Detailed information NTG0390340

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: FSA31_RS09920
• Genome accession: NZ_CP044492
• Coordinates: 1973841..1975049 (+)
• Length: 402 a.a.
• NCBI ID: WP_002284612.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain T8
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1972702..1973559	1973841..1975049	flank	282

Gene organization within MGE regions

Location: 1972702..1975049

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA31_RS09915 (FSA31_1956)	-	1972702..1973595 (-)	894	WP_076611617.1	IS982-like element ISSmu5 family transposase	-
FSA31_RS09920 (FSA31_1957)	htrA	1973841..1975049 (+)	1209	WP_002284612.1	trypsin-like peptidase domain-containing protein	Regulator

Sequence

Protein

• Length: 402 a.a.
• Molecular weight: 43143.61 Da
• Isoelectric Point: 8.1800

>NTDB_id=390340 FSA31_RS09920 WP_002284612.1 1973841..1975049(+) (htrA) [Streptococcus mutans strain T8]
MNNTKSHPFLKWFIPFLVIFLTFILGVISTLTFNWITGNKSFSNNEKTTVSNVIYDTKSNTTKAVKNVKNTVVSVINYQK
TDNSYYNYDSGSQEKNKSEDGLGVYGEGSGVIYKKDGDSAYLVTNNHVVKDAEKLEIMMANGKKVVGKLVGSDTYSDLAV
IKISSKYVTTVAEFANSDKIKVGEPAIAIGSPLGSDYANSVTEGIVSSLSRTVTSQNENGETISTNAIQTDAAINPGNSG
GALINIKGQVIGINSSKIASSNNSNSGVAVEGMGFAIPSNDVVSIINQLEENGEVVRPALGISMANLSEASTSGRDTLKI
PSDVTSGIVVLSTQSGMPADGKLKKYDVITEIDGKKVASISDLQSILYKHKKGDKIKLTFYREKDKQTVEIQLTKTSQDL
NH

Nucleotide

• Length: 1209 bp

>NTDB_id=390340 FSA31_RS09920 WP_002284612.1 1973841..1975049(+) (htrA) [Streptococcus mutans strain T8]
GTGAATAATACGAAATCTCACCCTTTTTTAAAATGGTTTATACCTTTTTTAGTTATTTTTTTAACTTTTATTTTAGGGGT
CATATCAACACTTACCTTTAATTGGATAACTGGTAACAAATCGTTTTCTAACAATGAAAAAACAACTGTTAGTAATGTCA
TTTATGATACCAAATCTAACACTACCAAGGCTGTTAAAAATGTCAAAAATACAGTTGTATCTGTCATCAATTATCAAAAA
ACAGATAATAGTTATTACAATTATGACAGCGGTTCTCAAGAAAAAAATAAATCAGAGGATGGTCTAGGAGTCTACGGTGA
AGGTTCTGGTGTTATCTACAAAAAAGATGGCGATAGTGCTTATTTAGTCACAAACAATCATGTCGTTAAAGATGCAGAAA
AGTTAGAAATCATGATGGCTAATGGTAAAAAAGTTGTCGGTAAATTAGTAGGTTCTGATACTTATTCTGATCTGGCTGTT
ATTAAAATTTCTTCTAAGTATGTTACGACAGTTGCTGAATTTGCTAATTCGGATAAAATAAAAGTTGGAGAACCAGCAAT
CGCTATTGGTAGCCCTTTAGGCAGTGATTATGCTAATTCTGTAACAGAAGGAATTGTTTCAAGTCTCAGTCGTACAGTAA
CTTCACAAAATGAAAATGGCGAAACAATTTCAACTAATGCTATTCAAACAGACGCAGCTATTAACCCTGGTAATTCTGGT
GGCGCTTTAATTAATATCAAAGGACAAGTTATTGGTATCAATTCAAGTAAAATTGCATCAAGTAATAACTCAAATAGTGG
CGTTGCTGTTGAAGGAATGGGCTTTGCAATTCCTTCAAACGATGTTGTCTCTATTATTAATCAATTAGAAGAAAATGGTG
AAGTTGTTAGACCCGCTCTTGGTATTTCAATGGCTAATCTTAGTGAAGCTTCAACAAGTGGAAGAGATACTTTAAAAATA
CCAAGTGATGTCACAAGCGGTATTGTTGTTCTTTCAACACAAAGTGGTATGCCAGCAGATGGGAAGCTGAAGAAATATGA
TGTCATTACAGAAATTGATGGGAAGAAGGTAGCGTCTATCAGCGATCTTCAAAGTATTCTTTACAAACACAAAAAGGGAG
ATAAAATTAAACTCACTTTCTATCGCGAAAAAGATAAACAAACAGTTGAGATCCAATTAACTAAAACAAGTCAAGATTTG
AATCATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

• PDZ domain (PDZ_2) (298-393)

• Peptidase family M50 (Peptidase_M50) (212-398)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	99.751	100	0.998
htrA	Streptococcus gordonii str. Challis substr. CH1	56.14	99.254	0.557
htrA	Streptococcus mitis NCTC 12261	54.315	98.01	0.532
htrA	Streptococcus pneumoniae Rx1	54.315	98.01	0.532
htrA	Streptococcus pneumoniae D39	54.315	98.01	0.532
htrA	Streptococcus pneumoniae R6	54.315	98.01	0.532
htrA	Streptococcus pneumoniae TIGR4	54.315	98.01	0.532