Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   LPB220_RS02805 Genome accession   NZ_CP044230
Coordinates   528031..529902 (+) Length   623 a.a.
NCBI ID   WP_150905434.1    Uniprot ID   A0A5J6LL56
Organism   Streptococcus sp. LPB0220     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 523031..534902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB220_RS02790 (LPB220_02790) fmt 525034..525969 (+) 936 WP_150905430.1 methionyl-tRNA formyltransferase -
  LPB220_RS02795 (LPB220_02795) rsmB 525959..527272 (+) 1314 WP_150905432.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  LPB220_RS02800 (LPB220_02800) - 527294..528034 (+) 741 WP_021154558.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  LPB220_RS02805 (LPB220_02805) stkP 528031..529902 (+) 1872 WP_150905434.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  LPB220_RS02810 (LPB220_02810) liaF 530019..530714 (+) 696 WP_049474474.1 cell wall-active antibiotics response protein LiaF -
  LPB220_RS02815 (LPB220_02815) - 530711..531727 (+) 1017 WP_150905436.1 sensor histidine kinase -
  LPB220_RS02820 (LPB220_02820) - 531724..532356 (+) 633 WP_021154562.1 response regulator transcription factor -
  LPB220_RS02825 (LPB220_02825) - 532401..533801 (+) 1401 WP_150905438.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  LPB220_RS02830 (LPB220_02830) - 533803..534168 (+) 366 WP_023920312.1 S1 RNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 68465.61 Da        Isoelectric Point: 6.0303

>NTDB_id=388978 LPB220_RS02805 WP_150905434.1 528031..529902(+) (stkP) [Streptococcus sp. LPB0220]
MIQIGKIFAGRYKIIQQIGRGGMADVYLARDLILDGEEVAVKVLRTNYQTDPIAVARFQREAKAMAELDHPNIVRITDIG
EEEGQQYLAMEYVAGLDLKRYIKENAPLSNEEAVRLMGQILLAMRLAHTRGIIHRDLKPQNVLLTPDGTAKVSDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSIREENKNVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSCLSYERRNEKKLVFEDQAKADTKTLPKVSPTPKTAPVPISEVRSEISSV
DPNRPLSDQQTMAPSKKPRRRLRARYKVLFVAIALVLAAFTFLLYMSPANKTVPDVSGKTIAEARAVIEGQDLQVGEEKE
EYSDSVAEGYVIRTNPNAGAQKKEQSRIDLIVSKGPNSFEMPNYVGETRAKAEEDLKNTYKVSSKMITIEEVETFDYAAG
TVLEQTPAPGEQYSLNSKTKIVLKVAKETTSIEMPNYVGSTYDFARSNLIEIYGIKEANIELRKTEHLPDGVSVSAGQIV
SQTPEVSSTVDINRTRIVLTVYEPKVTASSSTKASSSSDTSSSSSGERSDTESSSSSATGGDS

