417..248679 (+) 1263 WP_005666690.1 transcription termination factor Rho -
  HIBPF_RS01210 (HIBPF02410) pilD 248734..249426 (-) 693 WP_013525531.1 prepilin peptidase Machinery gene
  HIBPF_RS01215 (HIBPF02420) pilC 249423..250640 (-) 1218 WP_013525532.1 type II secretion system F family protein Machinery gene
  HIBPF_RS01220 (HIBPF02430) pilB 250637..252031 (-) 1395 WP_013525533.1 GspE/PulE family protein Machinery gene
  HIBPF_RS01225 (HIBPF02431) pilA 252028..252477 (-) 450 WP_006996184.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  HIBPF_RS01230 (HIBPFp01) ampD 252592..253152 (+) 561 WP_006996183.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  HIBPF_RS01235 (HIBPF02460) corC 253775..254674 (+) 900 WP_013525534.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46062.22 Da        Isoelectric Point: 9.7233

>NTDB_id=39402 HIBPF_RS01215 WP_013525532.1 249423..250640(-) (pilC) [Haemophilus influenzae F3031]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=39402 HIBPF_RS01215 WP_013525532.1 249423..250640(-) (pilC) [Haemophilus influenzae F3031]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAATGAATGGCTTGAACGGCTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTCCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.537

100

0.978
  pilC Haemophilus influenzae Rd KW20

97.291

100

0.975
  pilC Glaesserella parasuis strain SC1401

38.5

98.765

0.38

Multiple sequence alignment