Detailed information NTG0393362

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: GCS73_RS13385
• Genome accession: NZ_CP045308
• Coordinates: 2971058..2973280 (+)
• Length: 740 a.a.
• NCBI ID: WP_003635596.1
• Uniprot ID: D3HKP4
• Organism: Legionella longbeachae strain B41211CHC
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2966058..2978280

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GCS73_RS13360 (GCS73_13260)	-	2966299..2966937 (-)	639	WP_003635606.1	hypothetical protein	-
GCS73_RS13365 (GCS73_13265)	-	2967179..2968204 (-)	1026	WP_003635604.1	ABC transporter substrate-binding protein	-
GCS73_RS13370 (GCS73_13270)	-	2968201..2968968 (-)	768	WP_003635601.1	ABC transporter permease subunit	-
GCS73_RS13375 (GCS73_13275)	-	2968965..2969789 (-)	825	WP_003635599.1	ABC transporter permease	-
GCS73_RS13380 (GCS73_13280)	potA	2969779..2970873 (-)	1095	WP_003635598.1	spermidine/putrescine ABC transporter ATP-binding protein PotA	-
GCS73_RS13385 (GCS73_13285)	comEC	2971058..2973280 (+)	2223	WP_003635596.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GCS73_RS13390 (GCS73_13290)	-	2973390..2974439 (+)	1050	WP_003635594.1	bifunctional transcriptional activator/DNA repair enzyme AdaA	-
GCS73_RS13395 (GCS73_13295)	-	2974796..2975023 (-)	228	WP_172622913.1	hypothetical protein	-
GCS73_RS13400 (GCS73_13300)	-	2975449..2976264 (-)	816	WP_003635585.1	mechanosensitive ion channel family protein	-
GCS73_RS13405 (GCS73_13305)	-	2976587..2976910 (-)	324	WP_003635583.1	hypothetical protein	-
GCS73_RS13410 (GCS73_13310)	-	2977245..2977631 (+)	387	WP_003635579.1	group III truncated hemoglobin	-
GCS73_RS13415	cydP	2977625..2977795 (+)	171	WP_003635577.1	cytochrome oxidase putative small subunit CydP	-

Sequence

Protein

• Length: 740 a.a.
• Molecular weight: 83609.84 Da
• Isoelectric Point: 9.6797

>NTDB_id=393362 GCS73_RS13385 WP_003635596.1 2971058..2973280(+) (comEC) [Legionella longbeachae strain B41211CHC]
MEIFCFFIGILYRYTLHGLLPILILFIFFIIPRYANILFFLLGIFIATVHQSQNLPKGLPDVEVIPQVSIQGTIASIPLQ
SPSKTLFLLALEQYDNHPAQGIIQLSWYNKAPKIHVGQRWKFKVKLKKPRNYLNPGSMDYVRSLATRHILWTGYIHSRGN
KQLPKVPSSFNWLELREQLSEQLGLLAPDQKTAGIVEALALNITTHIDQKSWDLFRRTGTTHLFGISGEHIALISGIIYW
LLRWIWTRSSRLCLRIPAPHIASMGGLLAASGYAFLAGFAPPVQRALIGCFFYTLYSLGYQRFTPWQVWRYALCGVLLIE
PHAVFMQGFYFSFLAVACLLLTQQRWRLKGYKASLALQLSCLIGLMPLTLYWYAYGSINGFIANLFAIPLVGLLIVPLSL
MTMTVSSLSIAKILMKAVSLLITLLFKGLSLSEYLAALNINCPIYSIELALVLIGALLMWVLLPTKPFQWIAMLWLLLPF
FPPRTIIQAGEAKIDVLDVGQGLAVAIRTQHHVLLYDTGDRFFQGNDLGKMVILPYLNTLGIKKIDTIVVSHPDKDHLGG
LKSLEKEIPVERLLVNEPHFYHRGLKCHDYPPWQWDGVSFRFLPIKIPLRGKNNSSCILQIETHAGRMLLAGDIEKIAED
YLVQTYGNILESDVLLVPHHGSKTSSSYRFLLEVAPLYAIASLGFDNRFHFPHDKTLANMKKLNIPFYRTDTCGMVQITL
PAQGALTHPTCFSGQRLQPV

