Detailed information NTG0387874

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: FOB62_RS05010
• Genome accession: NZ_CP044102
• Coordinates: 995125..996036 (-)
• Length: 303 a.a.
• NCBI ID: WP_003060893.1
• Uniprot ID: A0AAE9U6L1
• Organism: Streptococcus dysgalactiae strain FDAARGOS_654
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 990125..1001036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOB62_RS04990 (FOB62_04990)	-	991140..992915 (-)	1776	WP_003059359.1	acyltransferase family protein	-
FOB62_RS04995 (FOB62_04995)	-	992912..993313 (-)	402	WP_003049089.1	MORN repeat-containing protein	-
FOB62_RS05000 (FOB62_05000)	-	993342..993773 (-)	432	WP_003059365.1	low molecular weight protein-tyrosine-phosphatase	-
FOB62_RS05005 (FOB62_05005)	ruvB	993908..994906 (-)	999	WP_003059357.1	Holliday junction branch migration DNA helicase RuvB	-
FOB62_RS11395	comS	994940..995038 (-)	99	WP_014611913.1	quorum-sensing system DWW-type pheromone	Regulator
FOB62_RS05010 (FOB62_05010)	comR	995125..996036 (-)	912	WP_003060893.1	XRE family transcriptional regulator	Regulator
FOB62_RS05015 (FOB62_05015)	purB	996178..997470 (-)	1293	WP_003056595.1	adenylosuccinate lyase	-
FOB62_RS05020 (FOB62_05020)	-	997519..997728 (-)	210	WP_014611912.1	hypothetical protein	-
FOB62_RS05025 (FOB62_05025)	-	997721..998977 (-)	1257	WP_003055555.1	DUF4041 domain-containing protein	-
FOB62_RS05030 (FOB62_05030)	purK	998987..1000060 (-)	1074	WP_003055561.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
FOB62_RS05035 (FOB62_05035)	purE	1000047..1000535 (-)	489	WP_003055559.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35995.62 Da
• Isoelectric Point: 4.7392

>NTDB_id=387874 FOB62_RS05010 WP_003060893.1 995125..996036(-) (comR) [Streptococcus dysgalactiae strain FDAARGOS_654]
MLEHFGEKVRGLRLEKGISREELCGDEAELSVRQLARIELGQSIPSLAKVIFIAKALEVSVGYLTDGANLELPKRYKELK
YLILRTPTYMDDRKLQVRESQFDEIFENYYDQLPEEEKIAIDIIQAKFEVYQTGDINFGFNILKEFLPQLKKKTVYNLNE
LLLIDLYLIILVVSNFTNDLFDEEFYKEITERILEQHQYLLLEDLFLLNNILLSCADTSIRLKMFERLKDTLQLSHFIMS
TIQDFQRMPMYCMYEWKLSIFYLKDIKRAETYFSQSLTFTQMTNDSYLAQKLQKEWDKDIHPS

Nucleotide

• Length: 912 bp

>NTDB_id=387874 FOB62_RS05010 WP_003060893.1 995125..996036(-) (comR) [Streptococcus dysgalactiae strain FDAARGOS_654]
ATGTTAGAGCATTTTGGTGAAAAAGTGAGAGGATTAAGACTTGAGAAAGGGATTAGTCGAGAGGAATTGTGTGGAGATGA
GGCAGAATTGTCTGTTCGCCAGTTGGCGAGGATAGAGCTAGGTCAATCTATACCAAGTTTAGCGAAGGTTATTTTTATTG
CGAAAGCCTTAGAGGTCAGCGTCGGTTATTTGACGGATGGCGCTAACCTAGAACTCCCTAAACGATATAAAGAGTTAAAA
TATCTCATTTTAAGGACTCCGACTTATATGGACGATCGCAAATTACAGGTCCGGGAGTCTCAGTTTGATGAGATATTTGA
AAACTATTATGATCAATTGCCCGAGGAGGAAAAAATAGCGATTGATATTATCCAGGCAAAATTTGAAGTTTATCAGACAG
GTGATATTAATTTTGGTTTTAATATTTTAAAAGAATTTCTACCACAACTAAAAAAGAAAACGGTTTATAACTTAAATGAA
TTATTATTAATTGATTTATATTTAATTATTTTAGTTGTTTCTAACTTTACAAATGACCTATTTGATGAGGAATTTTATAA
AGAAATAACGGAGCGAATCTTAGAACAGCATCAATACCTGTTATTAGAAGATTTATTTCTATTAAATAATATTCTTTTAT
CTTGCGCAGATACTTCTATTCGTTTAAAAATGTTTGAACGACTAAAGGATACGTTACAACTCAGCCATTTTATTATGTCA
ACCATTCAAGATTTTCAGCGAATGCCCATGTATTGCATGTATGAATGGAAATTGTCTATCTTTTATTTAAAAGATATTAA
ACGAGCAGAAACTTATTTTAGTCAATCTCTCACGTTTACTCAAATGACTAATGATAGTTATTTGGCACAAAAGCTTCAAA
AAGAATGGGATAAGGATATTCATCCCTCTTAA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (12-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	83.389	99.34	0.828
comR	Streptococcus pyogenes MGAS8232	55.629	99.67	0.554
comR	Streptococcus mutans UA159	46.154	98.68	0.455
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.575	96.37	0.449
comR	Streptococcus suis P1/7	37.288	97.36	0.363
comR	Streptococcus suis 05ZYH33	37.288	97.36	0.363