Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FSA28_RS01255 Genome accession   NZ_CP044495
Coordinates   257550..258272 (+) Length   240 a.a.
NCBI ID   WP_002276223.1    Uniprot ID   -
Organism   Streptococcus mutans strain UA140     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 252550..263272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA28_RS01240 (FSA28_0037) - 252951..254504 (-) 1554 WP_002290673.1 ABC transporter substrate-binding protein/permease -
  FSA28_RS01245 (FSA28_0038) - 254656..256557 (+) 1902 WP_002290676.1 DUF2207 domain-containing protein -
  FSA28_RS01250 (FSA28_0039) - 256615..257460 (+) 846 WP_002262750.1 undecaprenyl-diphosphate phosphatase -
  FSA28_RS01255 (FSA28_0040) mecA 257550..258272 (+) 723 WP_002276223.1 adaptor protein MecA Regulator
  FSA28_RS01260 (FSA28_0041) rgpG 258278..259438 (+) 1161 WP_002262748.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  FSA28_RS01265 (FSA28_0042) sufC 259512..260282 (+) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  FSA28_RS01270 (FSA28_0043) sufD 260320..261582 (+) 1263 WP_002290677.1 Fe-S cluster assembly protein SufD -
  FSA28_RS01275 (FSA28_0044) - 261587..262816 (+) 1230 WP_002270784.1 cysteine desulfurase -
  FSA28_RS01280 (FSA28_0045) sufU 262803..263237 (+) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27997.61 Da        Isoelectric Point: 4.2574

>NTDB_id=390415 FSA28_RS01255 WP_002276223.1 257550..258272(+) (mecA) [Streptococcus mutans strain UA140]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPENFKNSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEIEKREEEKTQQEKGETKEKRDYVHFVLDFPNIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=390415 FSA28_RS01255 WP_002276223.1 257550..258272(+) (mecA) [Streptococcus mutans strain UA140]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATGCTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGAACAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCCCCGGAGGATTTCTTTAATACCTT
GGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAGGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTAATATTCAGCAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCGAAGATAAACCTGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

98.75

100

0.988
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.571

100

0.496
  mecA Streptococcus pneumoniae D39

48.571

100

0.496
  mecA Streptococcus pneumoniae R6

48.571

100

0.496
  mecA Streptococcus pneumoniae TIGR4

48.571

100

0.496

Multiple sequence alignment