Nucleotide

• Length: 2223 bp

>NTDB_id=393362 GCS73_RS13385 WP_003635596.1 2971058..2973280(+) (comEC) [Legionella longbeachae strain B41211CHC]
ATGGAAATTTTTTGCTTTTTTATAGGCATATTGTATCGATATACCTTACACGGATTATTGCCTATACTTATTTTATTTAT
TTTTTTCATTATTCCCAGGTATGCGAATATCCTGTTTTTTCTTTTAGGCATCTTCATCGCGACTGTGCACCAATCTCAAA
ATTTACCAAAAGGATTACCCGATGTTGAAGTAATACCCCAAGTCAGCATCCAAGGAACAATTGCATCTATTCCGCTCCAA
AGTCCATCTAAGACACTCTTTTTATTGGCTTTAGAACAATACGACAATCATCCAGCACAAGGGATAATACAATTATCATG
GTATAACAAAGCCCCCAAAATCCATGTAGGGCAACGATGGAAATTTAAAGTGAAATTGAAAAAGCCAAGAAATTATCTAA
ATCCAGGGAGTATGGATTATGTACGTTCACTCGCAACACGCCATATATTGTGGACTGGATATATTCATTCTAGAGGAAAT
AAGCAACTCCCAAAAGTCCCCTCATCTTTCAATTGGCTAGAACTAAGGGAACAATTAAGCGAGCAACTCGGCTTGTTGGC
ACCTGATCAAAAAACCGCTGGAATTGTAGAGGCTTTAGCTTTAAATATAACAACCCATATTGACCAGAAAAGCTGGGATT
TGTTTAGACGTACTGGCACAACCCATTTATTTGGTATTTCAGGTGAACATATCGCCTTAATTTCAGGTATTATTTATTGG
TTACTCCGTTGGATATGGACTCGAAGCTCTCGTCTTTGCTTACGCATTCCAGCCCCTCATATTGCAAGTATGGGTGGCCT
TTTGGCTGCATCAGGATATGCGTTTTTAGCAGGTTTTGCACCTCCTGTCCAAAGGGCACTTATCGGATGTTTTTTTTATA
CCCTTTATAGCTTGGGCTACCAGCGTTTTACTCCATGGCAAGTATGGCGCTATGCTCTATGTGGTGTCTTATTGATTGAA
CCACATGCCGTATTTATGCAAGGATTCTATTTTTCTTTTCTTGCAGTAGCATGCTTGCTCTTAACACAACAACGCTGGCG
TTTAAAAGGATATAAAGCCTCTTTAGCCCTACAGTTAAGCTGTTTAATTGGGTTAATGCCCCTAACCTTATATTGGTATG
CTTATGGCTCAATTAATGGATTTATTGCAAACCTTTTCGCTATACCTTTGGTGGGATTACTCATTGTTCCGTTGTCATTA
ATGACAATGACGGTCAGCTCTTTAAGCATTGCAAAGATACTAATGAAGGCCGTTTCTTTACTCATTACCCTATTGTTTAA
AGGGCTATCCTTGTCAGAATATTTAGCTGCTCTAAATATTAATTGCCCCATTTATTCTATAGAACTGGCTCTTGTTCTAA
TTGGAGCTTTATTGATGTGGGTTTTACTACCCACTAAACCTTTTCAATGGATCGCGATGCTTTGGTTATTGCTCCCGTTT
TTTCCACCGCGAACAATCATTCAAGCAGGCGAAGCCAAAATAGATGTTTTGGACGTAGGGCAAGGCTTGGCTGTTGCGAT
TCGAACGCAACACCATGTATTGCTTTATGATACAGGAGATCGTTTCTTTCAAGGAAATGATTTAGGGAAAATGGTTATTT
TGCCTTATCTTAACACTTTGGGTATCAAAAAAATTGATACCATAGTTGTGAGCCATCCTGATAAAGATCATCTTGGAGGA
CTTAAATCACTGGAAAAAGAAATACCAGTAGAGAGGCTATTAGTCAATGAGCCTCATTTCTATCATCGTGGTTTAAAATG
TCATGATTATCCACCATGGCAATGGGACGGTGTTTCGTTCCGTTTTCTGCCAATAAAAATTCCCCTTAGAGGAAAAAACA
ACAGTTCTTGCATTTTACAAATAGAAACACATGCAGGACGGATGCTCTTAGCTGGCGATATTGAAAAAATAGCTGAAGAT
TATCTGGTGCAGACTTATGGCAATATTCTTGAATCAGATGTGCTGCTTGTTCCTCATCATGGCAGTAAAACTTCATCATC
CTACAGATTCTTATTAGAAGTTGCTCCGCTCTATGCTATAGCCTCCCTGGGCTTTGATAATCGCTTTCACTTTCCCCATG
ACAAGACTTTAGCAAACATGAAAAAACTGAATATCCCTTTTTACAGAACAGATACTTGTGGCATGGTACAGATTACTTTG
CCTGCCCAAGGAGCACTCACTCATCCCACTTGCTTTAGTGGACAGAGGTTACAACCCGTGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (201-465)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-676)

• Domain of unknown function (DUF4131) (DUF4131) (16-157)

3D structure

• AlphaFold DB: D3HKP4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Legionella pneumophila strain Lp02	64.305	99.189	0.638
comEC	Legionella pneumophila strain ERS1305867	63.81	99.324	0.634