Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GCS73_RS13745 Genome accession   NZ_CP045308
Coordinates   3057516..3058175 (-) Length   219 a.a.
NCBI ID   WP_003635449.1    Uniprot ID   D3HKW5
Organism   Legionella longbeachae strain B41211CHC     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3052516..3063175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GCS73_RS13730 (GCS73_13630) - 3054013..3054579 (-) 567 WP_172622928.1 endopeptidase IV -
  GCS73_RS13735 (GCS73_13635) - 3054588..3055301 (-) 714 WP_003635452.1 L,D-transpeptidase -
  GCS73_RS13740 (GCS73_13640) uvrC 3055528..3057390 (-) 1863 WP_012979345.1 excinuclease ABC subunit UvrC -
  GCS73_RS13745 (GCS73_13645) letA 3057516..3058175 (-) 660 WP_003635449.1 two-component system response regulator LetA Regulator
  GCS73_RS13750 (GCS73_13650) phhA 3058284..3059102 (-) 819 WP_003635447.1 phenylalanine 4-monooxygenase -
  GCS73_RS13755 (GCS73_13655) - 3059384..3060226 (-) 843 WP_012979346.1 hypothetical protein -
  GCS73_RS13760 (GCS73_13660) - 3060258..3060584 (+) 327 WP_003635442.1 IS630 transposase-related protein -
  GCS73_RS13765 (GCS73_13665) - 3060613..3061083 (+) 471 WP_105166013.1 IS630 family transposase -
  GCS73_RS13770 (GCS73_13670) dinB 3061310..3062377 (-) 1068 WP_085956292.1 DNA polymerase IV -
  GCS73_RS13775 (GCS73_13675) - 3062570..3063076 (-) 507 WP_003635433.1 LexA family protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24346.37 Da        Isoelectric Point: 5.1733

>NTDB_id=393363 GCS73_RS13745 WP_003635449.1 3057516..3058175(-) (letA) [Legionella longbeachae strain B41211CHC]
MIKVLIVDDHALVRMGIRRLLEDMSDVEVVADAESGEQALVLVKQYSPDVVLLDMKMPGIDGWEVTRRLKKSNPHVKVIA
VTAMCSDVLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLEEAQGSPFNILSEREMQVMLMI
TSGMNVQEISDRLFLSTKTINGYRYRTFEKLGIKNDVELTYLALKHGIIENPTGLTSEE

Nucleotide


Download         Length: 660 bp        

>NTDB_id=393363 GCS73_RS13745 WP_003635449.1 3057516..3058175(-) (letA) [Legionella longbeachae strain B41211CHC]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTCGAATGGGTATTCGACGATTACTCGAAGATATGTCAGATGT
TGAAGTTGTTGCTGATGCAGAAAGTGGTGAACAAGCTTTAGTATTAGTAAAGCAATATTCCCCTGACGTAGTTCTTTTAG
ATATGAAAATGCCTGGGATAGATGGCTGGGAAGTAACCCGTCGTCTAAAAAAATCAAATCCACATGTTAAAGTCATAGCG
GTAACTGCAATGTGTTCTGATGTATTGCCCACCCGTGTTTTGCAATTAGGGGCTATGGGATATCTCACTAAAGAATCGGG
TGCTGAAGAAATGGCCGCTGCGATACGTAAGGTAGCTAAAGGGGAAAAATACCTTAGTGCTGAAATTGCTCAAAAAATGG
CAATCAACAGTTTGGAAGAAGCTCAAGGCTCACCTTTTAATATATTATCTGAACGAGAAATGCAGGTAATGTTGATGATT
ACCAGTGGCATGAATGTTCAGGAAATCAGCGATAGGCTTTTCTTGAGTACTAAAACAATCAATGGATATCGTTATCGTAC
GTTTGAGAAATTAGGTATAAAAAATGATGTTGAGCTGACCTACTTAGCTTTGAAACATGGAATCATAGAAAATCCTACTG
GTTTGACGTCAGAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3HKW5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

87.215

100

0.872
  letA Legionella pneumophila strain ERS1305867

87.215

100

0.872

Multiple sequence alignment