Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FSA31_RS01230 Genome accession   NZ_CP044492
Coordinates   259109..259831 (+) Length   240 a.a.
NCBI ID   WP_002284705.1    Uniprot ID   -
Organism   Streptococcus mutans strain T8     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 254109..264831
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA31_RS01215 (FSA31_0246) - 254509..256062 (-) 1554 WP_002266996.1 ABC transporter substrate-binding protein/permease -
  FSA31_RS01220 (FSA31_0247) - 256215..258116 (+) 1902 WP_002284707.1 DUF2207 domain-containing protein -
  FSA31_RS01225 (FSA31_0248) - 258174..259019 (+) 846 WP_002284706.1 undecaprenyl-diphosphate phosphatase -
  FSA31_RS01230 (FSA31_0249) mecA 259109..259831 (+) 723 WP_002284705.1 adaptor protein MecA Regulator
  FSA31_RS01235 (FSA31_0250) rgpG 259837..260997 (+) 1161 WP_002262748.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  FSA31_RS01240 (FSA31_0251) sufC 261071..261841 (+) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  FSA31_RS01245 (FSA31_0252) sufD 261879..263141 (+) 1263 WP_151416601.1 Fe-S cluster assembly protein SufD -
  FSA31_RS01250 (FSA31_0253) - 263146..264375 (+) 1230 WP_002284703.1 cysteine desulfurase -
  FSA31_RS01255 (FSA31_0254) sufU 264362..264796 (+) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28014.60 Da        Isoelectric Point: 4.2340

>NTDB_id=390273 FSA31_RS01230 WP_002284705.1 259109..259831(+) (mecA) [Streptococcus mutans strain T8]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEVEKREEEKTQQEKGETKEKRDYVHFVLDFPNIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=390273 FSA31_RS01230 WP_002284705.1 259109..259831(+) (mecA) [Streptococcus mutans strain T8]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATACTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGGACAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCTCCGGAGGATTTCTTTAATACCTT
GGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAGTTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAGGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTAATATTCAGCAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TCTGCTTAATCTCGAAGATAAACCTGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

99.167

100

0.992
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.98

100

0.5
  mecA Streptococcus pneumoniae D39

48.98

100

0.5
  mecA Streptococcus pneumoniae R6

48.98

100

0.5
  mecA Streptococcus pneumoniae TIGR4

48.98

100

0.5

Multiple sequence alignment