Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   HIBPF_RS01210 Genome accession   NC_014920
Coordinates   248734..249426 (-) Length   230 a.a.
NCBI ID   WP_013525531.1    Uniprot ID   A0AAV2U3Y4
Organism   Haemophilus influenzae F3031     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 243734..254426
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIBPF_RS01180 - 245596..245802 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  HIBPF_RS01185 (HIBPF02331) - 245888..246094 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  HIBPF_RS01190 (HIBPF02332) - 246169..246375 (-) 207 WP_013525530.1 heavy-metal-associated domain-containing protein -
  HIBPF_RS01195 (HIBPF02380) cueR 246452..246838 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  HIBPF_RS01200 (HIBPF02390) metJ 246852..247169 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  HIBPF_RS01205 (HIBPF02400) rho 247417..248679 (+) 1263 WP_005666690.1 transcription termination factor Rho -
  HIBPF_RS01210 (HIBPF02410) pilD 248734..249426 (-) 693 WP_013525531.1 prepilin peptidase Machinery gene
  HIBPF_RS01215 (HIBPF02420) pilC 249423..250640 (-) 1218 WP_013525532.1 type II secretion system F family protein Machinery gene
  HIBPF_RS01220 (HIBPF02430) pilB 250637..252031 (-) 1395 WP_013525533.1 GspE/PulE family protein Machinery gene
  HIBPF_RS01225 (HIBPF02431) pilA 252028..252477 (-) 450 WP_006996184.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  HIBPF_RS01230 (HIBPFp01) ampD 252592..253152 (+) 561 WP_006996183.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26800.82 Da        Isoelectric Point: 8.8532

>NTDB_id=39401 HIBPF_RS01210 WP_013525531.1 248734..249426(-) (pilD) [Haemophilus influenzae F3031]
MIYFTMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNFLPFQSSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWFGLTLLILWAISYLDWHYQLISTTLCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIQLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYWY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=39401 HIBPF_RS01210 WP_013525531.1 248734..249426(-) (pilD) [Haemophilus influenzae F3031]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTCGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTCCCACAAAACTTTCTGCCATTTCAGTCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGTTCGGACTCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACTACACTCTGTTTATGGTTACTTACAATCGGTTTATTTGGGGCAGACAATAACTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCAGTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATAATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

90.435

100

0.904
  pilD Haemophilus influenzae Rd KW20

90

100

0.9

Multiple sequence alignment