Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FSA31_RS05250 Genome accession   NZ_CP044492
Coordinates   1071790..1072464 (-) Length   224 a.a.
NCBI ID   WP_002264509.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1066790..1077464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS05225 (FSA31_1033) - 1067099..1068376 (-) 1278 WP_002284418.1 pyrimidine-nucleoside phosphorylase -
  FSA31_RS05230 (FSA31_1034) - 1068485..1069081 (-) 597 WP_002270201.1 class I SAM-dependent methyltransferase -
  FSA31_RS05235 (FSA31_1035) coaA 1069177..1070097 (+) 921 WP_002262217.1 type I pantothenate kinase -
  FSA31_RS05240 (FSA31_1036) rpsT 1070151..1070405 (+) 255 WP_011074586.1 30S ribosomal protein S20 -
  FSA31_RS05245 (FSA31_1037) ciaH 1070493..1071800 (-) 1308 WP_002264510.1 three-component system sensor histidine kinase CiaH Regulator
  FSA31_RS05250 (FSA31_1038) ciaR 1071790..1072464 (-) 675 WP_002264509.1 three-component system response regulator CiaR Regulator
  FSA31_RS05255 (FSA31_1039) ciaX 1072515..1072778 (-) 264 WP_002262213.1 three-component system regulator CiaX -
  FSA31_RS05260 (FSA31_1041) - 1073179..1075728 (-) 2550 WP_002284419.1 M1 family metallopeptidase -
  FSA31_RS05265 (FSA31_1042) phoU 1075769..1076422 (-) 654 WP_002262211.1 phosphate signaling complex protein PhoU -
  FSA31_RS05270 (FSA31_1043) pstB 1076454..1077212 (-) 759 WP_002262210.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25417.19 Da        Isoelectric Point: 4.3777

>NTDB_id=390298 FSA31_RS05250 WP_002264509.1 1071790..1072464(-) (ciaR) [Streptococcus mutans strain T8]
MIKLLLVEDDLSLSNSIFDFLDDFADVMQVFDGAEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENNLTYGELTVDTATNTTMVNGKEVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKDTTFGKNLQTLRSVGYILKDAN

Nucleotide


Download         Length: 675 bp        

>NTDB_id=390298 FSA31_RS05250 WP_002264509.1 1071790..1072464(-) (ciaR) [Streptococcus mutans strain T8]
ATGATAAAGTTATTATTAGTAGAAGACGATTTGAGTCTATCTAACTCTATCTTTGACTTTCTGGATGATTTTGCTGATGT
CATGCAGGTTTTTGATGGTGCAGAAGGACTGTATGAAGCAGAGAGTGGCGTTTATGATTTGATTCTATTAGACTTAATGC
TTCCTGAAAAAAATGGCTTCCAAGTTTTAAAAGAACTGCGTGAAAAAGGGATAACGACACCTGTTTTGATTATGACAGCT
AAGGAAGGTTTGGATGACAAAGGACACGGTTTTGAATTAGGAGCTGATGATTATCTGACAAAACCATTTTATCTTGAAGA
ATTAAAAATGCGTATTCAGGCCCTCCTCAAACGTTCAGGCAAATTCAACGAAAATAATCTGACTTACGGTGAGTTAACCG
TTGATACAGCAACTAATACAACAATGGTAAATGGAAAAGAAGTTGAACTGCTTGGCAAAGAGTTTGACTTATTAGTTTAT
TTCTTACAAAATCAAAATGTCATTTTACCTAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGCGATACGACAAT
TTCGGTTGTTGAAGTCTATGTTTCTAAAATAAGAAAAAAATTAAAAGATACCACATTTGGAAAGAATTTACAGACATTAC
GCAGTGTAGGATATATTTTGAAGGATGCTAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

99.554

100

0.996
  ciaR Streptococcus pneumoniae Rx1

87.946

100

0.879
  ciaR Streptococcus pneumoniae D39

87.946

100

0.879
  ciaR Streptococcus pneumoniae R6

87.946

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.611

100

0.379
  vicR Streptococcus mutans UA159

35.622

100

0.371

Multiple sequence alignment