Detailed information NTG0389841

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: F3I00_RS02870
• Genome accession: NZ_CP044412
• Coordinates: 586508..588667 (+)
• Length: 719 a.a.
• NCBI ID: WP_003649216.1
• Uniprot ID: A0AB33C8C0
• Organism: Lactobacillus sp. JM1
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 581508..593667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F3I00_RS02845 (F3I00_02850)	udk	581932..582567 (-)	636	WP_003649222.1	uridine kinase	-
F3I00_RS02850 (F3I00_02855)	-	582729..584096 (+)	1368	WP_020806830.1	MFS transporter	-
F3I00_RS02855 (F3I00_02860)	-	584239..584391 (+)	153	WP_003649220.1	hypothetical protein	-
F3I00_RS02860 (F3I00_02865)	-	584382..585701 (+)	1320	WP_231110767.1	sensor histidine kinase	-
F3I00_RS02865 (F3I00_02870)	-	585698..586495 (+)	798	WP_003649217.1	LytTR family DNA-binding domain-containing protein	-
F3I00_RS02870 (F3I00_02875)	comA	586508..588667 (+)	2160	WP_003649216.1	peptide cleavage/export ABC transporter	Regulator
F3I00_RS02875 (F3I00_02880)	-	588678..589271 (+)	594	WP_003649215.1	HlyD family efflux transporter periplasmic adaptor subunit	-
F3I00_RS02885 (F3I00_02890)	-	589573..589800 (+)	228	WP_049159833.1	Blp family class II bacteriocin	-
F3I00_RS02890 (F3I00_02895)	-	589810..590007 (+)	198	WP_003649213.1	Blp family class II bacteriocin	-
F3I00_RS02900	-	590570..590716 (+)	147	WP_156235821.1	hypothetical protein	-
F3I00_RS02905 (F3I00_02905)	-	591083..591367 (+)	285	WP_003649210.1	bacteriocin immunity protein	-
F3I00_RS02910 (F3I00_02910)	-	591523..591720 (+)	198	WP_020806826.1	hypothetical protein	-
F3I00_RS02915 (F3I00_02915)	-	591734..591964 (+)	231	WP_003649208.1	hypothetical protein	-
F3I00_RS02920 (F3I00_02920)	-	592148..592462 (+)	315	WP_159310976.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 719 a.a.
• Molecular weight: 81069.37 Da
• Isoelectric Point: 7.7712

>NTDB_id=389841 F3I00_RS02870 WP_003649216.1 586508..588667(+) (comA) [Lactobacillus sp. JM1]
MLFKYKSVYVPQVDEMDCGVACLAMILKQYHSRVSLAHLRHEARTNLEGTTALGLVKTAQKFNFKTEAVKADMSLFDENS
IQYPFIAHVLKQGELLHYYVVLKNAKNYLVIADPDPSVGVVKMPKDKFAQEWTGVALFMVPNEDFEPIKEKKNNLWSLFP
YMFKQKRLMINIILAALLMTIISICSSYFVQGIIDTYIPDGTYQTLSILAVGLLIAYVFNSIFSYGQNFLLNILGQRLSI
DLNLRYIRHIFELPMEFFVTRRTGEITSRFSDASRIIDALASTVISLFLDLSIVIVMGLVLAAQNMTLFGITLLALPIYA
VVILGFTKKFEKLNNEQMESNAVLSSSVIEDIQGIETIKALNSENTRYRRIDSQFVDYLKKSFKYSKTESLQTALKTFIQ
LSLNVIVLWVGAKIVMQGQLSIGQLMTFNALLAYFIDPLQSIINLQPRLQSASVAQNRLNEVYQVKSEFNQKATIEDRKL
LEGNIEYKNVDYSYGYGTDVLKDINLKISQGEKLTIVGMSGSGKSTMVKLLVDFFSPSKGQVTLNGHATSEIDKHTLRSY
VNYVPQTPYIFSGTVKENLLLGCRPDITEEDVIKACQIAEIDQEIANLPLQFETKLDENAKILSGGQKQRLTIARALLSP
AKVFIFDEVTSGLDTITEKKVIDNLMKLKDKTIIFIAHRLAIAERADKVVVIDHGQIVEEGSHSELMSKHGFYYDLVKG

