Detailed information NTG0390418

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: FSA28_RS01445
• Genome accession: NZ_CP044495
• Coordinates: 294516..296798 (+)
• Length: 760 a.a.
• NCBI ID: WP_002266017.1
• Uniprot ID: A0AAX1K0V4
• Organism: Streptococcus mutans strain UA140
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 289516..301798

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA28_RS01400 (FSA28_0068)	-	290021..290296 (+)	276	WP_014678243.1	hypothetical protein	-
FSA28_RS10385 (FSA28_0070)	-	290510..290692 (+)	183	WP_014678242.1	hypothetical protein	-
FSA28_RS01410 (FSA28_0071)	-	290973..291191 (+)	219	WP_014678241.1	Blp family class II bacteriocin	-
FSA28_RS01415 (FSA28_0072)	-	291219..291626 (+)	408	WP_002292281.1	hypothetical protein	-
FSA28_RS01425 (FSA28_0074)	-	291893..292054 (+)	162	WP_162470319.1	hypothetical protein	-
FSA28_RS01430	-	292528..292737 (+)	210	WP_002292070.1	hypothetical protein	-
FSA28_RS01435 (FSA28_0076)	-	292975..293253 (+)	279	WP_002310898.1	hypothetical protein	-
FSA28_RS01445 (FSA28_0077)	comA/nlmT	294516..296798 (+)	2283	WP_002266017.1	peptide cleavage/export ABC transporter	Regulator
FSA28_RS01450 (FSA28_0078)	comB/nlmE	296812..297714 (+)	903	WP_002263524.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
FSA28_RS01455 (FSA28_0079)	-	298087..299751 (+)	1665	WP_002291675.1	transcription antiterminator	-
FSA28_RS01460 (FSA28_0080)	ulaG	300328..301419 (+)	1092	WP_002291674.1	L-ascorbate 6-phosphate lactonase	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 85082.76 Da
• Isoelectric Point: 8.9095

>NTDB_id=390418 FSA28_RS01445 WP_002266017.1 294516..296798(+) (comA/nlmT) [Streptococcus mutans strain UA140]
MKQVIYVVLIVIAVNILLEVIKRVTKRGGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIA
YLRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPS
VKVTRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEY
IPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQII
DAVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMET
IKSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSN
PIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLV
GASGSGKTTLAKLIVNFYEPNKGIVRINGNDLKVIDKTALRRHISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACE
IAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILTEKKIISNLLQMTEKTIIFVAH
RLSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2283 bp

>NTDB_id=390418 FSA28_RS01445 WP_002266017.1 294516..296798(+) (comA/nlmT) [Streptococcus mutans strain UA140]
ATGAAACAAGTTATTTATGTTGTTTTAATCGTCATAGCCGTTAACATTCTCTTAGAGGTTATCAAAAGAGTAACAAAAAG
GGGAGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTAGTAC
CTCAGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTACGGATCTAACTACTCTATCGCT
TATCTGCGGGAACTCTCAAAGACTAACAAGCAGGGAACAACAGCTCTTGGCATTGTTGAAGCTGCTAAAAAGTTAGGCTT
TGAAACACGCTCTATCAAGGCGGATATGACGCTTTTTGATTATAATGATTTGACCTATCCTTTTATCGTCCATGTGATTA
AAGGAAAACGTCTTCAGCATTATTATGTCGTCTATGGCAGCCAGAATAATCAGCTGATTATTGGAGATCCTGATCCTTCA
GTTAAGGTGACTAGGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGCCTTGCAATTTTCCTAGCTCCTCAGCCTAA
CTATAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCTAATTTCTTCCCGTTGATCTTTAAGCAGAAAGCTTTGATGACTT
ATATTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTAC
ATTCCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGGTCATGGC
TTTTGCAAAAGAATACCTCTTGGCCGTACTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATCAAACATATTT
TTACGCTTCCTATGTCTTTCTTTGCGACAAGGCGAACAGGAGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATT
GATGCTGTAGCGTCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTAATTTTGGTTGGTGGGGTTTTGTTGGCGCA
AAACAATAACCTTTTCTTTCTAACCTTGCTCTCCATTCCGATTTATGCCATCATTATTTTTGCTTTCTTGAAACCCTTTG
AGAAAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGATATCAATGGGATGGAAACC
ATTAAATCACTCACAAGTGAGTCCGCTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAA
GCTACACAAGTATAGTGCCATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATCCTCAATGTTGTCATTCTATGGTATG
GCTCTCGTCTAGTTATGGATAATAAAATCTCAGTTGGTCAGCTTATCACCTTTAATGCTTTGCTGTCTTATTTCTCAAAT
CCAATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAGGTCTATCT
TGTCGAATCTGAATTTGAAAAAGACGGCGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAAAATCTTT
CTTATAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGTCTAGTT
GGAGCCAGTGGTTCTGGTAAAACAACTTTGGCTAAACTGATTGTCAATTTCTACGAGCCTAACAAGGGGATTGTTCGAAT
CAATGGCAATGATTTAAAAGTTATTGATAAGACAGCTTTGCGGCGGCATATTAGCTATTTGCCGCAACAGGCCTATGTTT
TTAGTGGCTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCTTGTGAA
ATTGCTGAAATCCGCTCGGACATTGAACAAATGCCTCAGGGCTATCAGACAGAGTTATCAGATGGTGCCGGTATTTCTGG
CGGTCAAAAACAGCGGATTGCTTTAGCTAGGGCCTTATTAACACAGGCACCGGTTTTGATTCTGGATGAAGCCACCAGCA
GTCTTGATATTTTGACAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACAATAATTTTTGTTGCCCAC
CGCTTAAGCATTTCACAGCGTACTGACGAAGTCATTGTCATGGATCAAGGAAAAATTGTTGAACAAGGCACTCATAAGGA
ACTTTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (50-186)

• ABC transporter (ABC_tran) (544-693)

• ABC transporter transmembrane region (ABC_membrane) (212-481)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	99.868	100	0.999
comA	Streptococcus mitis NCTC 12261	65.411	94.342	0.617
comA	Streptococcus pneumoniae Rx1	64.854	94.342	0.612
comA	Streptococcus pneumoniae D39	64.854	94.342	0.612
comA	Streptococcus pneumoniae R6	64.854	94.342	0.612
comA	Streptococcus mitis SK321	64.714	94.342	0.611
comA	Streptococcus pneumoniae TIGR4	64.575	94.342	0.609
comA	Streptococcus gordonii str. Challis substr. CH1	64.435	94.342	0.608