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=388978 LPB220_RS02805 WP_150905434.1 528031..529902(+) (stkP) [Streptococcus sp. LPB0220]
ATGATTCAAATCGGCAAAATTTTTGCCGGGCGATATAAAATCATCCAACAAATTGGACGCGGCGGGATGGCAGATGTTTA
TCTTGCGCGTGATTTGATTTTAGATGGGGAAGAAGTTGCAGTCAAGGTACTGCGTACGAATTACCAGACGGATCCCATTG
CAGTTGCGCGTTTTCAGCGTGAAGCAAAGGCGATGGCAGAGCTGGACCATCCAAATATCGTTCGGATTACAGATATTGGC
GAAGAAGAAGGACAACAATACCTTGCAATGGAATATGTTGCAGGTTTAGACTTGAAACGCTATATCAAAGAAAATGCTCC
TTTATCAAATGAAGAAGCTGTTCGTTTGATGGGGCAGATCCTTCTAGCTATGCGTCTTGCCCATACGCGTGGCATTATCC
ATAGAGATTTAAAACCACAGAATGTCCTCTTGACACCAGATGGAACAGCAAAAGTTTCAGACTTTGGGATTGCAGTGGCC
TTTGCAGAGACTAGTTTGACCCAGACCAACTCGATGTTGGGGTCGGTTCATTATTTGTCCCCTGAGCAGGCGCGTGGTTC
AAAAGCTACGGTGCAAAGTGACATCTACGCTATGGGAATCATTTTCTATGAGATGTTGACAGGACACATTCCTTATGATG
GAGATAGTGCAGTCACAATTGCTTTGCAGCATTTTCAAAAGCCACTCCCATCTATTCGTGAAGAAAATAAGAATGTTCCA
CAAGCTTTAGAAAATGTAGTGATCAAAGCGACAGCTAAAAAACTGACGGATCGCTATAAATCAGTGGCAGAGATGTATGT
GGATCTTTCAAGTTGCTTGTCCTATGAGAGAAGAAATGAGAAAAAACTGGTTTTTGAAGACCAAGCGAAAGCTGATACAA
AGACTCTTCCAAAAGTGAGTCCAACTCCAAAAACGGCTCCTGTTCCAATCTCTGAAGTACGCAGTGAAATCAGTTCAGTA
GATCCTAATCGACCATTATCTGATCAGCAGACAATGGCGCCAAGTAAAAAGCCAAGAAGACGTTTGCGGGCGCGCTACAA
GGTCTTGTTTGTTGCCATTGCTCTAGTTCTTGCAGCCTTTACTTTCTTGTTGTATATGAGCCCAGCCAATAAAACAGTTC
CAGATGTTTCCGGCAAAACCATTGCCGAAGCTAGAGCGGTTATTGAGGGACAGGACCTTCAAGTCGGTGAAGAGAAAGAA
GAGTACAGTGATTCGGTTGCAGAAGGCTATGTCATTCGAACCAATCCAAATGCAGGGGCCCAAAAGAAAGAACAAAGTCG
AATTGATTTGATTGTTTCAAAAGGACCAAACAGCTTTGAAATGCCAAATTACGTGGGTGAAACACGGGCAAAAGCAGAAG
AAGATTTGAAAAATACTTATAAAGTATCAAGCAAAATGATCACGATTGAAGAAGTTGAGACCTTCGATTATGCTGCAGGG
ACAGTTCTTGAACAAACTCCAGCTCCAGGAGAGCAATATTCTCTGAATTCAAAAACTAAGATTGTTTTGAAAGTAGCGAA
AGAAACAACTTCAATTGAAATGCCAAACTATGTTGGATCAACTTATGATTTTGCTAGAAGTAATTTGATTGAGATCTATG
GTATTAAAGAAGCCAATATCGAATTAAGAAAAACAGAACATCTCCCTGATGGAGTATCTGTTTCTGCAGGTCAAATTGTC
AGTCAAACTCCAGAAGTTTCGAGTACGGTGGATATTAACCGAACACGAATTGTTTTGACTGTATATGAGCCTAAAGTGAC
AGCTTCTTCAAGTACGAAAGCCTCATCAAGTTCTGATACATCTAGTTCATCCTCTGGTGAACGATCAGATACAGAAAGTT
CTAGCAGTAGTGCAACTGGTGGAGATTCATAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-507)

PASTA domain (PASTA)

(512-582)

PASTA domain (PASTA)

(372-434)

Protein kinase domain (Pkinase)

(12-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5J6LL56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

63.22

94.703

0.599
  stkP Streptococcus pneumoniae D39

61.937

96.148

0.596
  stkP Streptococcus pneumoniae R6

61.937

96.148

0.596
  stkP Streptococcus pneumoniae Rx1

62.881

94.703

0.596
  stkP/pknB Streptococcus salivarius strain HSISS4

54.685

94.222

0.515
  pknB Streptococcus mutans UA159

58.932

87.159

0.514

Multiple sequence alignment