Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NLA_RS00295 Genome accession   NC_014752
Coordinates   66536..67723 (+) Length   395 a.a.
NCBI ID   WP_013448200.1    Uniprot ID   E4Z9V5
Organism   Neisseria lactamica 020-06     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 61536..72723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLA_RS00280 (NLA_0530) - 62462..63061 (+) 600 WP_013448197.1 DUF4390 domain-containing protein -
  NLA_RS00285 (NLA_0540) - 63061..65166 (+) 2106 WP_013448198.1 HAMP domain-containing histidine kinase -
  NLA_RS00290 (NLA_0550) - 65171..66445 (+) 1275 WP_013448199.1 sigma-54-dependent transcriptional regulator -
  NLA_RS00295 (NLA_0560) dprA 66536..67723 (+) 1188 WP_013448200.1 DNA-processing protein DprA Machinery gene
  NLA_RS00300 (NLA_0570) - 67749..68210 (+) 462 WP_002215351.1 DUF494 domain-containing protein -
  NLA_RS00305 (NLA_0580) topA 68282..70588 (+) 2307 WP_013448201.1 type I DNA topoisomerase -
  NLA_RS00310 (NLA_0590) - 70706..71332 (-) 627 WP_013448202.1 DUF481 domain-containing protein -
  NLA_RS00315 (NLA_0600) - 71540..71917 (+) 378 WP_003679508.1 helix-turn-helix domain-containing protein -
  NLA_RS00320 (NLA_0610) rsmD 72006..72575 (+) 570 WP_013448203.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -

Sequence

Protein


Download         Length: 395 a.a.        Molecular weight: 41900.00 Da        Isoelectric Point: 6.2536

>NTDB_id=39049 NLA_RS00295 WP_013448200.1 66536..67723(+) (dprA) [Neisseria lactamica 020-06]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSAQNALSAPAEQVAQAVRHKQALEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLAQGLTAPPVLFLRGNVRLLHKPSAAIVGSRYATPQAMRIAKDFGRALGGKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPANKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTSDTGSRAVQT
AYAPPPAAKMLSEGAAGGTAVGGILDKMGFDPVHPDVLAGQLAMPATDLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide


Download         Length: 1188 bp        

>NTDB_id=39049 NLA_RS00295 WP_013448200.1 66536..67723(+) (dprA) [Neisseria lactamica 020-06]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACACCCTATATCGGCGCAGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGCAAAATGCCTTGTCCGCACCGGCGGAACAGGTTGCCCAGGCGGTGCGGCACAAGCAGGCGC
TTGAGGCTTGGCGCAATGCGGAAAAACGCGCCTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGTCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGGCGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATTGTCGGCAGCCGCTATGCCACGCCGCAGGCCATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGTGGGAAAGGCATTCCCGTTGTGTCGGGTATGGCTTCGGGCATCGATACC
GCCGCCCATCAGGGTGCGTTGCAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GGCCAACAAAAACCTTGCTTATGAAATCGCCGAAAAAGGATTGATTGTCAGCGAGTTCCCCATCGGCACGCGGCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCCCTGTCGCAGGTTACGCTGGTGGTTGAAGCCGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGCTCGATAGACAATCCGCA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GGCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGTCCGACACGGGCAGCCGCGCCGTTCAGACG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCTGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCGTCCATCCCGACGTGCTTGCCGGGCAGCTTGCTATGCCTGCCACAGATTTGTATGCCGCACTGT
TGGAATTGGAACTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(343-388)

DNA recombination-mediator protein A (DNA_processg_A)

(79-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E4Z9V5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Neisseria gonorrhoeae strain FA1090

96.709

100

0.967
  dprA Neisseria gonorrhoeae MS11

96.456

100

0.965
  dprA Neisseria meningitidis strain C311

89.924

100

0.904
  dprA Neisseria meningitidis MC58

89.924

100

0.904
  dprA Vibrio cholerae strain A1552

37.975

100

0.38

Multiple sequence alignment