Nucleotide

• Length: 2160 bp

>NTDB_id=389841 F3I00_RS02870 WP_003649216.1 586508..588667(+) (comA) [Lactobacillus sp. JM1]
ATGTTATTCAAATATAAATCCGTATACGTGCCACAAGTGGATGAGATGGATTGCGGCGTTGCTTGTCTAGCAATGATCTT
AAAGCAATATCATTCTCGCGTATCTTTAGCACATTTACGTCATGAAGCTCGTACTAATCTTGAAGGCACAACTGCTTTAG
GACTAGTGAAGACAGCACAAAAATTTAATTTCAAAACAGAAGCCGTAAAAGCAGATATGTCTTTATTTGATGAGAATAGT
ATTCAATATCCTTTTATTGCCCACGTCCTAAAACAAGGAGAACTACTTCATTATTACGTAGTTCTTAAAAATGCTAAGAA
TTATTTAGTAATTGCAGATCCTGATCCATCAGTTGGTGTAGTAAAGATGCCAAAAGACAAATTTGCTCAAGAATGGACTG
GTGTTGCACTCTTTATGGTTCCTAACGAAGACTTTGAACCAATCAAAGAAAAGAAGAATAATTTATGGTCTCTCTTTCCA
TATATGTTTAAACAAAAGCGGCTGATGATTAACATCATTTTAGCCGCTTTATTAATGACCATAATTAGTATCTGTAGTTC
ATATTTTGTTCAAGGAATAATTGATACTTACATTCCAGATGGAACCTATCAGACTCTTTCGATCTTAGCTGTTGGACTAT
TAATTGCTTATGTCTTTAATTCAATTTTTTCTTATGGACAGAATTTTTTATTAAATATTTTAGGTCAAAGATTAAGTATT
GATCTAAATCTGCGATACATCAGGCATATTTTTGAATTACCAATGGAATTCTTTGTAACAAGAAGAACGGGTGAAATTAC
TTCGCGTTTTTCTGATGCAAGTAGAATTATTGACGCTTTGGCAAGTACAGTTATTTCGCTCTTCTTAGACCTCTCAATTG
TGATTGTGATGGGATTAGTCTTAGCAGCACAAAATATGACATTATTTGGGATTACACTGTTAGCTTTGCCTATTTATGCA
GTTGTAATTCTAGGTTTTACTAAAAAGTTTGAAAAACTAAATAACGAACAAATGGAAAGTAATGCTGTTTTGAGTTCTTC
AGTTATTGAAGATATTCAAGGAATTGAAACTATTAAAGCTTTAAATAGTGAGAATACAAGATATAGAAGAATCGACAGTC
AGTTTGTAGATTACTTAAAGAAGTCATTTAAATATAGTAAGACTGAGAGTTTACAGACAGCACTCAAGACATTTATTCAA
TTATCTCTTAATGTAATTGTTCTTTGGGTTGGTGCAAAGATTGTAATGCAAGGACAATTGAGCATTGGTCAGTTAATGAC
GTTCAATGCATTGCTGGCATATTTCATTGATCCCTTGCAAAGTATTATTAATTTACAACCGCGACTTCAATCAGCTAGTG
TTGCTCAAAATCGATTAAATGAGGTCTATCAAGTAAAAAGTGAATTCAATCAGAAGGCTACTATTGAAGATCGTAAGCTC
CTAGAAGGAAATATTGAATATAAGAATGTGGATTATAGCTATGGTTATGGCACAGATGTCTTAAAAGATATTAATCTCAA
AATTAGCCAGGGCGAAAAATTAACGATTGTTGGAATGAGTGGTTCTGGAAAATCTACGATGGTTAAGTTGTTAGTAGATT
TCTTTTCGCCAAGTAAAGGTCAGGTTACATTAAATGGACATGCAACAAGTGAGATTGATAAGCATACGTTGCGGTCATAT
GTAAATTATGTACCTCAAACTCCATATATCTTTTCTGGAACAGTTAAAGAGAATTTGTTGTTAGGTTGTAGGCCAGATAT
CACTGAAGAAGATGTAATAAAGGCTTGTCAAATTGCTGAGATTGACCAAGAAATAGCTAATCTACCTTTGCAATTTGAAA
CAAAATTAGATGAAAATGCCAAAATTTTATCTGGTGGACAAAAACAAAGGTTAACTATTGCCCGGGCATTACTATCTCCT
GCAAAGGTATTTATTTTTGATGAAGTAACAAGTGGCTTAGATACAATTACTGAGAAGAAAGTGATTGATAATTTGATGAA
GCTAAAGGATAAGACAATTATCTTTATTGCGCATCGACTAGCAATTGCAGAACGGGCAGACAAGGTAGTTGTAATTGATC
ATGGTCAAATAGTTGAAGAAGGCAGCCACAGCGAATTGATGAGTAAGCATGGTTTTTACTATGACTTAGTGAAGGGATAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (501-651)

• Peptidase C39 family (Peptidase_C39) (7-143)

• ABC transporter transmembrane region (ABC_membrane) (169-439)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	57.725	99.026	0.572
comA	Streptococcus mitis SK321	57.444	99.026	0.569
comA	Streptococcus pneumoniae Rx1	57.303	99.026	0.567
comA	Streptococcus pneumoniae D39	57.303	99.026	0.567
comA	Streptococcus pneumoniae R6	57.303	99.026	0.567
comA	Streptococcus pneumoniae TIGR4	57.163	99.026	0.566
comA	Streptococcus gordonii str. Challis substr. CH1	55.478	99.026	0.549
comA/nlmT	Streptococcus mutans UA159	53.748	98.331	0.529